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West Virginia Route 106 is an unsigned state route for the cable-stayed East Huntington Bridge crossing the Ohio River from the Guyandotte section of Huntington to Proctorville, Ohio. While unsigned from the ground, it is shown on maps as a labeled state route.
The northern approach (from Ohio State Route 7) is the recently-extended Ohio State Route 775; its southern terminus is a pair of ramps (northbound on-ramp from Fifth Avenue, southbound offramp to Third Avenue) connecting it to U.S. Route 60.
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