The municipality as it is now originated in 1977, when Wuustwezel merged with the municipality of Loenhout. It now consists of three major villages, Wuustwezel proper, Gooreind and Loenhout, and two minor hamlets, Braken and Sterbos.
On January 1, 2006 Wuustwezel had a total population of 18,338; in 2005 there were 8,238 residents in Wuustwezel, 6,340 in Gooreind and 3,603 in Loenhout. There were also 1,039 residents with a non-Belgian nationality. The total area is 89.43 km² which gives it a population density of 205 inhabitants per km².