WNT11

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Wingless-type MMTV integration site family, member 11
Identifiers
Symbols WNT11 ; HWNT11
External IDs OMIM603699 MGI101948 HomoloGene20970 GeneCards: WNT11 Gene
RNA expression pattern
PBB GE WNT11 206737 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7481 22411
Ensembl ENSG00000085741 ENSMUSG00000015957
UniProt O96014 P48615
RefSeq (mRNA) NM_004626 NM_009519
RefSeq (protein) NP_004617 NP_033545
Location (UCSC) Chr 11:
75.9 – 75.92 Mb
Chr 7:
98.84 – 98.86 Mb
PubMed search [1] [2]

Protein Wnt-11 is a protein that in humans is encoded by the WNT11 gene.[1][2]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney, and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.[2]

References[edit]

  1. ^ Lako M, Strachan T, Bullen P, Wilson DI, Robson SC, Lindsay S (Dec 1998). "Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung". Gene 219 (1–2): 101–10. doi:10.1016/S0378-1119(98)00393-X. PMID 9757009. 
  2. ^ a b "Entrez Gene: WNT11 wingless-type MMTV integration site family, member 11". 

Further reading[edit]