The Conservative loss in this seat, which came close to the last possible date for a general election, meant that they no longer had a majority in the House of Commons. Wirral South was the last in a run of significant Conservative losses, following a period of dissatisfaction with the Major years. This was the last Conservative loss to Labour in a by-election until the Corby by-election, 2012.
As with almost all constituencies fought at the 1997 May election, Wirral South was subject to boundary changes. Labour has held the seat since the by-election.