Y linkage

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In mammals, Y-linkage, also known as holandric inheritance, is the determination of a phenotypic trait by an allele (or gene) on the Y chromosome.


Because the Y-chromosome is small and does not contain many genes, few traits are Y-linked, and Y-linked diseases are rare. Since the only humans who have a Y chromosome are males, Y-linked traits are passed only from father to son, with no interchromosomal genetic recombination.

Y-Chromosome deletions are a frequent genetic cause of male infertility. Having hairy ears was once thought to be a Y-linked trait in humans,[1] but that hypothesis has been discredited.[2]

Genes known to be contained on the Y chromosome[edit]

As of the year 2000, a number of genes were known to be Y-linked, including:[3]

See also[edit]


  1. ^ Online Mendelian Inheritance of Man, HAIRY EARS, Y-LINKED, although see HAIRY EARS.
  2. ^ "Genetics of hairy ears in south Indians. [Clin Exp Dermatol. 1990] - PubMed - NCBI". Ncbi.nlm.nih.gov. 2014-05-14. Retrieved 2014-06-29. 
  3. ^ "Y-linked gene definition - Medical Dictionary: Definitions of Popular Terms Defined on MedTerms". Medterms.com. 2012-09-20. Retrieved 2014-06-29. 

External links[edit]