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Zometapine structure.svg
Systematic (IUPAC) name
Clinical data
Legal status
CAS number 51022-73-2 YesY
ATC code ?
PubChem CID 5361110
ChemSpider 4514671 N
UNII 9171J97IQP YesY
Chemical data
Formula C14H15ClN4 
Molecular mass 274.749
 N (what is this?)  (verify)

Zometapine (CI-781) is an antidepressant drug which is a pyrazolodiazepine derivative. Its molecular structure closely resembles benzodiazepines and is unrelated to other antidepressant drug classes.[1]

Zometapine Rxn.png

DeWald, H. A.; Lobbenstael, S. J.; 1974, U.S. Patent 3,823,157.

As can be seen, the product is capable of tautomerizing.

See also[edit]


  1. ^ Katz, RJ. (Oct 1984). "Effects of zometapine, a structurally novel antidepressant, in an animal model of depression.". Pharmacol Biochem Behav 21 (4): 487–90. doi:10.1016/s0091-3057(84)80027-1. PMID 6542226.