ZNF638

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Zinc finger protein 638
Identifiers
Symbols ZNF638 ; NP220; ZFML; Zfp638
External IDs OMIM614349 MGI1203484 HomoloGene7447 GeneCards: ZNF638 Gene
RNA expression pattern
PBB GE ZNF638 213775 x at tn.png
PBB GE ZNF638 211257 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 27332 18139
Ensembl ENSG00000075292 ENSMUSG00000030016
UniProt Q14966 Q61464
RefSeq (mRNA) NM_001014972 NM_001166371
RefSeq (protein) NP_001014972 NP_001159843
Location (UCSC) Chr 2:
71.5 – 71.66 Mb
Chr 6:
83.91 – 83.99 Mb
PubMed search [1] [2]

Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.[1][2]

The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.[2]

Interactions[edit]

ZNF638 has been shown to interact with FHL2.[3]

References[edit]

  1. ^ Inagaki H, Matsushima Y, Nakamura K, Ohshima M, Kadowaki T, Kitagawa Y (Jul 1996). "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain". J Biol Chem 271 (21): 12525–31. doi:10.1074/jbc.271.21.12525. PMID 8647861. 
  2. ^ a b "Entrez Gene: ZNF638 zinc finger protein 638". 
  3. ^ Ng, Enders Kai On; Chan Kwok Keung; Wong Chi Hang; Tsui Stephen Kwok Wing; Ngai Sai Ming; Lee Simon Ming Yuen; Kotaka Masayo; Lee Cheuk Yu; Waye Mary Miu Yee; Fung Kwok Pui (2002). "Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220". J. Cell. Biochem. (United States) 84 (3): 556–66. doi:10.1002/jcb.10041. ISSN 0730-2312. PMID 11813260. 

Further reading[edit]

External links[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.