"Welcome to Wherever You Are" failed to gain success in the US, but it reached the top 40 in several European countries, including the UK (#19),Italy (#33) and Germany (#40). Speaking about the song on Larry King Live, Jon Bon Jovi said "I thought for sure this was going to be a universal, timeless theme song of unity, diversity. Not a hit, not even close. Swing and a miss".
"Welcome to Wherever You Are" is a song of affirmation, about accepting who you are and being comfortable in your own skin. Jon Bon Jovi claims the song is greatly influenced by events during the 2004 Presidential Election. Jon campaigned for John Kerry during that time. The song is also notable for being one of the few Bon Jovi songs lacking a guitar solo.
The song also shares its name with an episode of The West Wing's seventh season, in which Jon Bon Jovi appears endorsing the fictional presidential nomination Matt Santos.