WNT2

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Wingless-type MMTV integration site family member 2
Identifiers
Symbols WNT2 ; INT1L1; IRP
External IDs OMIM147870 MGI98954 HomoloGene20719 ChEMBL: 1255132 GeneCards: WNT2 Gene
Orthologs
Species Human Mouse
Entrez 7472 22413
Ensembl ENSG00000105989 ENSMUSG00000010797
UniProt P09544 P21552
RefSeq (mRNA) NM_003391 NM_023653
RefSeq (protein) NP_003382 NP_076142
Location (UCSC) Chr 7:
116.92 – 116.96 Mb
Chr 6:
17.99 – 18.03 Mb
PubMed search [1] [2]

Wingless-type MMTV integration site family, member 2, also known as WNT2, is a human gene.[1][2]

This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene.[1]

References[edit]

  1. ^ a b "Entrez Gene: WNT2 wingless-type MMTV integration site family, member 2". 
  2. ^ Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS (June 1988). "Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless". EMBO J. 7 (6): 1743–8. PMC 457162. PMID 2971536. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.