"You're Makin' Me High" became Braxton's first number-one single on both the Billboard Hot 100 and Hot R&B/Hip-Hop Songs charts; it remained on top for one week on the former and for two weeks on the latter, eventually going platinum as rated by the RIAA. A danceremix by Morales allowed the single to also top the Hot Dance Club Play chart for two weeks in August 1996. Another remix for urban markets was created featuring rapper Foxy Brown, called the "Groove Mix".
The music video, directed by Bille Woodruff, features Braxton and a group of friends (consisting of actresses Erika Alexander, Vivica A. Fox, and Tisha Campbell-Martin) enjoying themselves in luxurious surroundings. An elevator brings up a series of men, some very attractive and others amusingly unattractive. Braxton and her friends "judge" the men using oversized playing cards as score cards. Periodically, one of the women chooses a man to leave with. Braxton chooses Bryce Wilson, and they are shown together in a bathtub of cotton candy and on a dance floor.