MLVA: Difference between revisions
←Created page with '==Definition== MLVA stands for "Multiple Loci VNTR Analysis". "VNTR" means "Variable Number of Tandem Repeats". MLVA is a method employed for the genetic analys...' |
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==Definition== |
==Definition== |
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MLVA stands for "Multiple Loci VNTR Analysis". "[[VNTR]]" means "Variable Number of Tandem Repeats". MLVA is a method employed for the genetic analysis of in particular microorganisms, such as pathogenic bacteria. It takes advantage of the polymorphism of tandemly repeated DNA sequences. This method is well-known in [[forensics]] since it is the basis of [[DNA fingerprinting]] in humans. When applied to bacteria, it contributes to [[forensic microbiology]] through which the source of a particular strain might eventually be traced back. In a typical MLVA assay, a number of well-selected and characterised (in terms of mutation rate and diversity) loci are amplified by polymerase chain reaction ([[PCR]]) so that the size of each locus can be measured. From this size, the number of repeat units at each locu can be deduced. The resulting information is a code which can be easily compared to reference databases. |
MLVA stands for "Multiple Loci VNTR Analysis". "[[VNTR]]" means "Variable Number of Tandem Repeats". MLVA is a method employed for the genetic analysis of in particular microorganisms, such as pathogenic bacteria. It takes advantage of the polymorphism of tandemly repeated DNA sequences. This method is well-known in [[forensics]] since it is the basis of [[DNA fingerprinting]] in humans. When applied to bacteria, it contributes to [[forensic microbiology]] through which the source of a particular strain might eventually be traced back. In a typical MLVA assay, a number of well-selected and characterised (in terms of mutation rate and diversity) loci are amplified by polymerase chain reaction ([[PCR]]) so that the size of each locus can be measured. From this size, the number of repeat units at each locu can be deduced. The resulting information is a code which can be easily compared to reference databases. |
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==Some MLVA associated web sites== |
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* http://bacterial-genotyping.igmors.u-psud.fr/ |
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* http://minisatellites.u-psud.fr/ |
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* http://mlva.u-psud.fr/ |
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* http://mlva.eu/ |
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* http://www.pasteur-guadeloupe.fr:8081/SITVITDemo/ |
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* http://www.umcutrecht.nl/subsite/MLVA/ |
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* http://miru-vntrplus.org/ |
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* http://www.pasteur.fr/recherche/genopole/PF8/mlva/ |
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Revision as of 18:40, 4 January 2008
Definition
MLVA stands for "Multiple Loci VNTR Analysis". "VNTR" means "Variable Number of Tandem Repeats". MLVA is a method employed for the genetic analysis of in particular microorganisms, such as pathogenic bacteria. It takes advantage of the polymorphism of tandemly repeated DNA sequences. This method is well-known in forensics since it is the basis of DNA fingerprinting in humans. When applied to bacteria, it contributes to forensic microbiology through which the source of a particular strain might eventually be traced back. In a typical MLVA assay, a number of well-selected and characterised (in terms of mutation rate and diversity) loci are amplified by polymerase chain reaction (PCR) so that the size of each locus can be measured. From this size, the number of repeat units at each locu can be deduced. The resulting information is a code which can be easily compared to reference databases.