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{
"parse": {
"title": "Rosetta@home",
"pageid": 3255539,
"revid": 255139603,
"text": {
"*": "<div class=\"mw-content-ltr mw-parser-output\" lang=\"en\" dir=\"ltr\"><style data-mw-deduplicate=\"TemplateStyles:r1218072481\">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data div{background:#1f1f23!important;color:#f8f9fa}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data div{background:#1f1f23!important;color:#f8f9fa}}</style><table class=\"infobox vevent\"><caption class=\"infobox-title summary\">Rosetta@home</caption><tbody><tr><td colspan=\"2\" class=\"infobox-image logo\"><span class=\"mw-default-size\" typeof=\"mw:Error mw:File\"><a href=\"//en.wikipedia.org/wiki/Special:Upload?wpDestFile=Rosetta_at_home_logo.png\" class=\"new\" title=\"File:Rosetta at home logo.png\"><span class=\"mw-file-element mw-broken-media\">File:Rosetta at home logo.png</span></a></span></td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\"><a href=\"/wiki/Programmer\" title=\"Programmer\">Developer(s)</a></th><td class=\"infobox-data\">Baker laboratory, University of Washington; Rosetta Commons</td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\">Initial release</th><td class=\"infobox-data\">October 6, 2005<span style=\"display:none\"> (<span class=\"bday dtstart published updated itvstart\">2005-10-06</span>)</span></td></tr><tr style=\"display: none;\"><td colspan=\"2\" class=\"infobox-full-data\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1218072481\"></td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\"><a href=\"/wiki/Software_release_life_cycle\" title=\"Software release life cycle\">Stable release</a></th><td class=\"infobox-data\"><div style=\"margin:0px;\">Rosetta Beta: 5.98, Rosetta Mini: 1.40\n </div></td></tr><tr style=\"display:none\"><td colspan=\"2\">\n</td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\"><a href=\"/wiki/Operating_system\" title=\"Operating system\">Operating system</a></th><td class=\"infobox-data\"><a href=\"/wiki/Cross-platform\" class=\"mw-redirect\" title=\"Cross-platform\">Cross-platform</a></td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\"><a href=\"/wiki/Computing_platform\" title=\"Computing platform\">Platform</a></th><td class=\"infobox-data\"><a href=\"/wiki/BOINC\" class=\"mw-redirect\" title=\"BOINC\">BOINC</a></td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\"><a href=\"/wiki/Software_license\" title=\"Software license\">License</a></th><td class=\"infobox-data\">Free for academic and non-profit use, proprietary license available for commercial use<sup id=\"cite_ref-1\" class=\"reference\"><a href=\"#cite_note-1\">[1]</a></sup></td></tr><tr><th scope=\"row\" class=\"infobox-label\" style=\"white-space: nowrap;\">Website</th><td class=\"infobox-data\"><a rel=\"nofollow\" class=\"external free\" href=\"http://boinc.bakerlab.org/rosetta\">http://boinc.bakerlab.org/rosetta</a></td></tr></tbody></table>\n<p><b>Rosetta@home</b> is a <a href=\"/wiki/Distributed_computing\" title=\"Distributed computing\">distributed computing</a> project for <a href=\"/wiki/Protein_structure_prediction\" title=\"Protein structure prediction\">protein structure prediction</a> on the <a href=\"/wiki/Berkeley_Open_Infrastructure_for_Network_Computing\" title=\"Berkeley Open Infrastructure for Network Computing\">Berkeley Open Infrastructure for Network Computing</a> (BOINC) platform, run by the <a href=\"/wiki/David_Baker_(biochemist)\" title=\"David Baker (biochemist)\">Baker laboratory</a> at the <a href=\"/wiki/University_of_Washington\" title=\"University of Washington\">University of Washington</a>. Rosetta@home also aims to predict <a href=\"/wiki/Protein-protein_docking\" class=\"mw-redirect\" title=\"Protein-protein docking\">protein-protein docking</a> and <a href=\"/wiki/Protein_design\" title=\"Protein design\">design new proteins</a> with the help of over 86,000 volunteered computers processing over 77 <a href=\"/wiki/TeraFLOPS\" class=\"mw-redirect\" title=\"TeraFLOPS\">teraFLOPS</a> on average as of November 30, 2008.<sup id=\"cite_ref-BOINCstats_RosettaOverview_2-0\" class=\"reference\"><a href=\"#cite_note-BOINCstats_RosettaOverview-2\">[2]</a></sup> Though much of the project is oriented towards <a href=\"/wiki/Research#Basic_research\" title=\"Research\">basic research</a> on improving the accuracy and robustness of the <a href=\"/wiki/Proteomics\" title=\"Proteomics\">proteomics</a> methods, Rosetta@home also does applied research on <a href=\"/wiki/Malaria\" title=\"Malaria\">malaria</a>, <a href=\"/wiki/Alzheimer%27s_disease\" title=\"Alzheimer's disease\">Alzheimer's disease</a> and other pathologies.<sup id=\"cite_ref-3\" class=\"reference\"><a href=\"#cite_note-3\">[3]</a></sup>\n</p><p>Like all BOINC projects, Rosetta@home uses idle computer processing resources from volunteers' computers to perform calculations on individual <a href=\"/wiki/BOINC_client-server_technology\" class=\"mw-redirect\" title=\"BOINC client-server technology\">workunits</a>. Completed results are sent to a central project <a href=\"/wiki/Server\" class=\"mw-disambig\" title=\"Server\">server</a> where they are validated and assimilated into project <a href=\"/wiki/Database\" title=\"Database\">databases</a>. The project is <a href=\"/wiki/Cross-platform\" class=\"mw-redirect\" title=\"Cross-platform\">cross-platform</a>, and runs on a wide variety of <a href=\"/wiki/Hardware\" class=\"mw-disambig\" title=\"Hardware\">hardware</a> configurations. Users can view the progress of their individual protein structure prediction on the Rosetta@home <a href=\"/wiki/Screensaver\" title=\"Screensaver\">screensaver</a>.\n</p><p>In addition to disease-related research, the Rosetta@home network serves as a testing framework for new methods in <a href=\"/wiki/Structural_bioinformatics\" title=\"Structural bioinformatics\">structural bioinformatics</a>. These new methods are then used in other Rosetta-based applications, like <a class=\"mw-selflink-fragment\" href=\"#RosettaDock\">RosettaDock</a> and the <a href=\"/wiki/Human_Proteome_Folding_Project\" title=\"Human Proteome Folding Project\">Human Proteome Folding Project</a>, after being sufficiently developed and proven stable on Rosetta@home's large and diverse collection of volunteer computers. Two particularly important tests for the new methods developed in Rosetta@home are the <a href=\"/wiki/Critical_Assessment_of_Techniques_for_Protein_Structure_Prediction\" class=\"mw-redirect\" title=\"Critical Assessment of Techniques for Protein Structure Prediction\">Critical Assessment of Techniques for Protein Structure Prediction</a> (CASP) and <a href=\"/wiki/Critical_Assessment_of_Prediction_of_Interactions\" title=\"Critical Assessment of Prediction of Interactions\">Critical Assessment of Prediction of Interactions</a> (CAPRI) experiments, biannual experiments which evaluate the <a href=\"/wiki/State_of_the_art\" title=\"State of the art\">state of the art</a> in protein structure prediction and protein-protein docking prediction, respectively. Rosetta@home consistently ranks among the foremost docking predictors, and is one of the best <a href=\"/wiki/Tertiary_structure\" class=\"mw-redirect\" title=\"Tertiary structure\">tertiary structure</a> predictors available.<sup id=\"cite_ref-CAPRI3_4-0\" class=\"reference\"><a href=\"#cite_note-CAPRI3-4\">[4]</a></sup>\n</p>\n<meta property=\"mw:PageProp/toc\" />\n<h2><span class=\"mw-headline\" id=\"Computing_platform\">Computing platform</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=1\" title=\"Edit section: Computing platform\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<style data-mw-deduplicate=\"TemplateStyles:r1033289096\">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}</style><div role=\"note\" class=\"hatnote navigation-not-searchable\">See also: <a href=\"/wiki/List_of_distributed_computing_projects\" class=\"mw-redirect\" title=\"List of distributed computing projects\">List of distributed computing projects</a></div>\n<p>Both the Rosetta@home application and the <a href=\"/wiki/BOINC\" class=\"mw-redirect\" title=\"BOINC\">BOINC</a> distributed computing platform are available for the <a href=\"/wiki/Microsoft_Windows\" title=\"Microsoft Windows\">Microsoft Windows</a>, <a href=\"/wiki/Linux\" title=\"Linux\">Linux</a> and <a href=\"/wiki/Macintosh\" class=\"mw-redirect\" title=\"Macintosh\">Macintosh</a> platforms (BOINC also runs on several other platforms, e.g. FreeBSD).<sup id=\"cite_ref-BOINCClient_5-0\" class=\"reference\"><a href=\"#cite_note-BOINCClient-5\">[5]</a></sup> Participation in Rosetta@home requires a <a href=\"/wiki/Central_processing_unit\" title=\"Central processing unit\">central processing unit</a> (CPU) with a <a href=\"/wiki/Clock_speed\" class=\"mw-redirect\" title=\"Clock speed\">clock speed</a> of at least 500 <a href=\"/wiki/Hertz\" title=\"Hertz\">MHz</a>, 200 <a href=\"/wiki/Megabyte\" title=\"Megabyte\">megabytes</a> of free <a href=\"/wiki/Hard_disk_drive\" title=\"Hard disk drive\">disk space</a>, 256 megabytes of <a href=\"/wiki/Physical_memory\" class=\"mw-redirect\" title=\"Physical memory\">physical memory</a>, and Internet connectivity.<sup id=\"cite_ref-6\" class=\"reference\"><a href=\"#cite_note-6\">[6]</a></sup> As of September 7, 2008, the current version of the Rosetta application is 5.96,<sup id=\"cite_ref-oldNews_7-0\" class=\"reference\"><a href=\"#cite_note-oldNews-7\">[7]</a></sup> and the current recommended BOINC program version is 6.2.<sup id=\"cite_ref-BOINCClient_5-1\" class=\"reference\"><a href=\"#cite_note-BOINCClient-5\">[5]</a></sup> Standard <a href=\"/wiki/HTTP\" title=\"HTTP\">HTTP</a> (<a href=\"/wiki/TCP_and_UDP_port\" class=\"mw-redirect\" title=\"TCP and UDP port\">port</a> 80) is used for communication between the user's BOINC client and the Rosetta@home servers at the University of Washington; <a href=\"/wiki/HTTPS\" title=\"HTTPS\">HTTPS</a> (port 443) is used during password exchange. Remote and local control of the BOINC client use port 31416 and port 1043, which might need to be specifically unblocked if they are behind a <a href=\"/wiki/Firewall\" class=\"mw-disambig\" title=\"Firewall\">firewall</a>.<sup id=\"cite_ref-8\" class=\"reference\"><a href=\"#cite_note-8\">[8]</a></sup> <a href=\"/wiki/BOINC_client-server_technology\" class=\"mw-redirect\" title=\"BOINC client-server technology\">Workunits</a> containing data on individual proteins are distributed from servers located in the Baker lab at the <a href=\"/wiki/University_of_Washington\" title=\"University of Washington\">University of Washington</a> to volunteers' computers, which then calculate a structure prediction for the assigned protein. To avoid duplicate structure predictions on a given protein, each workunit is initialized with a <a href=\"/wiki/Random_seed\" title=\"Random seed\">random number seed</a>. This gives each prediction a unique trajectory of descent along the protein's <a href=\"/wiki/Energy_landscape\" class=\"mw-redirect\" title=\"Energy landscape\">energy landscape</a>.<sup id=\"cite_ref-9\" class=\"reference\"><a href=\"#cite_note-9\">[9]</a></sup> Protein structure predictions from Rosetta@home are approximations of a <a href=\"/wiki/Maxima_and_minima\" class=\"mw-redirect\" title=\"Maxima and minima\">global minimum</a> in a given protein's energy landscape. That global minimum represents the most energetically favorable conformation of the protein, i.e. its <a href=\"/wiki/Native_state\" title=\"Native state\">native state</a>.\n</p>\n<figure class=\"mw-default-size mw-halign-right\" typeof=\"mw:File/Thumb\"><a href=\"/wiki/File:R@H_v1.32_screensaver.png\" class=\"mw-file-description\"><img src=\"//upload.wikimedia.org/wikipedia/en/thumb/9/9f/R%40H_v1.32_screensaver.png/220px-R%40H_v1.32_screensaver.png\" decoding=\"async\" width=\"220\" height=\"148\" class=\"mw-file-element\" srcset=\"//upload.wikimedia.org/wikipedia/en/thumb/9/9f/R%40H_v1.32_screensaver.png/330px-R%40H_v1.32_screensaver.png 1.5x, //upload.wikimedia.org/wikipedia/en/9/9f/R%40H_v1.32_screensaver.png 2x\" data-file-width=\"384\" data-file-height=\"259\" /></a><figcaption>Rosetta@home screensaver, showing the progress of a structure prediction for a synthetic <a href=\"/wiki/Ubiquitin\" title=\"Ubiquitin\">ubiquitin</a> protein (PDB ID: 1ogw)</figcaption></figure>\n<p>A primary feature of the Rosetta@home <a href=\"/wiki/Graphical_user_interface\" title=\"Graphical user interface\">graphical user interface</a> (GUI) is a <a href=\"/wiki/Screensaver\" title=\"Screensaver\">screensaver</a> which shows a current <a href=\"/wiki/BOINC_client-server_technology\" class=\"mw-redirect\" title=\"BOINC client-server technology\">workunit</a>'s progress during the simulated <a href=\"/wiki/Protein_folding\" title=\"Protein folding\">protein folding</a> process. In the upper-left of the current screensaver, the target protein is shown adopting different shapes (conformations) in its search for the lowest energy structure. Depicted immediately to the right is the structure of the most recently accepted. On the upper right the lowest energy conformation of the current decoy is shown; below that is the true, or native, structure of the protein if it has already been determined. Three graphs are included in the screensaver. Towards the middle of it a graph for the accept model's <a href=\"/wiki/Thermodynamic_free_energy\" title=\"Thermodynamic free energy\">free energy</a> is displayed, which fluctuates as the accepted model changes. A graph of the accepted model's <a href=\"/wiki/Root_mean_square_deviation\" title=\"Root mean square deviation\">root mean square deviation</a> (RMSD), which measures how structurally similar the accepted model is to the native model, is shown far right. On the right of the accepted energy graph and below the RMSD graph, the results from these two functions are used to produce an energy vs. RMSD plot as the model is progressively refined.<sup id=\"cite_ref-10\" class=\"reference\"><a href=\"#cite_note-10\">[10]</a></sup>\n{{unblock|<strong class=\"error\">You are using this template in the wrong namespace. Use this template on <a href=\"/wiki/Special:MyTalk\" title=\"Special:MyTalk\">your talk page</a> instead.</strong>}\nLike all BOINC projects, Rosetta@home runs in the background of the user's computer using idle computer power, either at or before logging in to an account on the host <a href=\"/wiki/Operating_system\" title=\"Operating system\">operating system</a>. Rosetta@home frees resources from the CPU as they are required by other applications so that normal computer usage is unaffected. To minimize power consumption or heat production from a computer running at sustained capacity, the maximum percentage of CPU resources that Rosetta@home is allowed to use can be specified through a user's account preferences. The times of day during which Rosetta@home is allowed to do work can also be adjusted, along with many other preferences, through a user's account settings. \n</p><p>Rosetta, the software that runs on the Rosetta@home network, was rewritten in <a href=\"/wiki/C%2B%2B\" title=\"C++\">C++</a> to allow easier development than that offered by its original version, which was written in <a href=\"/wiki/Fortran\" title=\"Fortran\">Fortran</a>. This new version is <a href=\"/wiki/Object-oriented\" class=\"mw-redirect\" title=\"Object-oriented\">object-oriented</a>, and was released on February 8, 2008.<sup id=\"cite_ref-oldNews_7-1\" class=\"reference\"><a href=\"#cite_note-oldNews-7\">[7]</a></sup><sup id=\"cite_ref-11\" class=\"reference\"><a href=\"#cite_note-11\">[11]</a></sup> Development of the Rosetta code is done by Rosetta Commons.<sup id=\"cite_ref-rosettaCommons_12-0\" class=\"reference\"><a href=\"#cite_note-rosettaCommons-12\">[12]</a></sup> The software is freely licensed to the academic community and available to pharmaceutical companies for a fee.<sup id=\"cite_ref-rosettaCommons_12-1\" class=\"reference\"><a href=\"#cite_note-rosettaCommons-12\">[12]</a></sup>\n</p>\n<h2><span class=\"mw-headline\" id=\"Project_significance\">Project significance</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=2\" title=\"Edit section: Project significance\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1033289096\"><div role=\"note\" class=\"hatnote navigation-not-searchable\">Further information: [[:<a href=\"/wiki/Protein_structure_prediction\" title=\"Protein structure prediction\">Protein structure prediction</a>, <a href=\"/wiki/Protein_docking\" class=\"mw-redirect\" title=\"Protein docking\">Protein docking</a>, <a href=\"/wiki/Protein_design\" title=\"Protein design\">Protein design</a>]]</div>\n<p>With the proliferation of <a href=\"/wiki/List_of_sequenced_eukaryotic_genomes\" title=\"List of sequenced eukaryotic genomes\">genome sequencing projects</a>, scientists can infer the amino acid sequence, or <a href=\"/wiki/Primary_structure\" class=\"mw-redirect\" title=\"Primary structure\">primary structure</a>, of many proteins that carry out functions within the cell. To better understand a protein's function and aid in <a href=\"/wiki/Drug_design#Rational_drug_design\" title=\"Drug design\">rational drug design</a>, scientists need to know the protein's three-dimensional <a href=\"/wiki/Tertiary_structure\" class=\"mw-redirect\" title=\"Tertiary structure\">tertiary structure</a>.\n</p>\n<figure class=\"mw-default-size mw-halign-left\" typeof=\"mw:File/Thumb\"><a href=\"/wiki/File:T0281-bakerprediction_overlay.png\" class=\"mw-file-description\"><img src=\"//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/T0281-bakerprediction_overlay.png/220px-T0281-bakerprediction_overlay.png\" decoding=\"async\" width=\"220\" height=\"234\" class=\"mw-file-element\" srcset=\"//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/T0281-bakerprediction_overlay.png/330px-T0281-bakerprediction_overlay.png 1.5x, //upload.wikimedia.org/wikipedia/commons/2/2b/T0281-bakerprediction_overlay.png 2x\" data-file-width=\"332\" data-file-height=\"353\" /></a><figcaption>CASP6 target T0281, the first <i>ab initio</i> protein structure prediction to approach atomic-level resolution. Rosetta produced a model for T0281 (<a href=\"/wiki/Protein_structural_alignment\" class=\"mw-redirect\" title=\"Protein structural alignment\">superpositioned</a> in magenta) 1.5 <a href=\"/wiki/%C3%85\" title=\"\u00c5\">\u00c5</a> <a href=\"/wiki/RMSD\" class=\"mw-redirect\" title=\"RMSD\">RMSD</a> from the crystal structure (blue).</figcaption></figure>\n<p>Protein 3D structures are currently determined experimentally through <a href=\"/wiki/X-ray_crystallography\" title=\"X-ray crystallography\">X-ray crystallography</a> or <a href=\"/wiki/Nuclear_magnetic_resonance\" title=\"Nuclear magnetic resonance\">nuclear magnetic resonance</a> (NMR) spectroscopy. The process is slow (it can take weeks or even months to figure out how to crystallize a protein for the first time) and comes at high cost (around $100,000 USD per protein).<sup id=\"cite_ref-13\" class=\"reference\"><a href=\"#cite_note-13\">[13]</a></sup> Unfortunately, the rate at which new sequences are discovered far exceeds the rate of structure determination \u2013 out of more than 7,400,000 protein sequences available in the <a href=\"/wiki/National_Center_for_Biotechnology_Information\" title=\"National Center for Biotechnology Information\">NCBI</a> non-redundant (nr) protein database, less than 52,000 proteins' 3D structures have been solved and deposited in the <a href=\"/wiki/Protein_Data_Bank\" title=\"Protein Data Bank\">Protein Data Bank</a>, the main repository for structural information on proteins.<sup id=\"cite_ref-14\" class=\"reference\"><a href=\"#cite_note-14\">[14]</a></sup> One of the main goals of Rosetta@home is to predict protein structures with the same accuracy as existing methods, but in a way that requires significantly less time and money. Rosetta@home also develops methods to determine the structure and docking of membrane proteins (e.g., <a href=\"/wiki/GPCR\" class=\"mw-redirect\" title=\"GPCR\">GPCRs</a>),<sup id=\"cite_ref-15\" class=\"reference\"><a href=\"#cite_note-15\">[15]</a></sup> which are exceptionally difficult to analyze with traditional techniques like X-ray crystallography and NMR spectroscopy, yet represent the majority of targets for modern drugs.\n</p><p>Progress in protein structure prediction is evaluated in the biannual <a href=\"/wiki/Critical_Assessment_of_Techniques_for_Protein_Structure_Prediction\" class=\"mw-redirect\" title=\"Critical Assessment of Techniques for Protein Structure Prediction\">Critical Assessment of Techniques for Protein Structure Prediction</a> (CASP) experiment, in which researchers from around the world attempt to derive a protein's structure from the protein's amino acid sequence. High scoring groups in this sometimes competitive experiment are considered the <i><a href=\"/wiki/De_facto\" title=\"De facto\">de facto</a></i> standard-bearers for what is the state of the art in protein structure prediction. Rosetta, the program on which Rosetta@home is based, has been used since CASP 5 in 2002. In the 2004 CASP 6 experiment, Rosetta made history by being the first to produce a close to atomic-level resolution, <i><a href=\"/wiki/Protein_folding#Computational_prediction_of_protein_tertiary_structure\" title=\"Protein folding\">ab initio</a></i> protein structure prediction in its submitted model for CASP target T0281.<sup id=\"cite_ref-R@H_ResearchOverview_16-0\" class=\"reference\"><a href=\"#cite_note-R@H_ResearchOverview-16\">[16]</a></sup> <i>Ab initio</i> modeling is considered an especially difficult category of protein structure prediction, as it does not use information from <a href=\"/wiki/Structural_alignment\" title=\"Structural alignment\">structural homology</a> and must rely on information from <a href=\"/wiki/Multiple_sequence_alignment\" title=\"Multiple sequence alignment\">sequence homology</a> and modeling physical interactions within the protein. Rosetta@home has been used in CASP since 2006, where it was among the top predictors in every category of structure prediction in CASP 7.<sup id=\"cite_ref-17\" class=\"reference\"><a href=\"#cite_note-17\">[17]</a></sup><sup id=\"cite_ref-18\" class=\"reference\"><a href=\"#cite_note-18\">[18]</a></sup><sup id=\"cite_ref-CASP7Assessment_19-0\" class=\"reference\"><a href=\"#cite_note-CASP7Assessment-19\">[19]</a></sup> These high quality predictions were enabled by the computing power made available by Rosetta@home volunteers.<sup id=\"cite_ref-CASP7_baker_20-0\" class=\"reference\"><a href=\"#cite_note-CASP7_baker-20\">[20]</a></sup> Increasing computational power allows Rosetta@home to sample more regions of <a href=\"/wiki/Configuration_space\" class=\"mw-disambig\" title=\"Configuration space\"> conformation space</a> (the possible shapes a protein can assume), which, according to <a href=\"/wiki/Levinthal%27s_paradox\" title=\"Levinthal's paradox\">Levinthal's paradox</a>, is predicted to <a href=\"/wiki/Computational_complexity_theory\" title=\"Computational complexity theory\">increase exponentially</a> with protein length.\n</p><p>Rosetta@home is also used in <a href=\"/wiki/Protein-protein_docking\" class=\"mw-redirect\" title=\"Protein-protein docking\">protein docking</a> prediction, which determines the structure of multiple <a href=\"/wiki/Protein_complex\" title=\"Protein complex\">complexed proteins</a>, or <a href=\"/wiki/Quaternary_structure\" class=\"mw-redirect\" title=\"Quaternary structure\">quaternary structure</a>. This type of <a href=\"/wiki/Protein-protein_interaction\" class=\"mw-redirect\" title=\"Protein-protein interaction\">protein interaction</a> affects many cellular functions, including antigen\u2013antibody and enzyme\u2013inhibitor binding and cellular import and export. Determining these interactions is critical for <a href=\"/wiki/Drug_design\" title=\"Drug design\">drug design</a>. Rosetta is used in the <a href=\"/wiki/Critical_Assessment_of_Prediction_of_Interactions\" title=\"Critical Assessment of Prediction of Interactions\">Critical Assessment of Prediction of Interactions</a> (CAPRI) experiment, which evaluates the state of the protein docking field similar to how CASP gauges progress in protein structure prediction. The computing power made available by Rosetta@home's project volunteers has been cited as a major factor in Rosetta's performance in CAPRI, where its docking predictions have been among the most accurate and complete.<sup id=\"cite_ref-CAPRI3_1_21-0\" class=\"reference\"><a href=\"#cite_note-CAPRI3_1-21\">[21]</a></sup>\n</p><p>In early 2008, Rosetta was used to computationally design a protein with a function never before observed in nature.<sup id=\"cite_ref-RetroAldol_22-0\" class=\"reference\"><a href=\"#cite_note-RetroAldol-22\">[22]</a></sup> This was inspired in part by the retraction of a high-profile paper from 2004 which originally described the computational design of a protein with improved enzymatic activity compared to its natural form.<sup id=\"cite_ref-23\" class=\"reference\"><a href=\"#cite_note-23\">[23]</a></sup> The 2008 <a href=\"/wiki/Academic_publishing#Scholarly_paper\" title=\"Academic publishing\">research paper</a> from David Baker's group describing how the protein was made, which cited Rosetta@home for the computational resources it made available, represented an important <a href=\"/wiki/Proof_of_concept\" title=\"Proof of concept\">proof of concept</a> for this protein design method.<sup id=\"cite_ref-RetroAldol_22-1\" class=\"reference\"><a href=\"#cite_note-RetroAldol-22\">[22]</a></sup> This type of protein design could have future applications in drug discovery, <a href=\"/wiki/Green_chemistry\" title=\"Green chemistry\">green chemistry</a>, and <a href=\"/wiki/Bioremediation\" title=\"Bioremediation\">bioremediation</a>.<sup id=\"cite_ref-RetroAldol_22-2\" class=\"reference\"><a href=\"#cite_note-RetroAldol-22\">[22]</a></sup>\n</p>\n<h2><span class=\"mw-headline\" id=\"Disease-related_research\">Disease-related research</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=3\" title=\"Edit section: Disease-related research\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<p>In addition to basic research in predicting protein structure, docking and design, Rosetta@home is also used in immediate disease-related research.<sup id=\"cite_ref-medicalRelevance_24-0\" class=\"reference\"><a href=\"#cite_note-medicalRelevance-24\">[24]</a></sup> Numerous minor research projects are described in David Baker's Rosetta@home journal.<sup id=\"cite_ref-25\" class=\"reference\"><a href=\"#cite_note-25\">[25]</a></sup> \n</p>\n<h3><span id=\"Alzheimer.27s_disease\"></span><span class=\"mw-headline\" id=\"Alzheimer's_disease\">Alzheimer's disease</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=4\" title=\"Edit section: Alzheimer's disease\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>A component of the Rosetta software suite, RosettaDesign, was used to accurately predict which regions of amyloidogenic proteins were most likely to make <a href=\"/wiki/Amyloid\" title=\"Amyloid\"> amyloid-like fibrils</a>.<sup id=\"cite_ref-26\" class=\"reference\"><a href=\"#cite_note-26\">[26]</a></sup> By taking hexapeptides (six amino acid-long fragments) of a protein of interest and selecting the lowest energy match to a structure similar to that of a known fibril forming hexapeptide, RosettaDesign was able to identify peptides twice as likely to form fibrils as are random proteins.<sup id=\"cite_ref-27\" class=\"reference\"><a href=\"#cite_note-27\">[27]</a></sup> Rosetta@home was used to in the same study to predict structures for <a href=\"/wiki/Amyloid_beta\" title=\"Amyloid beta\">amyloid beta</a>, a fibril-forming protein that has been postulated to cause <a href=\"/wiki/Alzheimer%27s_disease\" title=\"Alzheimer's disease\">Alzheimer's disease</a>.<sup id=\"cite_ref-28\" class=\"reference\"><a href=\"#cite_note-28\">[28]</a></sup> Preliminary but as yet unpublished results have been produced on Rosetta-designed proteins that may prevent fibrils from forming, although it is unknown whether it can prevent the disease.<sup id=\"cite_ref-29\" class=\"reference\"><a href=\"#cite_note-29\">[29]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"Anthrax\">Anthrax</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=5\" title=\"Edit section: Anthrax\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>Another component of Rosetta, RosettaDock,<sup id=\"cite_ref-30\" class=\"reference\"><a href=\"#cite_note-30\">[30]</a></sup><sup id=\"cite_ref-31\" class=\"reference\"><a href=\"#cite_note-31\">[31]</a></sup><sup id=\"cite_ref-Schueler-Furman_32-0\" class=\"reference\"><a href=\"#cite_note-Schueler-Furman-32\">[32]</a></sup> was used in conjunction with experimental methods to model interactions between three proteins \u2013 lethal factor (LF), edema factor (EF) and protective antigen (PA) \u2013 that make up <a href=\"/wiki/Anthrax_toxin\" title=\"Anthrax toxin\">anthrax toxin</a>. The computational model accurately predicted docking between LF and PA, helping to establish which <a href=\"/wiki/Protein_domain\" title=\"Protein domain\">domains</a> of the respective proteins are involved in the LF\u2013PA complex. This insight was eventually used in research resulting in improved anthrax vaccines.<sup id=\"cite_ref-33\" class=\"reference\"><a href=\"#cite_note-33\">[33]</a></sup><sup id=\"cite_ref-34\" class=\"reference\"><a href=\"#cite_note-34\">[34]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"Herpes_simplex_virus_1\">Herpes simplex virus 1</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=6\" title=\"Edit section: Herpes simplex virus 1\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>RosettaDock was also used to model docking between an <a href=\"/wiki/Antibody\" title=\"Antibody\">antibody</a> (<a href=\"/wiki/Immunoglobulin_G\" title=\"Immunoglobulin G\">immunoglobulin G</a>) and a surface protein expressed by <a href=\"/wiki/Herpes_simplex_virus_1\" class=\"mw-redirect\" title=\"Herpes simplex virus 1\">herpes simplex virus 1</a> (HSV-1) which serves to degrade the antiviral antibody. The protein complex predicted by RosettaDock closely agreed with the particularly difficult-to-obtain experimental models, leading researchers to conclude that the docking method has potential in addressing some of the problems that X-ray crystallography has with modeling protein-protein interfaces.<sup id=\"cite_ref-35\" class=\"reference\"><a href=\"#cite_note-35\">[35]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"HIV\">HIV</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=7\" title=\"Edit section: HIV\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>As part of research funded by a $19.4 million dollar grant by the <a href=\"/wiki/Bill_and_Melinda_Gates_Foundation\" class=\"mw-redirect\" title=\"Bill and Melinda Gates Foundation\">Bill and Melinda Gates Foundation</a>,<sup id=\"cite_ref-36\" class=\"reference\"><a href=\"#cite_note-36\">[36]</a></sup> Rosetta@home has been used in designing multiple possible vaccines for <a href=\"/wiki/HIV\" title=\"HIV\">human immunodeficiency virus</a> (HIV).<sup id=\"cite_ref-37\" class=\"reference\"><a href=\"#cite_note-37\">[37]</a></sup><sup id=\"cite_ref-38\" class=\"reference\"><a href=\"#cite_note-38\">[38]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"Malaria\">Malaria</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=8\" title=\"Edit section: Malaria\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>In research involved with the <a href=\"/wiki/Grand_Challenges_in_Global_Health\" title=\"Grand Challenges in Global Health\">Grand Challenges in Global Health</a> initiative,<sup id=\"cite_ref-39\" class=\"reference\"><a href=\"#cite_note-39\">[39]</a></sup> Rosetta has also been used to computationally design novel <a href=\"/wiki/Intragenomic_conflict#Homing_endonuclease_genes\" title=\"Intragenomic conflict\">homing endonuclease</a> proteins, which could eradicate <i><a href=\"/wiki/Anopheles_gambiae\" title=\"Anopheles gambiae\">Anopheles gambiae</a></i> or otherwise render the mosquito unable to transmit <a href=\"/wiki/Malaria\" title=\"Malaria\">malaria</a>.<sup id=\"cite_ref-40\" class=\"reference\"><a href=\"#cite_note-40\">[40]</a></sup> Being able to model and alter protein\u2013DNA interactions specifically, like those of homing endonucleases, gives computational protein design methods like Rosetta an important role in <a href=\"/wiki/Gene_therapy\" title=\"Gene therapy\">gene therapy</a> (which includes possible <a href=\"/wiki/Cancer\" title=\"Cancer\">cancer</a> treatments).<sup id=\"cite_ref-medicalRelevance_24-1\" class=\"reference\"><a href=\"#cite_note-medicalRelevance-24\">[24]</a></sup><sup id=\"cite_ref-41\" class=\"reference\"><a href=\"#cite_note-41\">[41]</a></sup>\n</p>\n<h2><span class=\"mw-headline\" id=\"Development_history_and_branches\">Development history and branches</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=9\" title=\"Edit section: Development history and branches\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<p>Originally introduced by the Baker laboratory in 1998 as an <i>ab initio</i> approach to structure prediction,<sup id=\"cite_ref-42\" class=\"reference\"><a href=\"#cite_note-42\">[42]</a></sup> Rosetta has since branched into several development streams and distinct services. More than seven years after Rosetta's first appearance, the Rosetta@home project was released (i.e. announced as no longer <a href=\"/wiki/Development_stage#Beta\" class=\"mw-redirect\" title=\"Development stage\">beta</a>) on October 6, 2005.<sup id=\"cite_ref-oldNews_7-2\" class=\"reference\"><a href=\"#cite_note-oldNews-7\">[7]</a></sup> Many of the graduate students and other researchers involved in Rosetta's initial development have since moved to other universities and research institutions, and subsequently enhanced different parts of the Rosetta project.\n</p>\n<h3><span class=\"mw-headline\" id=\"RosettaDesign\">RosettaDesign</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=10\" title=\"Edit section: RosettaDesign\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<figure class=\"mw-default-size mw-halign-right\" typeof=\"mw:File/Thumb\"><a href=\"/wiki/File:TOP7-rosetta_superposition.png\" class=\"mw-file-description\"><img src=\"//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/TOP7-rosetta_superposition.png/220px-TOP7-rosetta_superposition.png\" decoding=\"async\" width=\"220\" height=\"208\" class=\"mw-file-element\" srcset=\"//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/TOP7-rosetta_superposition.png/330px-TOP7-rosetta_superposition.png 1.5x, //upload.wikimedia.org/wikipedia/commons/b/b0/TOP7-rosetta_superposition.png 2x\" data-file-width=\"435\" data-file-height=\"411\" /></a><figcaption>Superposition of Rosetta-designed model (red) for TOP7 onto its X-ray crystal structure (blue, PDB ID: 1QYS)</figcaption></figure>\n<p>RosettaDesign, a computational approach to protein design based on Rosetta, began in 2000 with a study in redesigning the folding pathway of <a href=\"/wiki/Protein_G\" title=\"Protein G\">Protein G</a>.<sup id=\"cite_ref-43\" class=\"reference\"><a href=\"#cite_note-43\">[43]</a></sup> In 2002 RosettaDesign was used to design TOP7, a 93-amino acid long <a href=\"/wiki/%CE%91/%CE%B2_proteins\" class=\"mw-redirect\" title=\"\u0391/\u03b2 proteins\">α/β</a> protein that had an overall <a href=\"/wiki/Structural_Classification_of_Proteins\" class=\"mw-redirect\" title=\"Structural Classification of Proteins\">fold</a> never before recorded in nature. This new conformation was predicted by Rosetta to within 1.2 <a href=\"/wiki/%C3%85\" title=\"\u00c5\">\u00c5</a> <a href=\"/wiki/RMSD\" class=\"mw-redirect\" title=\"RMSD\">RMSD</a> of the structure determined by <a href=\"/wiki/X-ray_crystallography\" title=\"X-ray crystallography\">X-ray crystallography</a>, representing an unusually accurate structure prediction.<sup id=\"cite_ref-44\" class=\"reference\"><a href=\"#cite_note-44\">[44]</a></sup> Rosetta and RosettaDesign earned widespread recognition by being the first to design and accurately predict the structure of a novel protein of such length, as reflected by the 2002 paper describing the dual approach prompting two positive letters in the journal <a href=\"/wiki/Science_(journal)\" title=\"Science (journal)\"><i>Science</i></a>,<sup id=\"cite_ref-45\" class=\"reference\"><a href=\"#cite_note-45\">[45]</a></sup><sup id=\"cite_ref-46\" class=\"reference\"><a href=\"#cite_note-46\">[46]</a></sup> and being cited by more than 240 other scientific articles.<sup id=\"cite_ref-47\" class=\"reference\"><a href=\"#cite_note-47\">[47]</a></sup> The visible product of that research, TOP7, was featured as the <a href=\"/wiki/Protein_Data_Bank\" title=\"Protein Data Bank\">Protein Data Bank</a>'s 'Molecule of the Month' in October 2006;<sup id=\"cite_ref-48\" class=\"reference\"><a href=\"#cite_note-48\">[48]</a></sup> a <a href=\"/wiki/Structural_alignment\" title=\"Structural alignment\">superposition</a> of the respective cores (residues 60-79) of its predicted and X-ray crystal structures are also featured in the Rosetta@home logo.<sup id=\"cite_ref-R@H_ResearchOverview_16-1\" class=\"reference\"><a href=\"#cite_note-R@H_ResearchOverview-16\">[16]</a></sup> \n</p><p>Brian Kuhlman, who obtained his PhD under <a href=\"/wiki/David_Baker_(biochemist)\" title=\"David Baker (biochemist)\">David Baker</a> and now researches protein design with Rosetta in his own laboratory at the <a href=\"/wiki/University_of_North_Carolina,_Chapel_Hill\" class=\"mw-redirect\" title=\"University of North Carolina, Chapel Hill\">University of North Carolina, Chapel Hill</a>,<sup id=\"cite_ref-49\" class=\"reference\"><a href=\"#cite_note-49\">[49]</a></sup> offers RosettaDesign as an online service.<sup id=\"cite_ref-50\" class=\"reference\"><a href=\"#cite_note-50\">[50]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"RosettaDock\">RosettaDock</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=11\" title=\"Edit section: RosettaDock\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>RosettaDock was added to the Rosetta software suite during the first <a href=\"/wiki/CAPRI\" class=\"mw-redirect\" title=\"CAPRI\">CAPRI</a> experiment in 2002 as the Baker laboratory's <a href=\"/wiki/Algorithm\" title=\"Algorithm\">algorithm</a> for <a href=\"/wiki/Protein-protein_docking\" class=\"mw-redirect\" title=\"Protein-protein docking\">protein-protein docking</a> prediction.<sup id=\"cite_ref-CAPRI_1_51-0\" class=\"reference\"><a href=\"#cite_note-CAPRI_1-51\">[51]</a></sup> In that experiment, RosettaDock made a high-accuracy prediction for the docking between <a href=\"/wiki/Streptococcus_pyogenes#Virulence_factors\" title=\"Streptococcus pyogenes\">streptococcal pyogenic exotoxin A</a> and a <a href=\"/wiki/T_cell_receptor#Structural_characteristics_of_the_TCR\" class=\"mw-redirect\" title=\"T cell receptor\">T cell-receptor β-chain</a>, and a medium accuracy prediction for a complex between <a href=\"/wiki/Porcine\" class=\"mw-redirect\" title=\"Porcine\">porcine</a> <a href=\"/wiki/%CE%91-amylase\" class=\"mw-redirect\" title=\"\u0391-amylase\">\u03b1-amylase</a> and a <a href=\"/wiki/Camelid\" class=\"mw-redirect\" title=\"Camelid\">camelid</a> <a href=\"/wiki/Antibody\" title=\"Antibody\">antibody</a>. While the RosettaDock method only made two acceptably accurate predictions out of seven possible, this was enough to rank it seventh out of nineteen prediction methods in the first CAPRI assessment.<sup id=\"cite_ref-CAPRI_1_51-1\" class=\"reference\"><a href=\"#cite_note-CAPRI_1-51\">[51]</a></sup>\n</p><p>Development of RosettaDock diverged into two branches for subsequent CAPRI rounds as Jeffrey Gray, who laid the groundwork for RosettaDock while at the <a href=\"/wiki/University_of_Washington\" title=\"University of Washington\">University of Washington</a>, continued working on the method in his new position at <a href=\"/wiki/John_Hopkins_University\" class=\"mw-redirect\" title=\"John Hopkins University\">John Hopkins University</a>. Members of the Baker laboratory further developed RosettaDock in Gray's absence. The two versions differed slightly in side-chain modeling, decoy selection and other areas.<sup id=\"cite_ref-Schueler-Furman_32-1\" class=\"reference\"><a href=\"#cite_note-Schueler-Furman-32\">[32]</a></sup><sup id=\"cite_ref-52\" class=\"reference\"><a href=\"#cite_note-52\">[52]</a></sup> Despite these differences, both the Baker and Gray methods performed well in the second CAPRI assessment, placing fifth and seventh respectively out of 30 predictor groups.<sup id=\"cite_ref-53\" class=\"reference\"><a href=\"#cite_note-53\">[53]</a></sup> Jeffrey Gray's RosettaDock server is available as a free docking prediction service for non-commercial use.<sup id=\"cite_ref-54\" class=\"reference\"><a href=\"#cite_note-54\">[54]</a></sup>\n</p><p>In October 2006, RosettaDock was integrated into Rosetta@home. The method used a fast, crude docking model phase using only the <a href=\"/wiki/Protein_structural_alignment#Types_of_comparisons\" class=\"mw-redirect\" title=\"Protein structural alignment\">protein backbone</a>. This was followed by a slow full-atom refinement phase in which the orientation of the two interacting proteins relative to each other, and side-chain interactions at the protein-protein interface, were simultaneously optimized to find the lowest energy conformation.<sup id=\"cite_ref-55\" class=\"reference\"><a href=\"#cite_note-55\">[55]</a></sup> The vastly increased computational power afforded by the Rosetta@home network, in combination with revised \"fold-tree\" representations for backbone flexibility and <a href=\"/wiki/Loop_modeling\" title=\"Loop modeling\">loop modeling</a>, made RosettaDock sixth out of 63 prediction groups in the third CAPRI assessment.<sup id=\"cite_ref-CAPRI3_4-1\" class=\"reference\"><a href=\"#cite_note-CAPRI3-4\">[4]</a></sup><sup id=\"cite_ref-CAPRI3_1_21-1\" class=\"reference\"><a href=\"#cite_note-CAPRI3_1-21\">[21]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"Robetta\">Robetta</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=12\" title=\"Edit section: Robetta\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>The Robetta server is an automated protein structure prediction service offered by the Baker laboratory for non-commercial <i>ab initio</i> and comparative modeling.<sup id=\"cite_ref-56\" class=\"reference\"><a href=\"#cite_note-56\">[56]</a></sup> It has participated as an automated prediction server in the biannual <a href=\"/wiki/CASP\" title=\"CASP\">CASP</a> experiments since CASP 5 in 2002, performing among the best in the automated server prediction category.<sup id=\"cite_ref-57\" class=\"reference\"><a href=\"#cite_note-57\">[57]</a></sup> Robetta has since competed in CASP 6 and 7, where it did better than average among both automated server and human predictor groups.<sup id=\"cite_ref-CASP7Assessment_19-1\" class=\"reference\"><a href=\"#cite_note-CASP7Assessment-19\">[19]</a></sup><sup id=\"cite_ref-58\" class=\"reference\"><a href=\"#cite_note-58\">[58]</a></sup><sup id=\"cite_ref-59\" class=\"reference\"><a href=\"#cite_note-59\">[59]</a></sup>\n</p><p>In modeling protein structure as of CASP 6, Robetta first searches for structural homologs using <a href=\"/wiki/BLAST\" class=\"mw-redirect mw-disambig\" title=\"BLAST\">BLAST</a>, <a href=\"/wiki/PSI-BLAST\" class=\"mw-redirect\" title=\"PSI-BLAST\">PSI-BLAST</a>, and <a href=\"/wiki/3D-Jury\" title=\"3D-Jury\">3D-Jury</a>, then parses the target sequence into its individual <a href=\"/wiki/Protein_domain\" title=\"Protein domain\">domains</a>, or independently folding units of proteins, by matching the sequence to structural families in the <a href=\"/wiki/Pfam\" title=\"Pfam\"> Pfam database</a>. Domains with structural homologs then follow a \"template-based model\" (i.e., <a href=\"/wiki/Homology_modeling\" title=\"Homology modeling\">homology modeling</a>) protocol. Here, the Baker laboratory's in-house alignment program, K*sync, produces a group of sequence homologs, and each of these is modeled by the Rosetta <i>de novo</i> method to produce a decoy (possible structure). The final structure prediction is selected by taking the <a href=\"/wiki/Thermodynamic_free_energy\" title=\"Thermodynamic free energy\">lowest energy</a> model as determined by a low-resolution Rosetta energy function. For domains that have no detected structural homologs, a <i>de novo</i> protocol is followed in which the lowest energy model from a set of generated decoys is selected as the final prediction. These domain predictions are then connected together to investigate inter-domain, tertiary-level interactions within the protein. Finally, side-chain contributions are modeled using a protocol for <a href=\"/wiki/Monte_Carlo_method\" title=\"Monte Carlo method\">Monte Carlo</a> conformational search.<sup id=\"cite_ref-60\" class=\"reference\"><a href=\"#cite_note-60\">[60]</a></sup>\n</p><p>In CASP 8, Robetta was augmented to use Rosetta's high resolution all-atom refinement method,<sup id=\"cite_ref-61\" class=\"reference\"><a href=\"#cite_note-61\">[61]</a></sup> the absence of which was cited as the main cause for Robetta being less accurate than the Rosetta@home network in CASP 7.<sup id=\"cite_ref-CASP7_baker_20-1\" class=\"reference\"><a href=\"#cite_note-CASP7_baker-20\">[20]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"Foldit\">Foldit</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=13\" title=\"Edit section: Foldit\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>On May 9, 2008, after Rosetta@home users suggested an interactive version of the <a href=\"/wiki/Distributed_computing\" title=\"Distributed computing\">distributed computing</a> program, the Baker lab publicly released <a href=\"/wiki/Foldit\" title=\"Foldit\">Foldit</a>, an online protein structure prediction game based on the Rosetta platform.<sup id=\"cite_ref-62\" class=\"reference\"><a href=\"#cite_note-62\">[62]</a></sup> As of September 25, 2008, Foldit has over 59,000 registered users.<sup id=\"cite_ref-63\" class=\"reference\"><a href=\"#cite_note-63\">[63]</a></sup> The game gives users a set of controls (e.g. \"shake\", \"wiggle\", \"rebuild\") to manipulate the <a href=\"/wiki/Protein#Biochemistry\" title=\"Protein\">backbone</a> and amino acid <a href=\"/wiki/Side_chain\" title=\"Side chain\">side chains</a> of the target protein into more energetically favorable conformations. Users can work on solutions individually as \"soloists\" or collectively as \"evolvers\", accruing points under either category as they improve their structure predictions.<sup id=\"cite_ref-64\" class=\"reference\"><a href=\"#cite_note-64\">[64]</a></sup> Users can also individually compete with other users through a \"duel\" feature, in which the player with the lowest energy structure after 20 moves wins.\n</p>\n<h2><span class=\"mw-headline\" id=\"Comparison_to_similar_distributed_computing_projects\">Comparison to similar distributed computing projects</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=14\" title=\"Edit section: Comparison to similar distributed computing projects\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<p>There are several distributed computed projects which have study areas similar to those of Rosetta@home, but differ in their research approach:\n</p>\n<h3><span id=\"Folding.40home\"></span><span class=\"mw-headline\" id=\"Folding@home\">Folding@home</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=15\" title=\"Edit section: Folding@home\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>Of all the major distributed computing projects involved in protein research, <a href=\"/wiki/Folding@home\" title=\"Folding@home\">Folding@home</a> is the only one not to use the <a href=\"/wiki/BOINC\" class=\"mw-redirect\" title=\"BOINC\">BOINC</a> platform.<sup id=\"cite_ref-65\" class=\"reference\"><a href=\"#cite_note-65\">[65]</a></sup> Both Rosetta@home and Folding@home research protein misfolding diseases (e.g. Alzheimer's disease), but Folding@home does so much more exclusively.<sup id=\"cite_ref-66\" class=\"reference\"><a href=\"#cite_note-66\">[66]</a></sup> Instead of using structure- or design-based methods to predict <a href=\"/wiki/Amyloid\" title=\"Amyloid\">amyloid</a> behavior, for example, Folding@home uses <a href=\"/wiki/Molecular_dynamics\" title=\"Molecular dynamics\">molecular dynamics</a> to model how proteins fold (or potentially misfold, and subsequently aggregate).<sup id=\"cite_ref-67\" class=\"reference\"><a href=\"#cite_note-67\">[67]</a></sup> In other words, Folding@home's strength is modeling the process of protein folding, while Rosetta@home's strength is computational protein design and prediction of protein structure and docking. The two projects also differ significantly in their computing power and host diversity. Averaging about 4.2 <a href=\"/wiki/PetaFLOPS\" class=\"mw-redirect\" title=\"PetaFLOPS\">petaFLOPS</a> (4200 teraFLOPS) with a host base that includes the <a href=\"/wiki/Playstation_3\" class=\"mw-redirect\" title=\"Playstation 3\">Playstation 3</a> and <a href=\"/wiki/Graphics_processing_unit\" title=\"Graphics processing unit\">graphics processing units</a>,<sup id=\"cite_ref-68\" class=\"reference\"><a href=\"#cite_note-68\">[68]</a></sup> Folding@home has more than a 55-fold advantage in computing power over Rosetta@home, which averages 76 teraFLOPS with a host base consisting only of PC-based <a href=\"/wiki/CPU\" class=\"mw-redirect\" title=\"CPU\">CPUs</a>.<sup id=\"cite_ref-BOINCstats_RosettaOverview_2-1\" class=\"reference\"><a href=\"#cite_note-BOINCstats_RosettaOverview-2\">[2]</a></sup>\n</p>\n<h3><span class=\"mw-headline\" id=\"World_Community_Grid\">World Community Grid</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=16\" title=\"Edit section: World Community Grid\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>Both Phase I and Phase II of the <a href=\"/wiki/Human_Proteome_Folding_Project\" title=\"Human Proteome Folding Project\">Human Proteome Folding Project</a> (HPF), a subproject of <a href=\"/wiki/World_Community_Grid\" title=\"World Community Grid\">World Community Grid</a>, have used the Rosetta program to make structural and functional annotations of various <a href=\"/wiki/Genomes\" class=\"mw-redirect\" title=\"Genomes\">genomes</a>.<sup id=\"cite_ref-69\" class=\"reference\"><a href=\"#cite_note-69\">[69]</a></sup><sup id=\"cite_ref-70\" class=\"reference\"><a href=\"#cite_note-70\">[70]</a></sup> Although he now uses it to create databases for biologists, Richard Bonneau, head scientist of the Human Proteome Folding Project, was active in the original development of Rosetta at David Baker's laboratory while obtaining his PhD.<sup id=\"cite_ref-71\" class=\"reference\"><a href=\"#cite_note-71\">[71]</a></sup> More information on the relationship between the HPF1, HPF2 and Rosetta@home can be found on Richard Bonneau's website.<sup id=\"cite_ref-72\" class=\"reference\"><a href=\"#cite_note-72\">[72]</a></sup>\n</p>\n<h3><span id=\"Predictor.40home\"></span><span class=\"mw-headline\" id=\"Predictor@home\">Predictor@home</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=17\" title=\"Edit section: Predictor@home\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h3>\n<p>Like Rosetta@home, <a href=\"/wiki/Predictor@home\" title=\"Predictor@home\">Predictor@home</a> specializes in protein structure prediction. Predictor@home also plans to develop new areas for its distributed computing platform in protein design and docking (using the <a href=\"/wiki/CHARMM\" title=\"CHARMM\">CHARMM</a> package for molecular dynamics),<sup id=\"cite_ref-73\" class=\"reference\"><a href=\"#cite_note-73\">[73]</a></sup> further likening it to Rosetta@home. While Rosetta@home uses the Rosetta program for its structure prediction, Predictor@home uses the dTASSER methodology.<sup id=\"cite_ref-74\" class=\"reference\"><a href=\"#cite_note-74\">[74]</a></sup>\n</p><p>Other protein related distributed computing projects on <a href=\"/wiki/BOINC\" class=\"mw-redirect\" title=\"BOINC\">BOINC</a> include <a href=\"/wiki/QMC@home\" class=\"mw-redirect\" title=\"QMC@home\">QMC@home</a>, <a href=\"/wiki/Docking@home\" class=\"mw-redirect\" title=\"Docking@home\">Docking@home</a>, <a href=\"/wiki/POEM@home\" class=\"mw-redirect\" title=\"POEM@home\">POEM@home</a>, <a href=\"/wiki/SIMAP\" class=\"mw-disambig\" title=\"SIMAP\">SIMAP</a>, and <a href=\"/wiki/TANPAKU\" class=\"mw-redirect\" title=\"TANPAKU\">TANPAKU</a>. RALPH@home, the Rosetta@home <a href=\"/wiki/Software_release_life_cycle#Alpha\" title=\"Software release life cycle\">alpha</a> project which tests new application versions, work units, and updates before they move on to Rosetta@home, runs on BOINC as well.<sup id=\"cite_ref-75\" class=\"reference\"><a href=\"#cite_note-75\">[75]</a></sup>\n</p>\n<h2><span class=\"mw-headline\" id=\"Volunteer_contributions\">Volunteer contributions</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=18\" title=\"Edit section: Volunteer contributions\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<p>Rosetta@home depends on computing power donated by individual project members for its research. As of November 30, 2008, over 47,000 users from 161 countries were active members of Rosetta@home, together contributing idle processor time from over 86,000 computers for a combined average performance of over 77 <a href=\"/wiki/TeraFLOPS\" class=\"mw-redirect\" title=\"TeraFLOPS\">teraFLOPS</a>.<sup id=\"cite_ref-BOINCstats_RosettaOverview_2-2\" class=\"reference\"><a href=\"#cite_note-BOINCstats_RosettaOverview-2\">[2]</a></sup>\n</p>\n<figure class=\"mw-default-size mw-halign-left\" typeof=\"mw:File/Thumb\"><a href=\"/wiki/File:Boincstats_R@H_CpD.png\" class=\"mw-file-description\"><img src=\"//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Boincstats_R%40H_CpD.png/220px-Boincstats_R%40H_CpD.png\" decoding=\"async\" width=\"220\" height=\"101\" class=\"mw-file-element\" srcset=\"//upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Boincstats_R%40H_CpD.png/330px-Boincstats_R%40H_CpD.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Boincstats_R%40H_CpD.png/440px-Boincstats_R%40H_CpD.png 2x\" data-file-width=\"817\" data-file-height=\"375\" /></a><figcaption><a href=\"/wiki/Bar_chart\" title=\"Bar chart\">Bar chart</a> showing cumulative credit per day for Rosetta@home over a 60-day period, indicating its computational power during the <a href=\"/wiki/CASP\" title=\"CASP\"> CASP 8</a> experiment</figcaption></figure>\n<p>Users are granted <a href=\"/wiki/BOINC_Credit_System\" title=\"BOINC Credit System\">BOINC credits</a> as a measure of their contribution. The credit granted for each workunit is the number of <a href=\"/wiki/Decoy#Digital_decoys\" title=\"Decoy\">decoys</a> produced for that workunit multiplied by the average claimed credit for the decoys submitted by all computer hosts for that workunit. This custom system was designed to address significant differences between credit granted to users with the standard BOINC client and an optimized BOINC client, and credit differences between users running Rosetta@home on <a href=\"/wiki/Windows\" class=\"mw-redirect\" title=\"Windows\">Windows</a> and <a href=\"/wiki/Linux\" title=\"Linux\">Linux</a> operating systems.<sup id=\"cite_ref-76\" class=\"reference\"><a href=\"#cite_note-76\">[76]</a></sup> The amount of credit granted per second of CPU work is lower for Rosetta@home than most other BOINC projects.<sup id=\"cite_ref-pcp_77-0\" class=\"reference\"><a href=\"#cite_note-pcp-77\">[77]</a></sup> Despite this disadvantage to BOINC users competing for rank, Rosetta@home is fifth out of over 40 BOINC projects in terms of total credit.<sup id=\"cite_ref-78\" class=\"reference\"><a href=\"#cite_note-78\">[78]</a></sup>\n</p><p>Rosetta@home users who predict protein structures submitted for the <a href=\"/wiki/CASP\" title=\"CASP\">CASP</a> experiment are acknowledged in scientific publications regarding their results.<sup id=\"cite_ref-79\" class=\"reference\"><a href=\"#cite_note-79\">[79]</a></sup> Users who predict the lowest energy structure for a given workunit are featured on the Rosetta@home <a href=\"/wiki/Homepage\" class=\"mw-redirect\" title=\"Homepage\">homepage</a> as 'Predictor of the Day', along with any team of which they are a member.<sup id=\"cite_ref-80\" class=\"reference\"><a href=\"#cite_note-80\">[80]</a></sup> A 'User of the Day' is chosen at random each day to be on the homepage as well from users who have made a Rosetta@home profile.<sup id=\"cite_ref-81\" class=\"reference\"><a href=\"#cite_note-81\">[81]</a></sup>\n</p>\n<h2><span class=\"mw-headline\" id=\"References\">References</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=19\" title=\"Edit section: References\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<style data-mw-deduplicate=\"TemplateStyles:r1217336898\">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class=\"reflist reflist-columns references-column-width reflist-columns-2\">\n<ol class=\"references\">\n<li id=\"cite_note-1\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-1\">^</a></b></span> <span class=\"reference-text\"><style data-mw-deduplicate=\"TemplateStyles:r1215172403\">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:\"\\\"\"\"\\\"\"\"'\"\"'\"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url(\"//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg\")right 0.1em center/9px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a{background-size:contain}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url(\"//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg\")right 0.1em center/9px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a{background-size:contain}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url(\"//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg\")right 0.1em center/9px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a{background-size:contain}.mw-parser-output .cs1-ws-icon a{background:url(\"//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg\")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:#d33}.mw-parser-output .cs1-visible-error{color:#d33}.mw-parser-output .cs1-maint{display:none;color:#2C882D;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911F}html.skin-theme-clientpref-night .mw-parser-output .cs1-visible-error,html.skin-theme-clientpref-night .mw-parser-output .cs1-hidden-error{color:#f8a397}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-visible-error,html.skin-theme-clientpref-os .mw-parser-output .cs1-hidden-error{color:#f8a397}html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911F}}</style><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://depts.washington.edu/ventures/UW_Technology/Express_Licenses/rosetta.php\">\"Portfolio Highlight: Rosetta++ Software Suite\"</a>. UW TechTransfer \u2013 Digital Ventures.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Portfolio+Highlight%3A+Rosetta%2B%2B+Software+Suite&rft.pub=UW+TechTransfer+%E2%80%93+Digital+Ventures&rft_id=http%3A%2F%2Fdepts.washington.edu%2Fventures%2FUW_Technology%2FExpress_Licenses%2Frosetta.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-BOINCstats_RosettaOverview-2\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-BOINCstats_RosettaOverview_2-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-BOINCstats_RosettaOverview_2-1\"><sup><i><b>b</b></i></sup></a> <a href=\"#cite_ref-BOINCstats_RosettaOverview_2-2\"><sup><i><b>c</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFde_Zutter_W\" class=\"citation web cs1\">de Zutter W. <a rel=\"nofollow\" class=\"external text\" href=\"http://boincstats.com/stats/project_graph.php?pr=rosetta\">\"Rosetta@home: Credit overview\"</a>. boincstats.com.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Rosetta%40home%3A+Credit+overview&rft.pub=boincstats.com&rft.au=de+Zutter+W&rft_id=http%3A%2F%2Fboincstats.com%2Fstats%2Fproject_graph.php%3Fpr%3Drosetta&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-3\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-3\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_about.php\">\"What is Rosetta@home?\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=What+is+Rosetta%40home%3F&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_about.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-CAPRI3-4\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-CAPRI3_4-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-CAPRI3_4-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFLensink_MF,_M\u00e9ndez_R,_Wodak_SJ2007\" class=\"citation journal cs1\">Lensink MF, M\u00e9ndez R, Wodak SJ (2007). \"Docking and scoring protein complexes: CAPRI 3rd Edition\". <i>Proteins</i>. <b>69</b> (4): 704\u201318. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21804\">10.1002/prot.21804</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17918726\">17918726</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Docking+and+scoring+protein+complexes%3A+CAPRI+3rd+Edition&rft.volume=69&rft.issue=4&rft.pages=704-18&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21804&rft_id=info%3Apmid%2F17918726&rft.au=Lensink+MF%2C+M%C3%A9ndez+R%2C+Wodak+SJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-BOINCClient-5\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-BOINCClient_5-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-BOINCClient_5-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.berkeley.edu/download_all.php\">\"Download BOINC client software\"</a>. <i>BOINC</i>. University of California. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=BOINC&rft.atitle=Download+BOINC+client+software&rft.date=2008&rft_id=http%3A%2F%2Fboinc.berkeley.edu%2Fdownload_all.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-6\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-6\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_requirements.php\">\"Rosetta@home: Recommended System Requirements\"</a>. <i>Rosetta@home</i>. University of Washington. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+Recommended+System+Requirements&rft.date=2008&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_requirements.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-oldNews-7\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-oldNews_7-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-oldNews_7-1\"><sup><i><b>b</b></i></sup></a> <a href=\"#cite_ref-oldNews_7-2\"><sup><i><b>c</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/old_news.php\">\"Rosetta@home: News archive\"</a>. <i>Rosetta@home</i>. University of Washington. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+News+archive&rft.date=2008&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fold_news.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-8\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-8\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=669&nowrap=true#10910\">\"Rosetta@home: FAQ (work in progress) (message 10910)\"</a>. <i>Rosetta@home forums</i>. University of Washington. 2006.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+FAQ+%28work+in+progress%29+%28message+10910%29&rft.date=2006&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D669%26nowrap%3Dtrue%2310910&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-9\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-9\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFKim_DE2005\" class=\"citation web cs1\">Kim DE (2005). <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=391&nowrap=true#3155\">\"Rosetta@home: Random Seed (message 3155)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+Random+Seed+%28message+3155%29&rft.date=2005&rft.au=Kim+DE&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D391%26nowrap%3Dtrue%233155&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-10\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-10\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_graphics.php\">\"Rosetta@home: Quick guide to Rosetta and its graphics\"</a>. <i>Rosetta@home</i>. University of Washington. 2007.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+Quick+guide+to+Rosetta+and+its+graphics&rft.date=2007&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_graphics.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-11\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-11\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFKim_DE2008\" class=\"citation web cs1\">Kim DE (2008). <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=3934&nowrap=true#51199\">\"Rosetta@home: Problems with minirosetta version 1.+ (Message 51199)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+Problems+with+minirosetta+version+1.%2B+%28Message+51199%29&rft.date=2008&rft.au=Kim+DE&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D3934%26nowrap%3Dtrue%2351199&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-rosettaCommons-12\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-rosettaCommons_12-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-rosettaCommons_12-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.rosettacommons.org/main.html\">\"Rosetta Commons\"</a>. RosettaCommons.org. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Rosetta+Commons&rft.pub=RosettaCommons.org&rft.date=2008&rft_id=http%3A%2F%2Fwww.rosettacommons.org%2Fmain.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-13\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-13\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBourne_PE,_Helge_W2003\" class=\"citation book cs1\">Bourne PE, Helge W, ed. (2003). <i>Structural Bioinformatics</i>. Hoboken, NJ: Wiley-Liss. <a href=\"/wiki/ISBN_(identifier)\" class=\"mw-redirect\" title=\"ISBN (identifier)\">ISBN</a> <a href=\"/wiki/Special:BookSources/978-0471201991\" title=\"Special:BookSources/978-0471201991\"><bdi>978-0471201991</bdi></a>. <a href=\"/wiki/OCLC_(identifier)\" class=\"mw-redirect\" title=\"OCLC (identifier)\">OCLC</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://www.worldcat.org/oclc/50199108\">50199108</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Structural+Bioinformatics&rft.place=Hoboken%2C+NJ&rft.pub=Wiley-Liss&rft.date=2003&rft_id=info%3Aoclcnum%2F50199108&rft.isbn=978-0471201991&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span></span>\n</li>\n<li id=\"cite_note-14\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-14\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.pdb.org/pdb/statistics/contentGrowthChart.do?content=molType-protein&seqid=100\">\"Yearly Growth of Protein Structures\"</a>. RCSB Protein Data Bank. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Yearly+Growth+of+Protein+Structures&rft.pub=RCSB+Protein+Data+Bank&rft.date=2008&rft_id=http%3A%2F%2Fwww.pdb.org%2Fpdb%2Fstatistics%2FcontentGrowthChart.do%3Fcontent%3DmolType-protein%26seqid%3D100&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-15\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-15\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D2008\" class=\"citation web cs1\">Baker D (2008). <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#55893\">\"Rosetta@home: David Baker's Rosetta@home journal (message 55893)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+David+Baker%27s+Rosetta%40home+journal+%28message+55893%29&rft.date=2008&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D1177%26nowrap%3Dtrue%2355893&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-R@H_ResearchOverview-16\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-R@H_ResearchOverview_16-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-R@H_ResearchOverview_16-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_research.php\">\"Rosetta@home: Research Overview\"</a>. <i>Rosetta@home</i>. University of Washington. 2007.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+Research+Overview&rft.date=2007&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_research.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-17\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-17\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFKopp_J,_Bordoli_L,_Battey_JN,_Kiefer_F,_Schwede_T2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Kopp J, Bordoli L, Battey JN, Kiefer F, Schwede T (2007). \"Assessment of CASP7 predictions for template-based modeling targets\". <i>Proteins</i>. 69 Suppl 8: 38\u201356. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21753\">10.1002/prot.21753</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894352\">17894352</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Assessment+of+CASP7+predictions+for+template-based+modeling+targets&rft.volume=69+Suppl+8&rft.pages=38-56&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21753&rft_id=info%3Apmid%2F17894352&rft.au=Kopp+J%2C+Bordoli+L%2C+Battey+JN%2C+Kiefer+F%2C+Schwede+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-18\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-18\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFRead_RJ,_Chavali_G2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Read RJ, Chavali G (2007). \"Assessment of CASP7 predictions in the high accuracy template-based modeling category\". <i>Proteins</i>. 69 Suppl 8: 27\u201337. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21662\">10.1002/prot.21662</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894351\">17894351</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Assessment+of+CASP7+predictions+in+the+high+accuracy+template-based+modeling+category&rft.volume=69+Suppl+8&rft.pages=27-37&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21662&rft_id=info%3Apmid%2F17894351&rft.au=Read+RJ%2C+Chavali+G&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span></span>\n</li>\n<li id=\"cite_note-CASP7Assessment-19\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-CASP7Assessment_19-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-CASP7Assessment_19-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFJauch_R,_Yeo_HC,_Kolatkar_PR,_Clarke_ND2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Jauch R, Yeo HC, Kolatkar PR, Clarke ND (2007). \"Assessment of CASP7 structure predictions for template free targets\". <i>Proteins</i>. 69 Suppl 8: 57\u201367. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21771\">10.1002/prot.21771</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894330\">17894330</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Assessment+of+CASP7+structure+predictions+for+template+free+targets&rft.volume=69+Suppl+8&rft.pages=57-67&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21771&rft_id=info%3Apmid%2F17894330&rft.au=Jauch+R%2C+Yeo+HC%2C+Kolatkar+PR%2C+Clarke+ND&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-CASP7_baker-20\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-CASP7_baker_20-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-CASP7_baker_20-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFDas_R,_Qian_B,_Raman_S2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Das R, Qian B, Raman S; et al. (2007). \"Structure prediction for CASP7 targets using extensive all-atom refinement with Rosetta@home\". <i>Proteins</i>. 69 Suppl 8: 118\u201328. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21636\">10.1002/prot.21636</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894356\">17894356</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Structure+prediction+for+CASP7+targets+using+extensive+all-atom+refinement+with+Rosetta%40home&rft.volume=69+Suppl+8&rft.pages=118-28&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21636&rft_id=info%3Apmid%2F17894356&rft.au=Das+R%2C+Qian+B%2C+Raman+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-CAPRI3_1-21\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-CAPRI3_1_21-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-CAPRI3_1_21-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFWang_C,_Schueler-Furman_O,_Andre_I2007\" class=\"citation journal cs1\">Wang C, Schueler-Furman O, Andre I; et al. (2007). \"RosettaDock in CAPRI rounds 6-12\". <i>Proteins</i>. <b>69</b> (4): 758\u201363. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21684\">10.1002/prot.21684</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17671979\">17671979</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=RosettaDock+in+CAPRI+rounds+6-12&rft.volume=69&rft.issue=4&rft.pages=758-63&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21684&rft_id=info%3Apmid%2F17671979&rft.au=Wang+C%2C+Schueler-Furman+O%2C+Andre+I&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-RetroAldol-22\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-RetroAldol_22-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-RetroAldol_22-1\"><sup><i><b>b</b></i></sup></a> <a href=\"#cite_ref-RetroAldol_22-2\"><sup><i><b>c</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFJiang_L,_Althoff_EA,_Clemente_FR2008\" class=\"citation journal cs1\">Jiang L, Althoff EA, Clemente FR; et al. (2008). \"De novo computational design of retro-aldol enzymes\". <i>Science (New York, N.Y.)</i>. <b>319</b> (5868): 1387\u201391. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1126%2Fscience.1152692\">10.1126/science.1152692</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/18323453\">18323453</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+%28New+York%2C+N.Y.%29&rft.atitle=De+novo+computational+design+of+retro-aldol+enzymes&rft.volume=319&rft.issue=5868&rft.pages=1387-91&rft.date=2008&rft_id=info%3Adoi%2F10.1126%2Fscience.1152692&rft_id=info%3Apmid%2F18323453&rft.au=Jiang+L%2C+Althoff+EA%2C+Clemente+FR&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-23\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-23\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFHayden_EC2008\" class=\"citation journal cs1\">Hayden EC (February 13, 2008). <a rel=\"nofollow\" class=\"external text\" href=\"http://www.nature.com/news/2008/080213/full/news.2008.569.html\">\"Protein prize up for grabs after retraction\"</a>. <i>Nature</i>. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1038%2Fnews.2008.569\">10.1038/news.2008.569</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Protein+prize+up+for+grabs+after+retraction&rft.date=2008-02-13&rft_id=info%3Adoi%2F10.1038%2Fnews.2008.569&rft.au=Hayden+EC&rft_id=http%3A%2F%2Fwww.nature.com%2Fnews%2F2008%2F080213%2Ffull%2Fnews.2008.569.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-medicalRelevance-24\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-medicalRelevance_24-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-medicalRelevance_24-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_medical_relevance.php\">\"Disease Related Research\"</a>. <i>Rosetta@home</i>. University of Washington. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Disease+Related+Research&rft.date=2008&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_medical_relevance.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-25\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-25\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D2008\" class=\"citation web cs1\">Baker D (2008). <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177\">\"Rosetta@home: David Baker's Rosetta@home journal\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+David+Baker%27s+Rosetta%40home+journal&rft.date=2008&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D1177&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-26\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-26\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFKuhlman_B,_Baker_D2000\" class=\"citation journal cs1\">Kuhlman B, Baker D (2000). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27033\">\"Native protein sequences are close to optimal for their structures\"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. <b>97</b> (19): 10383\u20138. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1073%2Fpnas.97.19.10383\">10.1073/pnas.97.19.10383</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27033\">27033</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/10984534\">10984534</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Native+protein+sequences+are+close+to+optimal+for+their+structures&rft.volume=97&rft.issue=19&rft.pages=10383-8&rft.date=2000&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC27033%23id-name%3DPMC&rft_id=info%3Apmid%2F10984534&rft_id=info%3Adoi%2F10.1073%2Fpnas.97.19.10383&rft.au=Kuhlman+B%2C+Baker+D&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC27033&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-27\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-27\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFThompson_MJ,_Sievers_SA,_Karanicolas_J,_Ivanova_MI,_Baker_D,_Eisenberg_D2006\" class=\"citation journal cs1\">Thompson MJ, Sievers SA, Karanicolas J, Ivanova MI, Baker D, Eisenberg D (2006). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449648\">\"The 3D profile method for identifying fibril-forming segments of proteins\"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. <b>103</b> (11): 4074\u20138. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1073%2Fpnas.0511295103\">10.1073/pnas.0511295103</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449648\">1449648</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16537487\">16537487</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=The+3D+profile+method+for+identifying+fibril-forming+segments+of+proteins&rft.volume=103&rft.issue=11&rft.pages=4074-8&rft.date=2006&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1449648%23id-name%3DPMC&rft_id=info%3Apmid%2F16537487&rft_id=info%3Adoi%2F10.1073%2Fpnas.0511295103&rft.au=Thompson+MJ%2C+Sievers+SA%2C+Karanicolas+J%2C+Ivanova+MI%2C+Baker+D%2C+Eisenberg+D&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1449648&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-28\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-28\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBradley_P\" class=\"citation web cs1\">Bradley P. <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=2583&sort=6\">\"Rosetta@home forum: Amyloid fibril structure prediction\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home+forum%3A+Amyloid+fibril+structure+prediction&rft.au=Bradley+P&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D2583%26sort%3D6&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-29\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-29\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D\" class=\"citation web cs1\">Baker D. <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=4263&nowrap=true#54681\">\"Rosetta@home forum: Publications on R@H's Alzheimer's work? (message 54681)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home+forum%3A+Publications+on+R%40H%27s+Alzheimer%27s+work%3F+%28message+54681%29&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D4263%26nowrap%3Dtrue%2354681&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-30\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-30\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFWang_C,_Schueler-Furman_O,_Baker_D2005\" class=\"citation journal cs1\">Wang C, Schueler-Furman O, Baker D (2005). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253276\">\"Improved side-chain modeling for protein-protein docking\"</a>. <i>Protein science : a publication of the Protein Society</i>. <b>14</b> (5): 1328\u201339. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1110%2Fps.041222905\">10.1110/ps.041222905</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2253276\">2253276</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/15802647\">15802647</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Protein+science+%3A+a+publication+of+the+Protein+Society&rft.atitle=Improved+side-chain+modeling+for+protein-protein+docking&rft.volume=14&rft.issue=5&rft.pages=1328-39&rft.date=2005&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2253276%23id-name%3DPMC&rft_id=info%3Apmid%2F15802647&rft_id=info%3Adoi%2F10.1110%2Fps.041222905&rft.au=Wang+C%2C+Schueler-Furman+O%2C+Baker+D&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2253276&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-31\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-31\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFGray_JJ,_Moughon_S,_Wang_C2003\" class=\"citation journal cs1\">Gray JJ, Moughon S, Wang C; et al. (2003). \"Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations\". <i>Journal of molecular biology</i>. <b>331</b> (1): 281\u201399. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/12875852\">12875852</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+molecular+biology&rft.atitle=Protein-protein+docking+with+simultaneous+optimization+of+rigid-body+displacement+and+side-chain+conformations&rft.volume=331&rft.issue=1&rft.pages=281-99&rft.date=2003&rft_id=info%3Apmid%2F12875852&rft.au=Gray+JJ%2C+Moughon+S%2C+Wang+C&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-Schueler-Furman-32\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-Schueler-Furman_32-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-Schueler-Furman_32-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFSchueler-Furman_O,_Wang_C,_Baker_D2005\" class=\"citation journal cs1\">Schueler-Furman O, Wang C, Baker D (2005). \"Progress in protein-protein docking: atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side-chain flexibility\". <i>Proteins</i>. <b>60</b> (2): 187\u201394. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.20556\">10.1002/prot.20556</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/15981249\">15981249</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Progress+in+protein-protein+docking%3A+atomic+resolution+predictions+in+the+CAPRI+experiment+using+RosettaDock+with+an+improved+treatment+of+side-chain+flexibility&rft.volume=60&rft.issue=2&rft.pages=187-94&rft.date=2005&rft_id=info%3Adoi%2F10.1002%2Fprot.20556&rft_id=info%3Apmid%2F15981249&rft.au=Schueler-Furman+O%2C+Wang+C%2C+Baker+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-33\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-33\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFLacy_DB,_Lin_HC,_Melnyk_RA2005\" class=\"citation journal cs1\">Lacy DB, Lin HC, Melnyk RA; et al. (2005). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283467\">\"A model of anthrax toxin lethal factor bound to protective antigen\"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. <b>102</b> (45): 16409\u201314. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1073%2Fpnas.0508259102\">10.1073/pnas.0508259102</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283467\">1283467</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16251269\">16251269</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=A+model+of+anthrax+toxin+lethal+factor+bound+to+protective+antigen&rft.volume=102&rft.issue=45&rft.pages=16409-14&rft.date=2005&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1283467%23id-name%3DPMC&rft_id=info%3Apmid%2F16251269&rft_id=info%3Adoi%2F10.1073%2Fpnas.0508259102&rft.au=Lacy+DB%2C+Lin+HC%2C+Melnyk+RA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1283467&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-34\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-34\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFAlbrecht_MT,_Li_H,_Williamson_ED2007\" class=\"citation journal cs1\">Albrecht MT, Li H, Williamson ED; et al. (2007). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168292\">\"Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax\"</a>. <i>Infection and immunity</i>. <b>75</b> (11): 5425\u201333. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1128%2FIAI.00261-07\">10.1128/IAI.00261-07</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168292\">2168292</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17646360\">17646360</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Infection+and+immunity&rft.atitle=Human+monoclonal+antibodies+against+anthrax+lethal+factor+and+protective+antigen+act+independently+to+protect+against+Bacillus+anthracis+infection+and+enhance+endogenous+immunity+to+anthrax&rft.volume=75&rft.issue=11&rft.pages=5425-33&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2168292%23id-name%3DPMC&rft_id=info%3Apmid%2F17646360&rft_id=info%3Adoi%2F10.1128%2FIAI.00261-07&rft.au=Albrecht+MT%2C+Li+H%2C+Williamson+ED&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2168292&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-35\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-35\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFSprague_ER,_Wang_C,_Baker_D,_Bjorkman_PJ2006\" class=\"citation journal cs1\">Sprague ER, Wang C, Baker D, Bjorkman PJ (2006). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450327\">\"Crystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridging\"</a>. <i>PLoS biology</i>. <b>4</b> (6): e148. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1371%2Fjournal.pbio.0040148\">10.1371/journal.pbio.0040148</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450327\">1450327</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16646632\">16646632</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLoS+biology&rft.atitle=Crystal+structure+of+the+HSV-1+Fc+receptor+bound+to+Fc+reveals+a+mechanism+for+antibody+bipolar+bridging&rft.volume=4&rft.issue=6&rft.pages=e148&rft.date=2006&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1450327%23id-name%3DPMC&rft_id=info%3Apmid%2F16646632&rft_id=info%3Adoi%2F10.1371%2Fjournal.pbio.0040148&rft.au=Sprague+ER%2C+Wang+C%2C+Baker+D%2C+Bjorkman+PJ&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1450327&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>) CS1 maint: unflagged free DOI (<a href=\"/wiki/Category:CS1_maint:_unflagged_free_DOI\" title=\"Category:CS1 maint: unflagged free DOI\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-36\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-36\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFPaulson,_Tom2006\" class=\"citation news cs1\">Paulson, Tom (July 19, 2006). <a rel=\"nofollow\" class=\"external text\" href=\"http://seattlepi.nwsource.com/local/278100_aidsvaccine19ww.html\">\"Gates Foundation awards $287 million for HIV vaccine research\"</a>. <i>Seattle Post-Intelligencer</i>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Seattle+Post-Intelligencer&rft.atitle=Gates+Foundation+awards+%24287+million+for+HIV+vaccine+research&rft.date=2006-07-19&rft.au=Paulson%2C+Tom&rft_id=http%3A%2F%2Fseattlepi.nwsource.com%2Flocal%2F278100_aidsvaccine19ww.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_news\" title=\"Template:Cite news\">cite news</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-37\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-37\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFLiu_Y2007\" class=\"citation web cs1\">Liu Y; et al. (2007). <a rel=\"nofollow\" class=\"external text\" href=\"http://www.hivvaccineenterprise.org/_dwn/Oral_Sessions.pdf\">\"Development of IgG1 b12 scaffolds and HIV-1 env-based outer domain immunogens capable of eliciting and detecting IgG1 b12-like antibodies\"</a> <span class=\"cs1-format\">(PDF)</span>. Global HIV Vaccine Enterprise.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Development+of+IgG1+b12+scaffolds+and+HIV-1+env-based+outer+domain+immunogens+capable+of+eliciting+and+detecting+IgG1+b12-like+antibodies&rft.pub=Global+HIV+Vaccine+Enterprise&rft.date=2007&rft.au=Liu+Y&rft_id=http%3A%2F%2Fwww.hivvaccineenterprise.org%2F_dwn%2FOral_Sessions.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-38\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-38\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D\" class=\"citation web cs1\">Baker D. <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=2431&nowrap=true#40756\">\"David Baker's Rosetta@home journal archives (message 40756)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=David+Baker%27s+Rosetta%40home+journal+archives+%28message+40756%29&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D2431%26nowrap%3Dtrue%2340756&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-39\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-39\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.gcgh.org/ControlInsect/Challenges/GeneticStrategy/Pages/EndonucleaseGenes.aspx\">\"Homing Endonuclease Genes: New Tools for Mosquito Population Engineering and Control\"</a>. Grand Challenges in Global Health.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Homing+Endonuclease+Genes%3A+New+Tools+for+Mosquito+Population+Engineering+and+Control&rft.pub=Grand+Challenges+in+Global+Health&rft_id=http%3A%2F%2Fwww.gcgh.org%2FControlInsect%2FChallenges%2FGeneticStrategy%2FPages%2FEndonucleaseGenes.aspx&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-40\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-40\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFWindbichler_N,_Papathanos_PA,_Catteruccia_F,_Ranson_H,_Burt_A,_Crisanti_A2007\" class=\"citation journal cs1\">Windbichler N, Papathanos PA, Catteruccia F, Ranson H, Burt A, Crisanti A (2007). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034484\">\"Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos\"</a>. <i>Nucleic acids research</i>. <b>35</b> (17): 5922\u201333. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1093%2Fnar%2Fgkm632\">10.1093/nar/gkm632</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034484\">2034484</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17726053\">17726053</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+acids+research&rft.atitle=Homing+endonuclease+mediated+gene+targeting+in+Anopheles+gambiae+cells+and+embryos&rft.volume=35&rft.issue=17&rft.pages=5922-33&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2034484%23id-name%3DPMC&rft_id=info%3Apmid%2F17726053&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkm632&rft.au=Windbichler+N%2C+Papathanos+PA%2C+Catteruccia+F%2C+Ranson+H%2C+Burt+A%2C+Crisanti+A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2034484&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-41\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-41\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFAshworth_J,_Havranek_JJ,_Duarte_CM2006\" class=\"citation journal cs1\">Ashworth J, Havranek JJ, Duarte CM; et al. (2006). \"Computational redesign of endonuclease DNA binding and cleavage specificity\". <i>Nature</i>. <b>441</b> (7093): 656\u20139. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1038%2Fnature04818\">10.1038/nature04818</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16738662\">16738662</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Computational+redesign+of+endonuclease+DNA+binding+and+cleavage+specificity&rft.volume=441&rft.issue=7093&rft.pages=656-9&rft.date=2006&rft_id=info%3Adoi%2F10.1038%2Fnature04818&rft_id=info%3Apmid%2F16738662&rft.au=Ashworth+J%2C+Havranek+JJ%2C+Duarte+CM&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-42\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-42\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFSimons_KT,_Bonneau_R,_Ruczinski_I,_Baker_D1999\" class=\"citation journal cs1 cs1-prop-long-vol\">Simons KT, Bonneau R, Ruczinski I, Baker D (1999). \"Ab initio protein structure prediction of CASP III targets using ROSETTA\". <i>Proteins</i>. Suppl 3: 171\u20136. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/10526365\">10526365</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Ab+initio+protein+structure+prediction+of+CASP+III+targets+using+ROSETTA&rft.volume=Suppl+3&rft.pages=171-6&rft.date=1999&rft_id=info%3Apmid%2F10526365&rft.au=Simons+KT%2C+Bonneau+R%2C+Ruczinski+I%2C+Baker+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-43\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-43\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFNauli_S,_Kuhlman_B,_Baker_D2001\" class=\"citation journal cs1\">Nauli S, Kuhlman B, Baker D (2001). \"Computer-based redesign of a protein folding pathway\". <i>Nature structural biology</i>. <b>8</b> (7): 602\u20135. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1038%2F89638\">10.1038/89638</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/11427890\">11427890</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature+structural+biology&rft.atitle=Computer-based+redesign+of+a+protein+folding+pathway&rft.volume=8&rft.issue=7&rft.pages=602-5&rft.date=2001&rft_id=info%3Adoi%2F10.1038%2F89638&rft_id=info%3Apmid%2F11427890&rft.au=Nauli+S%2C+Kuhlman+B%2C+Baker+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-44\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-44\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFKuhlman_B,_Dantas_G,_Ireton_GC,_Varani_G,_Stoddard_BL,_Baker_D2003\" class=\"citation journal cs1\">Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D (2003). \"Design of a novel globular protein fold with atomic-level accuracy\". <i>Science (New York, N.Y.)</i>. <b>302</b> (5649): 1364\u20138. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1126%2Fscience.1089427\">10.1126/science.1089427</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/14631033\">14631033</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+%28New+York%2C+N.Y.%29&rft.atitle=Design+of+a+novel+globular+protein+fold+with+atomic-level+accuracy&rft.volume=302&rft.issue=5649&rft.pages=1364-8&rft.date=2003&rft_id=info%3Adoi%2F10.1126%2Fscience.1089427&rft_id=info%3Apmid%2F14631033&rft.au=Kuhlman+B%2C+Dantas+G%2C+Ireton+GC%2C+Varani+G%2C+Stoddard+BL%2C+Baker+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-45\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-45\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFJones_DT2003\" class=\"citation journal cs1\">Jones DT (2003). \"Structural biology. Learning to speak the language of proteins\". <i>Science (New York, N.Y.)</i>. <b>302</b> (5649): 1347\u20138. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1126%2Fscience.1092492\">10.1126/science.1092492</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/14631028\">14631028</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+%28New+York%2C+N.Y.%29&rft.atitle=Structural+biology.+Learning+to+speak+the+language+of+proteins&rft.volume=302&rft.issue=5649&rft.pages=1347-8&rft.date=2003&rft_id=info%3Adoi%2F10.1126%2Fscience.1092492&rft_id=info%3Apmid%2F14631028&rft.au=Jones+DT&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-46\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-46\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFvon_Grotthuss_M,_Wyrwicz_LS,_Pas_J,_Rychlewski_L2004\" class=\"citation journal cs1\">von Grotthuss M, Wyrwicz LS, Pas J, Rychlewski L (2004). \"Predicting protein structures accurately\". <i>Science (New York, N.Y.)</i>. <b>304</b> (5677): 1597\u20139, author reply 1597\u20139. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1126%2Fscience.304.5677.1597b\">10.1126/science.304.5677.1597b</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/15192202\">15192202</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Science+%28New+York%2C+N.Y.%29&rft.atitle=Predicting+protein+structures+accurately&rft.volume=304&rft.issue=5677&rft.pages=1597-9%2C+author+reply+1597-9&rft.date=2004&rft_id=info%3Adoi%2F10.1126%2Fscience.304.5677.1597b&rft_id=info%3Apmid%2F15192202&rft.au=von+Grotthuss+M%2C+Wyrwicz+LS%2C+Pas+J%2C+Rychlewski+L&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-47\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-47\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.sciencemag.org/cgi/external_ref?access_num=sci%3B302%2F5649%2F1364&link_type=ISI_Citing\">\"Articles citing: Kuhlman et al (2003) 'Design of a novel globular protein fold with atomic-level accuracy'<span class=\"cs1-kern-right\"></span>\"</a>. ISI Web of Science.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Articles+citing%3A+Kuhlman+et+al+%282003%29+%27Design+of+a+novel+globular+protein+fold+with+atomic-level+accuracy%27&rft.pub=ISI+Web+of+Science&rft_id=http%3A%2F%2Fwww.sciencemag.org%2Fcgi%2Fexternal_ref%3Faccess_num%3Dsci%253B302%252F5649%252F1364%26link_type%3DISI_Citing&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-48\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-48\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb70_1.html\">\"October 2005 molecule of the month: Designer proteins\"</a>. RCSB Protein Data Bank.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=October+2005+molecule+of+the+month%3A+Designer+proteins&rft.pub=RCSB+Protein+Data+Bank&rft_id=http%3A%2F%2Fwww.pdb.org%2Fpdb%2Fstatic.do%3Fp%3Deducation_discussion%2Fmolecule_of_the_month%2Fpdb70_1.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-49\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-49\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://www.unc.edu/kuhlmanpg/index.htm\">\"Kuhlman laboratory homepage\"</a>. <i>Kuhlman Laboratory</i>. University of North Carolina.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Kuhlman+Laboratory&rft.atitle=Kuhlman+laboratory+homepage&rft_id=http%3A%2F%2Fwww.unc.edu%2Fkuhlmanpg%2Findex.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-50\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-50\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://rosettadesign.med.unc.edu/\">\"RosettaDesign web server\"</a>. <i>Kuhlman Laboratory</i>. University of North Carolina.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Kuhlman+Laboratory&rft.atitle=RosettaDesign+web+server&rft_id=http%3A%2F%2Frosettadesign.med.unc.edu%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-CAPRI_1-51\"><span class=\"mw-cite-backlink\">^ <a href=\"#cite_ref-CAPRI_1_51-0\"><sup><i><b>a</b></i></sup></a> <a href=\"#cite_ref-CAPRI_1_51-1\"><sup><i><b>b</b></i></sup></a></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFGray_JJ,_Moughon_SE,_Kortemme_T2003\" class=\"citation journal cs1\">Gray JJ, Moughon SE, Kortemme T; et al. (2003). \"Protein-protein docking predictions for the CAPRI experiment\". <i>Proteins</i>. <b>52</b> (1): 118\u201322. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.10384\">10.1002/prot.10384</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/12784377\">12784377</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Protein-protein+docking+predictions+for+the+CAPRI+experiment&rft.volume=52&rft.issue=1&rft.pages=118-22&rft.date=2003&rft_id=info%3Adoi%2F10.1002%2Fprot.10384&rft_id=info%3Apmid%2F12784377&rft.au=Gray+JJ%2C+Moughon+SE%2C+Kortemme+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-52\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-52\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFDaily_MD,_Masica_D,_Sivasubramanian_A,_Somarouthu_S,_Gray_JJ2005\" class=\"citation journal cs1\">Daily MD, Masica D, Sivasubramanian A, Somarouthu S, Gray JJ (2005). <a rel=\"nofollow\" class=\"external text\" href=\"http://www3.interscience.wiley.com/cgi-bin/fulltext/110548131/HTMLSTART\">\"CAPRI rounds 3-5 reveal promising successes and future challenges for RosettaDock\"</a>. <i>Proteins</i>. <b>60</b> (2): 181\u201386. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.20555\">10.1002/prot.20555</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/15981262\">15981262</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=CAPRI+rounds+3-5+reveal+promising+successes+and+future+challenges+for+RosettaDock&rft.volume=60&rft.issue=2&rft.pages=181-86&rft.date=2005&rft_id=info%3Adoi%2F10.1002%2Fprot.20555&rft_id=info%3Apmid%2F15981262&rft.au=Daily+MD%2C+Masica+D%2C+Sivasubramanian+A%2C+Somarouthu+S%2C+Gray+JJ&rft_id=http%3A%2F%2Fwww3.interscience.wiley.com%2Fcgi-bin%2Ffulltext%2F110548131%2FHTMLSTART&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-53\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-53\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFM\u00e9ndez_R,_Leplae_R,_Lensink_MF,_Wodak_SJ2005\" class=\"citation journal cs1\">M\u00e9ndez R, Leplae R, Lensink MF, Wodak SJ (2005). <a rel=\"nofollow\" class=\"external text\" href=\"http://www3.interscience.wiley.com/cgi-bin/fulltext/110548130/HTMLSTART\">\"Assessment of CAPRI predictions in rounds 3-5 shows progress in docking procedures\"</a>. <i>Proteins</i>. <b>60</b> (2): 150\u201369. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.20551\">10.1002/prot.20551</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/15981261\">15981261</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Assessment+of+CAPRI+predictions+in+rounds+3-5+shows+progress+in+docking+procedures&rft.volume=60&rft.issue=2&rft.pages=150-69&rft.date=2005&rft_id=info%3Adoi%2F10.1002%2Fprot.20551&rft_id=info%3Apmid%2F15981261&rft.au=M%C3%A9ndez+R%2C+Leplae+R%2C+Lensink+MF%2C+Wodak+SJ&rft_id=http%3A%2F%2Fwww3.interscience.wiley.com%2Fcgi-bin%2Ffulltext%2F110548130%2FHTMLSTART&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-54\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-54\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://rosettadock.graylab.jhu.edu/\">\"RosettaDock server\"</a>. <i>Gray laboratory</i>. Johns Hopkins University.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Gray+laboratory&rft.atitle=RosettaDock+server&rft_id=http%3A%2F%2Frosettadock.graylab.jhu.edu%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-55\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-55\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=2395\">\"Protein-protein docking at Rosetta@home\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Protein-protein+docking+at+Rosetta%40home&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D2395&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-56\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-56\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://robetta.bakerlab.org/\">\"Robetta web server\"</a>. <i>Baker laboratory</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Baker+laboratory&rft.atitle=Robetta+web+server&rft_id=http%3A%2F%2Frobetta.bakerlab.org%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-57\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-57\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFAloy_P,_Stark_A,_Hadley_C,_Russell_RB2003\" class=\"citation journal cs1 cs1-prop-long-vol\">Aloy P, Stark A, Hadley C, Russell RB (2003). \"Predictions without templates: new folds, secondary structure, and contacts in CASP5\". <i>Proteins</i>. 53 Suppl 6: 436\u201356. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.10546\">10.1002/prot.10546</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/14579333\">14579333</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Predictions+without+templates%3A+new+folds%2C+secondary+structure%2C+and+contacts+in+CASP5&rft.volume=53+Suppl+6&rft.pages=436-56&rft.date=2003&rft_id=info%3Adoi%2F10.1002%2Fprot.10546&rft_id=info%3Apmid%2F14579333&rft.au=Aloy+P%2C+Stark+A%2C+Hadley+C%2C+Russell+RB&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-58\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-58\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFTress_M,_Ezkurdia_I,_Gra\u00f1a_O,_L\u00f3pez_G,_Valencia_A2005\" class=\"citation journal cs1 cs1-prop-long-vol\">Tress M, Ezkurdia I, Gra\u00f1a O, L\u00f3pez G, Valencia A (2005). \"Assessment of predictions submitted for the CASP6 comparative modeling category\". <i>Proteins</i>. 61 Suppl 7: 27\u201345. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.20720\">10.1002/prot.20720</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16187345\">16187345</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Assessment+of+predictions+submitted+for+the+CASP6+comparative+modeling+category&rft.volume=61+Suppl+7&rft.pages=27-45&rft.date=2005&rft_id=info%3Adoi%2F10.1002%2Fprot.20720&rft_id=info%3Apmid%2F16187345&rft.au=Tress+M%2C+Ezkurdia+I%2C+Gra%C3%B1a+O%2C+L%C3%B3pez+G%2C+Valencia+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-59\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-59\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBattey_JN,_Kopp_J,_Bordoli_L,_Read_RJ,_Clarke_ND,_Schwede_T2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Battey JN, Kopp J, Bordoli L, Read RJ, Clarke ND, Schwede T (2007). \"Automated server predictions in CASP7\". <i>Proteins</i>. 69 Suppl 8: 68\u201382. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21761\">10.1002/prot.21761</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894354\">17894354</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Automated+server+predictions+in+CASP7&rft.volume=69+Suppl+8&rft.pages=68-82&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21761&rft_id=info%3Apmid%2F17894354&rft.au=Battey+JN%2C+Kopp+J%2C+Bordoli+L%2C+Read+RJ%2C+Clarke+ND%2C+Schwede+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-60\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-60\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFChivian_D,_Kim_DE,_Malmstr\u00f6m_L,_Schonbrun_J,_Rohl_CA,_Baker_D2005\" class=\"citation journal cs1 cs1-prop-long-vol\">Chivian D, Kim DE, Malmstr\u00f6m L, Schonbrun J, Rohl CA, Baker D (2005). \"Prediction of CASP6 structures using automated Robetta protocols\". <i>Proteins</i>. 61 Suppl 7: 157\u201366. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.20733\">10.1002/prot.20733</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/16187358\">16187358</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Prediction+of+CASP6+structures+using+automated+Robetta+protocols&rft.volume=61+Suppl+7&rft.pages=157-66&rft.date=2005&rft_id=info%3Adoi%2F10.1002%2Fprot.20733&rft_id=info%3Apmid%2F16187358&rft.au=Chivian+D%2C+Kim+DE%2C+Malmstr%C3%B6m+L%2C+Schonbrun+J%2C+Rohl+CA%2C+Baker+D&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span><span class=\"cs1-maint citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-61\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-61\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D\" class=\"citation web cs1\">Baker D. <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#52902\">\"David Baker's Rosetta@home journal, message 52902\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=David+Baker%27s+Rosetta%40home+journal%2C+message+52902&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D1177%26nowrap%3Dtrue%2352902&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-62\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-62\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBaker_D\" class=\"citation web cs1\">Baker D. <a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#52963\">\"David Baker's Rosetta@home journal (message 52963)\"</a>. <i>Rosetta@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=David+Baker%27s+Rosetta%40home+journal+%28message+52963%29&rft.au=Baker+D&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D1177%26nowrap%3Dtrue%2352963&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-63\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-63\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://fold.it/portal/node/444975\">\"Foldit forums: How many users does Foldit have? Etc. (message 2)\"</a>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Foldit+forums%3A+How+many+users+does+Foldit+have%3F+Etc.+%28message+2%29&rft.pub=University+of+Washington&rft_id=http%3A%2F%2Ffold.it%2Fportal%2Fnode%2F444975&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-64\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-64\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://fold.it/portal/info/faq\">\"Foldit: Frequently Asked Questions\"</a>. <i>fold.it</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=fold.it&rft.atitle=Foldit%3A+Frequently+Asked+Questions&rft_id=http%3A%2F%2Ffold.it%2Fportal%2Finfo%2Ffaq&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-65\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-65\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.berkeley.edu/wiki/Project_list\">\"Project list - BOINC\"</a>. University of California.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Project+list+-+BOINC&rft.pub=University+of+California&rft_id=http%3A%2F%2Fboinc.berkeley.edu%2Fwiki%2FProject_list&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-66\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-66\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://folding.stanford.edu/English/FAQ-Diseases\">\"Folding@home - FAQ-Diseases\"</a>. Stanford University. 2007.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Folding%40home+-+FAQ-Diseases&rft.pub=Stanford+University&rft.date=2007&rft_id=http%3A%2F%2Ffolding.stanford.edu%2FEnglish%2FFAQ-Diseases&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-67\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-67\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://folding.stanford.edu/Japanese/About\">\"Folding@home - About\"</a>. Stanford University. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Folding%40home+-+About&rft.pub=Stanford+University&rft.date=2008&rft_id=http%3A%2F%2Ffolding.stanford.edu%2FJapanese%2FAbout&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-68\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-68\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://fah-web.stanford.edu/cgi-bin/main.py?qtype=osstats\">\"Client statistics by OS\"</a>. Stanford University.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Client+statistics+by+OS&rft.pub=Stanford+University&rft_id=http%3A%2F%2Ffah-web.stanford.edu%2Fcgi-bin%2Fmain.py%3Fqtype%3Dosstats&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-69\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-69\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFMalmstr\u00f6m_L,_Riffle_M,_Strauss_CE2007\" class=\"citation journal cs1\">Malmstr\u00f6m L, Riffle M, Strauss CE; et al. (2007). <a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828141\">\"Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology\"</a>. <i>PLoS biology</i>. <b>5</b> (4): e76. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1371%2Fjournal.pbio.0050076\">10.1371/journal.pbio.0050076</a>. <a href=\"/wiki/PMC_(identifier)\" class=\"mw-redirect\" title=\"PMC (identifier)\">PMC</a> <span class=\"id-lock-free\" title=\"Freely accessible\"><a rel=\"nofollow\" class=\"external text\" href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828141\">1828141</a></span>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17373854\">17373854</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=PLoS+biology&rft.atitle=Superfamily+assignments+for+the+yeast+proteome+through+integration+of+structure+prediction+with+the+gene+ontology&rft.volume=5&rft.issue=4&rft.pages=e76&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1828141%23id-name%3DPMC&rft_id=info%3Apmid%2F17373854&rft_id=info%3Adoi%2F10.1371%2Fjournal.pbio.0050076&rft.au=Malmstr%C3%B6m+L%2C+Riffle+M%2C+Strauss+CE&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1828141&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|month=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>) CS1 maint: unflagged free DOI (<a href=\"/wiki/Category:CS1_maint:_unflagged_free_DOI\" title=\"Category:CS1 maint: unflagged free DOI\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-70\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-70\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBonneau_R2006\" class=\"citation web cs1\">Bonneau R (2006). <a rel=\"nofollow\" class=\"external text\" href=\"http://homepages.nyu.edu/~rb133/wcg/thread_7398.html\">\"World Community Grid Message Board Posts: HPF -> HPF2 transition\"</a>. Bonneau Lab, New York University.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=World+Community+Grid+Message+Board+Posts%3A+HPF+-%3E+HPF2+transition&rft.pub=Bonneau+Lab%2C+New+York+University&rft.date=2006&rft.au=Bonneau+R&rft_id=http%3A%2F%2Fhomepages.nyu.edu%2F~rb133%2Fwcg%2Fthread_7398.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-71\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-71\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://homepages.nyu.edu/~rb133/papers.html\">\"List of Richard Bonneau's publications\"</a>. Bonneau Lab, New York University.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=List+of+Richard+Bonneau%27s+publications&rft.pub=Bonneau+Lab%2C+New+York+University&rft_id=http%3A%2F%2Fhomepages.nyu.edu%2F~rb133%2Fpapers.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-72\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-72\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFBonneau_R\" class=\"citation web cs1\">Bonneau R. <a rel=\"nofollow\" class=\"external text\" href=\"http://homepages.nyu.edu/~rb133/wcg/rbonneau_posts.html\">\"World Community Grid Message Board Posts\"</a>. Bonneau Lab, New York University.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=World+Community+Grid+Message+Board+Posts&rft.pub=Bonneau+Lab%2C+New+York+University&rft.au=Bonneau+R&rft_id=http%3A%2F%2Fhomepages.nyu.edu%2F~rb133%2Fwcg%2Frbonneau_posts.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-73\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-73\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://predictor.chem.lsa.umich.edu/scientific_update_cp.php#dpath\">\"Predictor@home: Developing new application areas for P@H\"</a>. The Brooks Research Group.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Predictor%40home%3A+Developing+new+application+areas+for+P%40H&rft.pub=The+Brooks+Research+Group&rft_id=http%3A%2F%2Fpredictor.chem.lsa.umich.edu%2Fscientific_update_cp.php%23dpath&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-74\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-74\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFCarrillo-Tripp_M2007\" class=\"citation web cs1\">Carrillo-Tripp M (2007). <a rel=\"nofollow\" class=\"external text\" href=\"http://www.scripps.edu/~trippm/dtasser/\">\"dTASSER\"</a>. The Scripps Research Institute.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=dTASSER&rft.pub=The+Scripps+Research+Institute&rft.date=2007&rft.au=Carrillo-Tripp+M&rft_id=http%3A%2F%2Fwww.scripps.edu%2F~trippm%2Fdtasser%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-75\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-75\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://ralph.bakerlab.org/\">\"RALPH@home website\"</a>. <i>RALPH@home forums</i>. University of Washington.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=RALPH%40home+forums&rft.atitle=RALPH%40home+website&rft_id=http%3A%2F%2Fralph.bakerlab.org%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-76\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-76\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=2194\">\"Rosetta@home: The new credit system explained\"</a>. <i>Rosetta@home forums</i>. University of Washington. 2006.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home+forums&rft.atitle=Rosetta%40home%3A+The+new+credit+system+explained&rft.date=2006&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Fforum_thread.php%3Fid%3D2194&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-pcp-77\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-pcp_77-0\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boincstats.com/stats/project_cpcs.php\">\"BOINCstats: Project Credit Comparison\"</a>. boincstats.com. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=BOINCstats%3A+Project+Credit+Comparison&rft.pub=boincstats.com&rft.date=2008&rft_id=http%3A%2F%2Fboincstats.com%2Fstats%2Fproject_cpcs.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-78\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-78\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boincstats.com/charts/chart_uk_bo_project_pie3dcredits.gif\">\"Credit divided over projects\"</a>. boincstats.com.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Credit+divided+over+projects&rft.pub=boincstats.com&rft_id=http%3A%2F%2Fboincstats.com%2Fcharts%2Fchart_uk_bo_project_pie3dcredits.gif&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-79\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-79\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite id=\"CITEREFDas_R,_Qian_B,_Raman_S2007\" class=\"citation journal cs1 cs1-prop-long-vol\">Das R, Qian B, Raman S; et al. (2007). \"Structure prediction for CASP7 targets using extensive all-atom refinement with Rosetta@home\". <i>Proteins</i>. 69 Suppl 8: 118\u201328. <a href=\"/wiki/Doi_(identifier)\" class=\"mw-redirect\" title=\"Doi (identifier)\">doi</a>:<a rel=\"nofollow\" class=\"external text\" href=\"https://doi.org/10.1002%2Fprot.21636\">10.1002/prot.21636</a>. <a href=\"/wiki/PMID_(identifier)\" class=\"mw-redirect\" title=\"PMID (identifier)\">PMID</a> <a rel=\"nofollow\" class=\"external text\" href=\"https://pubmed.ncbi.nlm.nih.gov/17894356\">17894356</a>.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proteins&rft.atitle=Structure+prediction+for+CASP7+targets+using+extensive+all-atom+refinement+with+Rosetta%40home&rft.volume=69+Suppl+8&rft.pages=118-28&rft.date=2007&rft_id=info%3Adoi%2F10.1002%2Fprot.21636&rft_id=info%3Apmid%2F17894356&rft.au=Das+R%2C+Qian+B%2C+Raman+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_journal\" title=\"Template:Cite journal\">cite journal</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Explicit use of et al. in: <code class=\"cs1-code\">|author=</code> (<a href=\"/wiki/Help:CS1_errors#explicit_et_al\" title=\"Help:CS1 errors\">help</a>)</span><span class=\"cs1-maint citation-comment\">CS1 maint: multiple names: authors list (<a href=\"/wiki/Category:CS1_maint:_multiple_names:_authors_list\" title=\"Category:CS1 maint: multiple names: authors list\">link</a>)</span></span>\n</li>\n<li id=\"cite_note-80\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-80\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/rah_old_potd.php\">\"Rosetta@home: Predictor of the day archive\"</a>. <i>Rosetta@home</i>. University of Washington. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+Predictor+of+the+day+archive&rft.date=2008&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta%2Frah_old_potd.php&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n<li id=\"cite_note-81\"><span class=\"mw-cite-backlink\"><b><a href=\"#cite_ref-81\">^</a></b></span> <span class=\"reference-text\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1215172403\"><cite class=\"citation web cs1\"><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta\">\"Rosetta@home: Protein Folding, Design, and Docking\"</a>. <i>Rosetta@home</i>. University of Washington. 2008.</cite><span title=\"ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Rosetta%40home&rft.atitle=Rosetta%40home%3A+Protein+Folding%2C+Design%2C+and+Docking&rft.date=2008&rft_id=http%3A%2F%2Fboinc.bakerlab.org%2Frosetta&rfr_id=info%3Asid%2Fen.wikipedia.org%3ARosetta%40home\" class=\"Z3988\"></span> <span class=\"cs1-visible-error citation-comment\"><code class=\"cs1-code\">{{<a href=\"/wiki/Template:Cite_web\" title=\"Template:Cite web\">cite web</a>}}</code>: </span><span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessmonthday=</code> ignored (<a href=\"/wiki/Help:CS1_errors#parameter_ignored\" title=\"Help:CS1 errors\">help</a>)</span>; <span class=\"cs1-visible-error citation-comment\">Unknown parameter <code class=\"cs1-code\">|accessyear=</code> ignored (<code class=\"cs1-code\">|access-date=</code> suggested) (<a href=\"/wiki/Help:CS1_errors#parameter_ignored_suggest\" title=\"Help:CS1 errors\">help</a>)</span></span>\n</li>\n</ol></div>\n<h2><span class=\"mw-headline\" id=\"External_links\">External links</span><span class=\"mw-editsection\"><span class=\"mw-editsection-bracket\">[</span><a href=\"/w/index.php?title=Rosetta@home&action=edit&section=20\" title=\"Edit section: External links\"><span>edit</span></a><span class=\"mw-editsection-bracket\">]</span></span></h2>\n<ul><li><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/\">Rosetta@home</a> Project website</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://ralph.bakerlab.org/\">RALPH@home</a> Website for Rosetta@home alpha testing project</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&sort=5\">David Baker's Rosetta@home journal</a></li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://boincstats.com/stats/project_graph.php?pr=rosetta\">BOINCstats \u2013 Rosetta@home</a> Detailed contribution statistics</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"https://www.youtube.com/watch?v=GzATbET3g54\">Rosetta@home video on YouTube</a> Overview of Rosetta@home given by David Baker and lab members</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://boinc.berkeley.edu/\">BOINC</a> Main page for the BOINC platform. Includes platform overview, as well as a guide for installing BOINC and attaching to Rosetta@home</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://www.rosettacommons.org/\">Rosetta Commons</a> Academic collaborative for development of the Rosetta platform</li></ul>\n<p><b>Online Rosetta services</b>\n</p>\n<ul><li><a rel=\"nofollow\" class=\"external text\" href=\"http://robetta.bakerlab.org/\">Robetta</a> Protein structure prediction server</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://rosettadesign.med.unc.edu/\">RosettaDesign</a> Protein design server</li>\n<li><a rel=\"nofollow\" class=\"external text\" href=\"http://rosettadock.graylab.jhu.edu/\">RosettaDock</a> Protein-protein docking server</li></ul>\n<div class=\"navbox-styles\"><style data-mw-deduplicate=\"TemplateStyles:r1129693374\">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:\": \"}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:\" \u00b7 \";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:\" (\";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:\")\";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:\" \"counter(listitem)\"\\a0 \"}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:\" (\"counter(listitem)\"\\a0 \"}</style><style data-mw-deduplicate=\"TemplateStyles:r1061467846\">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output .navbox-list{line-height:1.5em;border-color:#fdfdfd}.mw-parser-output .navbox-list-with-group{text-align:left;border-left-width:2px;border-left-style:solid}.mw-parser-output tr+tr>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}</style></div><div role=\"navigation\" class=\"navbox\" aria-labelledby=\"Berkeley_Open_Infrastructure_for_Network_Computing_(BOINC)_projects\" style=\"padding:3px\"><table class=\"nowraplinks mw-collapsible autocollapse navbox-inner\" style=\"border-spacing:0;background:transparent;color:inherit\"><tbody><tr><th scope=\"col\" class=\"navbox-title\" colspan=\"2\"><link rel=\"mw-deduplicated-inline-style\" href=\"mw-data:TemplateStyles:r1129693374\"><style data-mw-deduplicate=\"TemplateStyles:r1063604349\">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:\"[ \"}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:\" ]\"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}</style><div class=\"navbar plainlinks hlist navbar-mini\"><ul><li class=\"nv-view\"><a href=\"/wiki/Template:BOINC_projects\" title=\"Template:BOINC projects\"><abbr title=\"View this template\" style=\";;background:none transparent;border:none;box-shadow:none;padding:0;\">v</abbr></a></li><li class=\"nv-talk\"><a href=\"/wiki/Template_talk:BOINC_projects\" title=\"Template talk:BOINC projects\"><abbr title=\"Discuss this template\" style=\";;background:none transparent;border:none;box-shadow:none;padding:0;\">t</abbr></a></li><li class=\"nv-edit\"><a href=\"/wiki/Special:EditPage/Template:BOINC_projects\" title=\"Special:EditPage/Template:BOINC projects\"><abbr title=\"Edit this template\" style=\";;background:none transparent;border:none;box-shadow:none;padding:0;\">e</abbr></a></li></ul></div><div id=\"Berkeley_Open_Infrastructure_for_Network_Computing_(BOINC)_projects\" style=\"font-size:114%;margin:0 4em\"><a href=\"/wiki/Berkeley_Open_Infrastructure_for_Network_Computing\" title=\"Berkeley Open Infrastructure for Network Computing\">Berkeley Open Infrastructure for Network Computing (BOINC)</a> projects</div></th></tr><tr><th scope=\"row\" class=\"navbox-group\" style=\"width:1%\">Active</th><td class=\"navbox-list-with-group navbox-list navbox-odd hlist\" style=\"width:100%;padding:0\"><div style=\"padding:0 0.25em\">\n<ul><li><a href=\"/wiki/Amicable_Numbers_project\" class=\"mw-redirect\" title=\"Amicable Numbers project\">Amicable Numbers</a></li>\n<li><a href=\"/wiki/Asteroids@home\" class=\"mw-redirect\" title=\"Asteroids@home\">Asteroids@home</a></li>\n<li><a href=\"/wiki/Climateprediction.net\" title=\"Climateprediction.net\">climateprediction.net</a></li>\n<li><a href=\"/wiki/Collatz_Conjecture_project\" class=\"mw-redirect\" title=\"Collatz Conjecture project\">Collatz Conjecture</a></li>\n<li><a href=\"/wiki/Cosmology@Home\" title=\"Cosmology@Home\">Cosmology@Home</a></li>\n<li><a href=\"/wiki/DENIS@Home\" title=\"DENIS@Home\">DENIS@home</a></li>\n<li><a href=\"/wiki/Einstein@Home\" title=\"Einstein@Home\">Einstein@Home</a></li>\n<li><a href=\"/wiki/Gerasim@Home\" class=\"mw-redirect\" title=\"Gerasim@Home\">Gerasim@home</a></li>\n<li><a href=\"/wiki/GPUGRID.net\" title=\"GPUGRID.net\">GPUGRID.net</a></li>\n<li><a href=\"/w/index.php?title=IThena&action=edit&redlink=1\" class=\"new\" title=\"IThena (page does not exist)\">iThena</a></li>\n<li><a href=\"/wiki/LHC@home\" title=\"LHC@home\">LHC@home</a></li>\n<li><a href=\"/w/index.php?title=LODA&action=edit&redlink=1\" class=\"new\" title=\"LODA (page does not exist)\">LODA</a></li>\n<li><a href=\"/wiki/MilkyWay@home\" title=\"MilkyWay@home\">MilkyWay@home</a></li>\n<li><a href=\"/w/index.php?title=Minecraft@home&action=edit&redlink=1\" class=\"new\" title=\"Minecraft@home (page does not exist)\">Minecraft@home</a></li>\n<li><a href=\"/wiki/MindModeling@Home\" title=\"MindModeling@Home\">MindModeling@Home</a></li>\n<li><a href=\"/wiki/Moo!_Wrapper\" class=\"mw-redirect\" title=\"Moo! Wrapper\">Moo! Wrapper</a></li>\n<li><a href=\"/wiki/NFS@Home\" class=\"mw-redirect\" title=\"NFS@Home\">NFS@Home</a></li>\n<li><a href=\"/wiki/NumberFields@home\" class=\"mw-redirect\" title=\"NumberFields@home\">NumberFields@home</a></li>\n<li><a href=\"/wiki/ODLK\" class=\"mw-redirect\" title=\"ODLK\">ODLK</a></li>\n<li><a href=\"/wiki/ODLK1\" class=\"mw-redirect\" title=\"ODLK1\">ODLK1</a></li>\n<li><a href=\"/wiki/PrimeGrid\" title=\"PrimeGrid\">PrimeGrid</a></li>\n<li><a href=\"/w/index.php?title=QuChemPedIA@home&action=edit&redlink=1\" class=\"new\" title=\"QuChemPedIA@home (page does not exist)\">QuChemPedIA@home</a></li>\n<li><a href=\"/w/index.php?title=RakeSearch&action=edit&redlink=1\" class=\"new\" title=\"RakeSearch (page does not exist)\">RakeSearch</a></li>\n<li><a href=\"/w/index.php?title=Ramanujan_Machine&action=edit&redlink=1\" class=\"new\" title=\"Ramanujan Machine (page does not exist)\">Ramanujan Machine</a></li>\n<li><a class=\"mw-selflink selflink\">Rosetta@home</a></li>\n<li><a href=\"/wiki/SIDock@home\" class=\"mw-redirect\" title=\"SIDock@home\">SIDock@home</a></li>\n<li><a href=\"/wiki/SRBase\" class=\"mw-redirect\" title=\"SRBase\">SRBase</a></li>\n<li><a href=\"/w/index.php?title=Universe@Home&action=edit&redlink=1\" class=\"new\" title=\"Universe@Home (page does not exist)\">Universe@Home</a></li>\n<li><a href=\"/wiki/World_Community_Grid\" title=\"World Community Grid\">World Community Grid</a> (subprojects <a href=\"/wiki/Clean_Energy_Project\" title=\"Clean Energy Project\">Clean Energy Project</a>, <a href=\"/wiki/Discovering_Dengue_Drugs_%E2%80%93_Together\" title=\"Discovering Dengue Drugs \u2013 Together\">Discovering Dengue Drugs \u2013 Together</a>, <a href=\"/wiki/FightAIDS@Home\" title=\"FightAIDS@Home\">FightAIDS@Home</a>, <a href=\"/wiki/Fiocruz_Genome_Comparison_Project\" title=\"Fiocruz Genome Comparison Project\">Fiocruz Genome Comparison Project</a>, <a href=\"/wiki/Help_Defeat_Cancer\" title=\"Help Defeat Cancer\">Help Defeat Cancer</a>, <a href=\"/wiki/Help_Conquer_Cancer\" title=\"Help Conquer Cancer\">Help Conquer Cancer</a>, <a href=\"/wiki/Help_Cure_Muscular_Dystrophy\" title=\"Help Cure Muscular Dystrophy\">Help Cure Muscular Dystrophy</a>, <a href=\"/wiki/Human_Proteome_Folding_Project\" title=\"Human Proteome Folding Project\">Human Proteome Folding Project</a>, <a href=\"/wiki/Help_Fight_Childhood_Cancer\" class=\"mw-redirect\" title=\"Help Fight Childhood Cancer\">Help Fight Childhood Cancer</a>, <a href=\"/wiki/Smash_Childhood_Cancer\" class=\"mw-redirect\" title=\"Smash Childhood Cancer\">Smash Childhood Cancer</a>)</li>\n<li><a href=\"/w/index.php?title=WUProp@Home&action=edit&redlink=1\" class=\"new\" title=\"WUProp@Home (page does not exist)\">WUProp@Home</a></li>\n<li><a href=\"/wiki/Yoyo@home\" class=\"mw-redirect\" title=\"Yoyo@home\">yoyo@home</a></li></ul>\n</div></td></tr><tr><th scope=\"row\" class=\"navbox-group\" style=\"width:1%\">Beta</th><td class=\"navbox-list-with-group navbox-list navbox-even hlist\" style=\"width:100%;padding:0\"><div style=\"padding:0 0.25em\">\n<ul><li><a href=\"/w/index.php?title=RNA_World_(beta)&action=edit&redlink=1\" class=\"new\" title=\"RNA World (beta) (page does not exist)\">RNA World (beta)</a></li>\n<li><a href=\"/wiki/Tn-grid\" class=\"mw-redirect\" title=\"Tn-grid\">TN-Grid</a></li>\n<li><a href=\"/w/index.php?title=WEP-M%2B2_Project&action=edit&redlink=1\" class=\"new\" title=\"WEP-M+2 Project (page does not exist)\">WEP-M+2 Project</a></li></ul>\n</div></td></tr><tr><th scope=\"row\" class=\"navbox-group\" style=\"width:1%\">Alpha</th><td class=\"navbox-list-with-group navbox-list navbox-odd hlist\" style=\"width:100%;padding:0\"><div style=\"padding:0 0.25em\">\n<ul><li><a href=\"/w/index.php?title=NanoHUB@home&action=edit&redlink=1\" class=\"new\" title=\"NanoHUB@home (page does not exist)\">nanoHUB@home</a></li>\n<li><a href=\"/w/index.php?title=RADIOACTIVE@HOME&action=edit&redlink=1\" class=\"new\" title=\"RADIOACTIVE@HOME (page does not exist)\">RADIOACTIVE@HOME</a></li>\n<li><a href=\"/w/index.php?title=YAFU&action=edit&redlink=1\" class=\"new\" title=\"YAFU (page does not exist)\">YAFU</a></li></ul>\n</div></td></tr><tr><th scope=\"row\" class=\"navbox-group\" style=\"width:1%\">Technology,<br />tools</th><td class=\"navbox-list-with-group navbox-list navbox-even hlist\" style=\"width:100%;padding:0\"><div style=\"padding:0 0.25em\">\n<ul><li><a href=\"/wiki/BOINC_client%E2%80%93server_technology\" title=\"BOINC client\u2013server technology\">BOINC client\u2013server technology</a></li>\n<li><a href=\"/wiki/BOINC_Credit_System\" title=\"BOINC Credit System\">BOINC Credit System</a></li>\n<li><a href=\"/wiki/Gridcoin\" title=\"Gridcoin\">Gridcoin</a></li>\n<li><a href=\"/wiki/Charity_Engine\" title=\"Charity Engine\">Charity Engine</a></li>\n<li><a href=\"/wiki/GridRepublic\" title=\"GridRepublic\">GridRepublic</a></li>\n<li><a href=\"/wiki/Science_United\" class=\"mw-redirect\" title=\"Science United\">Science United</a></li></ul>\n</div></td></tr><tr><th scope=\"row\" class=\"navbox-group\" style=\"width:1%\">Terminated<br />or inactive</th><td class=\"navbox-list-with-group navbox-list navbox-odd hlist\" style=\"width:100%;padding:0\"><div style=\"padding:0 0.25em\">\n<ul><li><a href=\"/wiki/ABC@Home\" title=\"ABC@Home\">ABC@Home</a></li>\n<li><a href=\"/wiki/AQUA@home\" title=\"AQUA@home\">AQUA@home</a></li>\n<li><a href=\"/wiki/Artificial_Intelligence_System\" title=\"Artificial Intelligence System\">Artificial Intelligence System</a></li>\n<li><a href=\"/wiki/Climateprediction.net#BBC_Climate_Change_Experiment\" title=\"Climateprediction.net\">BBC Climate Change Experiment</a></li>\n<li><a href=\"/wiki/Big_and_Ugly_Rendering_Project\" title=\"Big and Ugly Rendering Project\">Big and Ugly Rendering Project</a></li>\n<li><a 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title=\"EOn\">eOn</a></li>\n<li><a href=\"/wiki/Evolution@Home\" title=\"Evolution@Home\">Evolution@Home</a> (yoyo@home subproject)</li>\n<li><a href=\"/wiki/FreeHAL\" title=\"FreeHAL\">FreeHAL</a></li>\n<li><a href=\"/wiki/HashClash\" title=\"HashClash\">HashClash</a></li>\n<li><a href=\"/wiki/Ibercivis\" title=\"Ibercivis\">Ibercivis</a></li>\n<li><a href=\"/w/index.php?title=Kryptos@Home&action=edit&redlink=1\" class=\"new\" title=\"Kryptos@Home (page does not exist)\">Kryptos@Home</a></li>\n<li><a href=\"/wiki/The_Lattice_Project\" title=\"The Lattice Project\">The Lattice Project</a></li>\n<li><a href=\"/wiki/Leiden_Classical\" title=\"Leiden Classical\">Leiden Classical</a></li>\n<li><a href=\"/wiki/UFluids@Home\" title=\"UFluids@Home\">uFluids@Home</a></li>\n<li><a href=\"/wiki/Malaria_Control_Project\" title=\"Malaria Control Project\">Malaria Control Project</a></li>\n<li><a href=\"/w/index.php?title=MLC@Home&action=edit&redlink=1\" class=\"new\" title=\"MLC@Home (page does 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Attribution Project</a></li>\n<li><a href=\"/wiki/SETI@home\" title=\"SETI@home\">SETI@home</a> (subproject <a href=\"/wiki/Astropulse\" title=\"Astropulse\">Astropulse</a>)</li>\n<li><a href=\"/wiki/SETI@home_beta\" title=\"SETI@home beta\">SETI@home beta</a></li>\n<li><a href=\"/wiki/Similarity_Matrix_of_Proteins\" title=\"Similarity Matrix of Proteins\">SIMAP</a></li>\n<li><a href=\"/wiki/SLinCA@Home\" title=\"SLinCA@Home\">SLinCA@Home</a></li>\n<li><a href=\"/wiki/Spinhenge@Home\" title=\"Spinhenge@Home\">Spinhenge@home</a></li>\n<li><a href=\"/wiki/SZTAKI_Desktop_Grid\" title=\"SZTAKI Desktop Grid\">SZTAKI Desktop Grid</a></li>\n<li><a href=\"/wiki/TANPAKU\" class=\"mw-redirect\" title=\"TANPAKU\">TANPAKU</a></li>\n<li><a href=\"/wiki/TheSkyNet\" title=\"TheSkyNet\">theSkyNet</a></li>\n<li><a href=\"/w/index.php?title=VGTU@Home&action=edit&redlink=1\" class=\"new\" title=\"VGTU@Home (page does not exist)\">VGTU@Home</a></li>\n<li><a href=\"/w/index.php?title=XtremLab&action=edit&redlink=1\" class=\"new\" title=\"XtremLab (page does not exist)\">XtremLab</a></li></ul>\n</div></td></tr></tbody></table></div>\n<p class=\"mw-empty-elt\">\n</p>\n<!-- \nNewPP limit report\nParsed by mw\u2010web.eqiad.main\u201078dcf44494\u2010j98nx\nCached time: 20240509023700\nCache expiry: 2592000\nReduced expiry: false\nComplications: [vary\u2010revision\u2010sha1, show\u2010toc]\nCPU time usage: 0.920 seconds\nReal time usage: 1.068 seconds\nPreprocessor visited node count: 4800/1000000\nPost\u2010expand include size: 247333/2097152 bytes\nTemplate argument size: 1763/2097152 bytes\nHighest expansion depth: 19/100\nExpensive parser function count: 4/500\nUnstrip recursion depth: 1/20\nUnstrip post\u2010expand size: 342275/5000000 bytes\nLua time usage: 0.553/10.000 seconds\nLua memory usage: 4835105/52428800 bytes\nNumber of Wikibase entities loaded: 0/400\n-->\n<!--\nTransclusion expansion time report (%,ms,calls,template)\n100.00% 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