From Wikipedia, the free encyclopedia
Jump to: navigation, search
Exportin 6
Symbols XPO6 ; EXP6; RANBP20
External IDs OMIM608411 MGI2429950 HomoloGene12544 GeneCards: XPO6 Gene
RNA expression pattern
PBB GE XPO6 211982 x at tn.png
PBB GE XPO6 214784 x at tn.png
PBB GE XPO6 gnf1h05757 s at tn.png
More reference expression data
Species Human Mouse
Entrez 23214 74204
Ensembl ENSG00000169180 ENSMUSG00000000131
UniProt Q96QU8 Q924Z6
RefSeq (mRNA) NM_001270940 NM_028816
RefSeq (protein) NP_001257869 NP_083092
Location (UCSC) Chr 16:
28.11 – 28.22 Mb
Chr 7:
126.1 – 126.2 Mb
PubMed search [1] [2]

Exportin-6 is a protein that in humans is encoded by the XPO6 gene.[1][2]

Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of RAN (MIM 601179)-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.[supplied by OMIM][2]


Further reading[edit]