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Original route of the Circle Line (grey) following Nicoll Highway (pink), and the realigned route (orange)
Original route of the Circle Line (grey) following Nicoll Highway (pink), and the realigned route (orange)

The Nicoll Highway collapse occurred in Singapore on 20 April 2004 when a Mass Rapid Transit tunnel construction site caved in near the highway next to the Merdeka Bridge. Four workers were killed and three were injured, delaying the construction of the Circle Line. The collapse was caused by a poorly designed strut-waler support system, a lack of monitoring and proper management of data caused by human error, and organisational failures of the construction contractors and the Land Transport Authority. Following the incident, the collapsed site was refilled, and the highway was reinstated and reopened to traffic on 4 December 2004. The authorities revised their construction safety measures to be above industry standards. The Circle Line tunnels were realigned (map pictured), with Nicoll Highway station rebuilt underneath Republic Avenue, to the south of the original site. The station and tunnels opened on 17 April 2010, three years later than planned. (Full article...)

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In chemistry, an amino acid is a molecule containing both amine and carboxyl functional groups. In biochemistry, this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where R is an organic substituent.[1] In the alpha amino acids, the amino and carboxylate groups are attached to the same carbon, which is called the α–carbon. The various alpha amino acids differ in which side chain (R group) is attached to their alpha carbon. They can vary in size from just a hydrogen atom in glycine through a methyl group in alanine to a large heterocyclic group in tryptophan.

Beyond the amino acids that are found in all forms of life, many non-natural amino acids have vital roles in technology and industry. For example, the chelating agents EDTA and nitrilotriacetic acid are alpha amino acids that are important in the chemical industry. (more...)

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Tarazona

Tarazona is a town and municipality, and the capital of the comarca Tarazona y el Moncayo in Aragon, Spain. It is also the seat of the Roman Catholic Diocese of Tarazona. Located on the river Queiles, a tributary of the Ebro, Tarazona was an important regional centre of ancient Rome, known as Turiaso, located around 60 kilometres (37 miles) from Bilbilis. The city later came under the rule of the Visigoths, who called it Tirasona. This view of Tarazona was taken from the city's episcopal palace, and shows Tarazona Cathedral and its seminary, the Old Bullfight Arena, and the Sanctuary of the Lady of the River.

Photograph credit: Diego Delso

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  1. ^ Proline is an exception to this general formula. It lacks the NH2 group because of the cyclization of the side chain.