Yunnan Baiyao

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Yunnan Baiyao (or Yunnan Paiyao) (simplified Chinese: 云南白药; traditional Chinese: 雲南白藥) is a hemostatic powdered medicine famous for being carried by the Vietcong to stop bleeding during the Vietnam War. [1] The medicine, developed by Qu Huangzhang in 1902, is designated as one of two Class-1 protected traditional medicines, which gives it 20 years protection. In China, its reputation is equal to that of penicillin in the U.S.[2] It is founded and manufactured by a state-owned enterprise, Yunnan Baiyao Group (SZSE: 000538) in Yunnan, China.

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[edit] Origination

The inventor was a Chinese man named Qu Huanzhang from Jiangchuan County in Yunnan Province[citation needed], and had set out to explore the entire region and taste its hundreds of herbs. In 1902 he formulated "Qu Huanzhang Panacea" which became Yunnan Baiyao ("White medicine from Yunnan")[3]In the massive Taierzhuang Battle of 1938 (between Chinese and Japanese forces), Mr. Qu Huanzhang donated more than 30,000 bottles of Yunnan Baiyao to the army, thereby saving the lives of many soldiers.

As an indication of its value, it is noted that during the 1940s, army commander Wu Xuexian was seriously injured in his right leg. The French hospital in Kunming (capital of Yunnan) recommended amputation to save Wu's life. Mr. Wu turned to Mr. Qu for help, and to everyone's surprise, recovered without the need for an amputation. Yunnan Baiyao gained the reputation as a miracle remedy. After the death of Mr. Qu, his wife, Liao Lanying, donated the secret prescription to the government.[3]

[edit] Treatment

The main ingredients are both steamed and raw Sanqi, (roots of Tienchi ginseng, also known as "Notoginseng," Panax pseudoginseng) used to normalize blood flow, enhance poor circulation and heal internal bleeding in injuries and bleeding ulcers, and Rhizoma Dioscoreae [4]. These two ingredients are then combined with astringent herbs that absorb excess bleeding, invigorate the blood and enhance healing including myrrh and dragon's blood a resinous for internal bleeding.[5]

[edit] Formula

Its exact formula is a closely guarded secret. The company website mentions that progesterone has been analyzed from the formula, several saponins, alkaloids and the pharmacologically active compound calcium phosphate. [2] However the progesterone may not exist in that state provided that the formula is still the traditional formula since Dioscorea requires laboratory alteration to become progesterone. [6]The separate herbal ingredients are reportedly made up by thirteen separate teams, none of whom have any knowledge of the ingredients the other teams are mixing. The individual mixed components are then combined by a further team, who have no knowledge of what constitutes them but knows the proportions in which they are combined.

[edit] Secret ingredients leaked by FDA

In December 2010 a list of ingredients were found published on the websites of Amazon.com and the Food and Drug Administration (FDA), the American regulatory body for pharmaceuticals.[7]. The list supposedly containing eight active ingredients of a liquid form of the drug were found in a document published on the FDA website[8] that contains correspondence between the FDA and a distributor of the drug. Ingredient lists are also present in the product information sections for the powdered and capsule forms of the drug on Amazon.com.[9] Although the proportions and exact manufacturing processes are still unknown for Yunnan Baiyao, this development opens the door for copycat products based on the formulation.

[edit] Clinical trials

Yunnan Baiyao has been found to reduce post-operative bleeding [10]. It is also been shown to be an effective medicine in inflammatory bowel disease [11].

[edit] References

  1. ^ Materia Medica
  2. ^ a b CBW-Yunnan Baiyao, one of the most famous Chinese Companies in all Chinese Provinces of China, Yunnan Province
  3. ^ a b Jintu - Yunnan Baiyao Plaster
  4. ^ YUNNAN BAIYAO natural pain relief from China - Rivet Trading cc South Africa
  5. ^ http://www.asianhealthsecrets.com/letha/?p=90 Letha Hadady Asian Health Secrets
  6. ^ http://www.henriettesherbal.com/faqs/medi-2-12-wild-yam.html Wild Yam FAQ
  7. ^ http://www.gochengdoo.com/en/blog/item/1982/yunnan_baiyao_secret_ingredients_found_on_us_websites Yunnan Baiyao secret ingredients found on US websites
  8. ^ http://www.fda.gov/ohrms/DOCKETS/dailys/02/Sep02/091102/97s-0163-let0634-vol18.pdf FDA document containing ingredients
  9. ^ http://www.amazon.com/Yunnan-Baiyao-Capsule-Jiao-Capsules/dp/B002S9KPPG/ref=sr_1_1?ie=UTF8&qid=1292818235&sr=8-1 Product information of Yunnan Baiyao
  10. ^ Tang, Z-L; Wang, X; Yi, B; Li, Z-L; Liang, C; Wang, X-X (2009). "Effects of the preoperative administration of Yunnan Baiyao capsules on intraoperative blood loss in bimaxillary orthognathic surgery: a prospective, randomized, double-blind, placebo-controlled study.". International journal of oral and maxillofacial surgery 38 (3): 261–6. PMID 19153029. 
  11. ^ Li, Richard; Alex, Philip; Ye, Mei; Zhang, Ting; Liu, Ling; Li, Xuhang (2011). "An old herbal medicine with a potentially new therapeutic application in inflammatory bowel disease.". International journal of clinical and experimental medicine 4 (4): 309–19. PMID 22140602. 

[edit] External links

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