Yang Zhi originally started his professional career at the second tier club Guangdong Xiongying after graduating from their youth team. He quickly established himself within the squad in his first professional season with Guangdong Xiongying by playing in 26 league games. The following season he would play in a further 22 league games for Guangdong and help take them to tenth place in the league. His performances caught the eye of Beijing Guoan and with the chance to play in the Chinese Super League, Yang Zhi transferred to them at the beginning of the 2005 league season where he once again quickly established himself as their first choice goalkeeper within the team by playing in 21 league games in his debut season. The following seasons saw him become an integral member of the team and by the 2009 league season he had aided them to win the Chinese Super League title. During the preseason of the 2012 season, Yang Zhi sustained an injury in a friendly and was out for most of the season. He returned to his starting role as goalkeeper for Beijing during the 2013 season.
After his consistent performances for Beijing Guoan, he was called up to the Chinese national team on August 10, 2006 in a friendly against Thailand where he came on as a substitute for Li Leilei in a 4–0 victory. He would later make his competitive debut the following season against Myanmar on October 28, 2007 for a 2010 FIFA World Cup qualification game, which China won 4–0. It was not until the introduction of new head coach Gao Hongbo that saw Yang Zhi promoted to become the national team's first choice goalkeeper when he named him within his first game in a friendly against Germany on May 29, 2009 that ended in a 1–1 draw.