Like many college radio stations, 99.5 WUSR Scranton Royal Radio carries a diverse range of programming. During the week from 8-10 a.m., the Pell Radio Reading Service, which is being offered in partnership with the Department of Communication and the Lackawanna Branch of the Pennsylvania Association for the Blind, orates daily news updates from the local Times-Tribune newspaper in Scranton, Pa.
The station primarily broadcasts several hours of Alternative, Loud Rock, Urban, Sports Talk and General Talk shows. All shows for each genre last two hours. Weekends primarily consist of freeform programming, with many specialty shows focusing on musical genres and topics such as soundtracks, Blues, and Polka.