Yt antigen system
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The Yt antigen system (also known as Cartwright) is present on the membrane of red blood cells and helps determine a person's blood type. The antigens are found on the protein acetylcholinesterase, an enzyme which helps break down acetylcholine.[1] The Yt system features two alleles, Yt(a) and Yt(b). Antibodies against the Yt system can lead to transfusion reactions such as hemolytic anemia.
[edit] References
Online 'Mendelian Inheritance in Man' (OMIM) 112100 - OMIM page on Yt antigen
- ^ Bartels, CF; Zelinski, T; Lockridge, O (1993). "Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism". American journal of human genetics 52 (5): 928–36. PMC 1682033. PMID 8488842. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1682033.
[edit] External links
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