From the station's signon in 1940 until 2000, the station was known as WTRY which made an early splash by taking the CBS affiliation from WOKO. The station's original owner was Troy Broadcasting Co. During its 63 years, WTRY, gave birth or adopted three other stations at varying times: WTRI-FM 102.7 (in the early 1950s, went silent), and co-owned WTRI-TV (later became WAST-TV 13 (1959-1981); now, WNYT)from 1954 to 1955 with Van Curler Broadcasting, and WTRY-FM 106.5 (now WPYX) When WROW took the CBS affiliation in 1954, they briefly were the ABC affiliate before WPTR took that affiliation several years later. In the early 1960s, the station took a Top 40 format (which gained a simulcast on 106.5 MHz, now classic rock WPYX, briefly in the early 1970s), which they maintained in some form until the early 1980s when it went through a long-term evolution which resulted in the station becoming oldies in 1986. In 1992, WTRY gained a simulcast on 98.3 FM which they lost in 1994, then regained in a mutual arrangement two years later in which the FM became primary and the AM secondary with the AM splitting for alternate programming at points. WTRY went through several ownership changes: Follow the selling its stake in WTRI, Troy Broadcasting, changes its name to Tri-City Radio, Inc. in late winter of 1956. In 1965, the station was acquired by New Haven based Kops-Monahan Communications. In 1972, WTRY and WTRY-FM (today's WPYX) were sold to Scott Broadcasting of Pennsylvania, Inc. In 1985, television personality Merv Griffin through his company Merv Griffin Enterprises brought the stations and then sold it to Capstar Broadcasting (which was controlled by billionaire mogul Tom Hicks) in 1994. In 1999, Capstar merged with another Hicks-owned company Chancellor Media Corporation to form AM-FM Inc.
After the merger of AM-FM and Clear Channel Communications (now known as iHeartMedia) in 2000, the WTRY stations were permanently split with the AM flipping to sports and becoming WOFX while the oldies format stayed on the FM side.
WTRY was eligible to move from 980 to 1640 kHz however this was never done.
On September 20, 2010, with the flip of WHRL to a simulcast of talk radioWGY, WOFX's programming can now be heard on WGY-FM's HD2 channel.
In addition to Fox Sports network programming, the station is home to Jay Mohr Sports in middays. Previously, WOFX aired Imus in the Morning, a program which predated the sports format, however the show was taken off the schedule at the end of 2006 and replaced by Fox Sports Radio's Steve Czaban.
In the rare case of play by play conflicts, the latter games are usually heard on sister WTRY-FM, a procedure that has become more solidly done in the wake of the mild success of UAlbany football and the success of the Mets in the 2006 season.