Weber–Christian disease (also known as "Idiopathic Relapsing febrile non-suppurative panniculitis") is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin.
It is type of panniculitis. It is a rare disease seen in females 30-60years of age.Its is a recurring inflammation of fatty layers of tissue present beneath the skin.Clinical course is characterised by exacerbations and remissions.Lesions are bilaterally symmetrical & are usually seen in lower legs.
^F. P. Weber. A case of relapsing non-suppurative nodular panniculitis, showing phagocytosis of subcutaneous fat-cells by macrophages. British Journal of Dermatology and Syphilis, Oxford, 1925, 37: 301-311.
^H. A. Christian. Relapsing febrile nodular nonsuppurative panniculitis. Archives of Internal Medicine, Chicago, 1928, 42: 338-351.