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Wingless-type MMTV integration site family, member 3A
Symbols WNT3A ; MGC119418; MGC119419; MGC119420
External IDs OMIM606359 MGI98956 HomoloGene22528 ChEMBL: 1255137 GeneCards: WNT3A Gene
RNA expression pattern
PBB GE WNT3A gnf1h01091 at tn.png
More reference expression data
Species Human Mouse
Entrez 89780 22416
Ensembl ENSG00000154342 ENSMUSG00000009900
UniProt P56704 P27467
RefSeq (mRNA) NM_033131 NM_009522
RefSeq (protein) NP_149122 NP_033548
Location (UCSC) Chr 1:
228.19 – 228.25 Mb
Chr 11:
59.25 – 59.29 Mb
PubMed search [1] [2]

Protein Wnt-3a is a protein that in humans is encoded by the WNT3A gene.[1][2]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis, adipogenesis etc[3] and in several other developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.[2]


  1. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region". Biochem Biophys Res Commun 284 (5): 1168–75. doi:10.1006/bbrc.2001.5105. PMID 11414706. 
  2. ^ a b "Entrez Gene: WNT3A wingless-type MMTV integration site family, member 3A". 
  3. ^ http://www.jbc.org/content/280/25/24004.full

Further reading[edit]