WNT3A

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Wingless-type MMTV integration site family, member 3A
Identifiers
Symbols WNT3A ; MGC119418; MGC119419; MGC119420
External IDs OMIM606359 MGI98956 HomoloGene22528 ChEMBL: 1255137 GeneCards: WNT3A Gene
RNA expression pattern
PBB GE WNT3A gnf1h01091 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 89780 22416
Ensembl ENSG00000154342 ENSMUSG00000009900
UniProt P56704 P27467
RefSeq (mRNA) NM_033131 NM_009522
RefSeq (protein) NP_149122 NP_033548
Location (UCSC) Chr 1:
228.19 – 228.25 Mb
Chr 11:
59.25 – 59.29 Mb
PubMed search [1] [2]

Protein Wnt-3a is a protein that in humans is encoded by the WNT3A gene.[1][2]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.[2]

References[edit]

  1. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region". Biochem Biophys Res Commun 284 (5): 1168–75. doi:10.1006/bbrc.2001.5105. PMID 11414706. 
  2. ^ a b "Entrez Gene: WNT3A wingless-type MMTV integration site family, member 3A". 

Further reading[edit]