WNT5B

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Wingless-type MMTV integration site family, member 5B
Identifiers
Symbols WNT5B ; MGC2648
External IDs OMIM606361 MGI98959 HomoloGene22530 GeneCards: WNT5B Gene
RNA expression pattern
PBB GE WNT5B 221029 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 81029 22419
Ensembl ENSG00000111186 ENSMUSG00000030170
UniProt Q9H1J7 P22726
RefSeq (mRNA) NM_030775 NM_001271757
RefSeq (protein) NP_110402 NP_001258686
Location (UCSC) Chr 12:
1.64 – 1.76 Mb
Chr 6:
119.43 – 119.54 Mb
PubMed search [1] [2]

Protein Wnt-5b is a protein that in humans is encoded by the WNT5B gene.[1][2]

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.[2]

References[edit]

  1. ^ Saitoh T, Katoh M (Jul 2001). "Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region". Int J Oncol 19 (2): 347–51. doi:10.3892/ijo.19.2.347. PMID 11445850. 
  2. ^ a b "Entrez Gene: WNT5B wingless-type MMTV integration site family, member 5B". 

Further reading[edit]