|This article needs additional citations for verification. (April 2009)|
Because the Y-chromosome is small and does not contain many genes, few traits are Y-linked, and Y-linked diseases are rare. Since the only humans who have a Y chromosome are males, Y-linked traits are passed only from father to son, with no interchromosomal genetic recombination.
Genes known to be contained on the Y chromosome
As of the year 2000, a number of genes were known to be Y-linked, including:
- ASMTY (acetylserotonin methyltransferase),
- TSPY (testis-specific protein),
- IL3RAY (interleukin-3 receptor),
- SRY (sex-determining region),
- TDF (testis determining factor),
- ZFY (zinc finger protein),
- PRKY (protein kinase, Y-linked),
- AMGL (amelogenin),
- CSF2RY (granulocyte-macrophage, colony-stimulating factor receptor, alpha subunit on the Y chromosome),
- ANT3Y (adenine nucleotide translocator-3 on the Y),
- SOX21 (known to cause baldness),
- AZF2 (azoospermia factor 2),
- BPY2 (basic protein on the Y chromosome),
- AZF1 (azoospermia factor 1),
- DAZ (Spermatogenes is deleted in azoospermia),
- RBM1 (RNA binding motif protein, Y chromosome, family 1, member A1),
- RBM2 (RNA binding motif protein 2), and
- UTY (ubiquitously transcribed TPR gene on Y chromosome).
- Online Mendelian Inheritance of Man, HAIRY EARS, Y-LINKED, although see HAIRY EARS.
- "Genetics of hairy ears in south Indians. [Clin Exp Dermatol. 1990] - PubMed - NCBI". Ncbi.nlm.nih.gov. 2014-05-14. Retrieved 2014-06-29.
- "Y-linked gene definition - Medical Dictionary: Definitions of Popular Terms Defined on MedTerms". Medterms.com. 2012-09-20. Retrieved 2014-06-29.
|This genetics article is a stub. You can help Wikipedia by expanding it.|