This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis.
Bergstein I, Eisenberg LM, Bhalerao J, et al. (1998). "Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.". Genomics46 (3): 450–8. doi:10.1006/geno.1997.5041. PMID9441749.
Katoh M (2002). "Differential regulation of WNT2 and WNT2B expression in human cancer.". Int. J. Mol. Med.8 (6): 657–60. PMID11712082.
Yarden RI, Brody LC (2002). "Identification of proteins that interact with BRCA1 by Far-Western library screening.". J. Cell. Biochem.83 (4): 521–31. doi:10.1002/jcb.1257. PMID11746496.
Ricken A, Lochhead P, Kontogiannea M, Farookhi R (2002). "Wnt signaling in the ovary: identification and compartmentalized expression of wnt-2, wnt-2b, and frizzled-4 mRNAs.". Endocrinology143 (7): 2741–9. doi:10.1210/en.143.7.2741. PMID12072409.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet.36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
Katoh M (2005). "Molecular evolution of Wnt2b orthologs.". Int. J. Oncol.26 (4): 1135–9. PMID15754012.
Struewing IT, Toborek A, Mao CD (2006). "Mitochondrial and nuclear forms of Wnt13 are generated via alternative promoters, alternative RNA splicing, and alternative translation start sites.". J. Biol. Chem.281 (11): 7282–93. doi:10.1074/jbc.M511182200. PMID16407296.