The Wenro were discovered by Franciscan missionary Joseph de La Roche Daillon in 1627 at the site of Oil Springs. Dallion noted the tribe's use of crude petroleum (then a largely unknown substance) as an alleged medicine, a possible factor in the tribe's eventual demise. Along with the Neutral and Erie Nations, they were ultimately destroyed by the Iroquois nations during the Beaver Wars, and were assimilated into the victorious nations. Many were absorbed into the Seneca, who inhabit the territory today. Remaining survivors were exiled into Huron territory.