NBD-TMA: Difference between revisions
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'''PM3''' or '''PM-3''' may be: |
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[[Image:NBD-TMA.png|frame|right|NBD-TMA]] |
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'''[[NBD]]-TMA''' ([2-(4-[[nitro compound|nitro]]-2,1,3-[[azole|benzoxadiazol]]-7-yl)[[amine|amino]]ethyl]trimethylammonium) is a small (139 [[Unified atomic mass unit|u]]), positively charged (+1) fluorescent dye. It was also known as '''EAM-1''' (N,N,N,-Trimethyl-2[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanaminium [[iodide]]) when it was briefly supplied by [[Macrocyclics Company]] as an iodide complex. |
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* [[Pm3 (dentistry)]], dental nomenclature for [[molar]] tooth |
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NBD-TMA has an excitation maximum at 458 [[nanometre|nm]] and an emission maximum at 530 nm. It also has a smaller local excitation maximum around 343 nm. The [[molar]] [[extinction coefficient]] is about 13,000 cm<sup>-1</sup>M<sup>-1</sup> and its overall effective fluorescence is about 1% that of [[fluorescein]]. It is only mildly sensitive to [[halide ion]] collision quenching. |
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* [[PM3 (chemistry)]], [[Computational chemistry#Semiempirical methods]] |
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{{disambig}} |
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NBD-TMA was designed as a probe for monitoring [[kidney|renal]] transport of organic [[ion|cation]]s. As a small, positively charged [[fluorophore]], it has also seen use as a tracer for measuring [[gap junction]] coupling in cases of cation selective [[connexin]] channels. |
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== Further reading == |
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* PMID 10864014 |
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* PMID 15869481 |
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[[Category:Dyes]] |
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Revision as of 04:18, 6 April 2007
PM3 or PM-3 may be:
- Pm3 (dentistry), dental nomenclature for molar tooth
- PM3 (chemistry), Computational chemistry#Semiempirical methods
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