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Zinc finger, RAN-binding domain containing 2
Protein ZRANB2 PDB 1n0z.png
PDB rendering based on 1n0z.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols ZRANB2 ; ZIS; ZIS1; ZIS2; ZNF265
External IDs OMIM604347 MGI1858211 HomoloGene135921 GeneCards: ZRANB2 Gene
Species Human Mouse
Entrez 9406 53861
Ensembl ENSG00000132485 ENSMUSG00000028180
UniProt O95218 Q9R020
RefSeq (mRNA) NM_005455 NM_017381
RefSeq (protein) NP_005446 NP_059077
Location (UCSC) Chr 1:
71.06 – 71.08 Mb
Chr 3:
157.53 – 157.55 Mb
PubMed search [1] [2]

Zinc finger Ran-binding domain-containing protein 2 is a protein that in humans is encoded by the ZRANB2 gene.[1][2] The sequence is TRALLPHEKD LIQVRHLLLR GTEREVVLDL LHLVIAKKDE QDHGHPKDAT GHHLDHPILV PVQVQKRNNV LKFTS.[3]


ZRANB2 has been shown to interact with U2 small nuclear RNA auxiliary factor 1[4] and SNRP70.[4]


  1. ^ Nakano M, Yoshiura K, Oikawa M, Miyoshi O, Yamada K, Kondo S, Miwa N, Soeda E, Jinno Y, Fujii T, Niikawa N (February 1999). "Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene". Gene 225 (1–2): 59–65. doi:10.1016/S0378-1119(98)00536-8. PMID 9931435. 
  2. ^ "Entrez Gene: ZRANB2 zinc finger, RAN-binding domain containing 2". 
  3. ^ http://www.uniprot.org/uniprot/Q68DP0
  4. ^ a b Adams, D J; van der Weyden L; Mayeda A; Stamm S; Morris B J; Rasko J E (July 2001). "ZNF265--a novel spliceosomal protein able to induce alternative splicing". J. Cell Biol. (United States) 154 (1): 25–32. doi:10.1083/jcb.200010059. ISSN 0021-9525. PMC 2196870. PMID 11448987. 

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