Y-27632

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Y-27632
Y-27632.svg
Identifiers
CAS number 146986-50-7 YesY
PubChem 448042
ChemSpider 20016532 YesY
DrugBank DB08756
ChEBI CHEBI:75393 N
ChEMBL CHEMBL2218937 N
Jmol-3D images Image 1
Properties
Molecular formula C14H21N3O
Molar mass 247.34 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Y-27632 is a biochemical tool used in the study of the rho-associated protein kinase (ROCK) signaling pathways.[1] Y-27632 selectively inhibits p160ROCK.[2]

References[edit]

  1. ^ Uehata, Masayoshi (1999). "Y-27632. Selective probe of ROCK/Rho-kinase". Jikken Igaku 17 (7): 850–855. 
  2. ^ Uehata, M; Ishizaki, T; Satoh, H; Ono, T; Kawahara, T; Morishita, T; Tamakawa, H; Yamagami, K et al. (1997). "Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension". Nature 389 (6654): 990–4. doi:10.1038/40187. PMID 9353125.