Arriving in Quebec City in July 1862, they travelled across the continent, wintering near Fort Carlton. After a challenging and at times humorous summer they reached Victoria, BC.
On returning home, with Milton, he co-authored a book on their adventures, The North-West Passage by Land (London, 1865), which described their expedition in considerable detail, which gained a lot of attention.
He continued his medical studies and received his doctorate in 1865, became assistant at the St Mary's Hospital (London) in 1866 and from 1869 he was, for 23 years, at the Hospital for Sick Children, Great Ormond Street, where he was dean of the medical faculty from 1869 to 1873. At the time of his death he was consulting physician at the St. Mary's Hospital. He was an ardent advocate of women in the study of medicine.