The arena is home to the University of New Hampshire Wildcats men's and women's ice hockey teams. The hockey rink has a full Olympic-sized sheet of ice. In 2002 and 2005, UNH and the Whittemore Center hosted the NCAA Womens Frozen Four. The arena can seat 6,501 for hockey and basketball games, and 7,200 for concerts and similar events. The lobby is decorated with heroic portraits of past men's and women's All American hockey players. Through the end of the 2006-2007 academic year, the arena was managed by Global Spectrum, but UNH Campus Recreation took over management before the 2007 academic year.
The basketball teams (which currently draw roughly 1,000 fans per game on average) normally play across the street at Lundholm Gymnasium, which is attached to Cowell Stadium. A few home basketball games have been held at the Whittemore Center. The arena is also a venue for many concerts, trade shows, and events. This was New Hampshire's largest arena until the Verizon Wireless Arena was built in Manchester.