HLA-B59: Difference between revisions

Content deleted Content added

Inline

Revision as of 13:50, 9 April 2019




major histocompatibility complex (human), class I, B59
Alleles	B*5901
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*5901
Locus	chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.^[1] B59 is a hybrid between B*55 and B*51.^[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products^[3]
B*59	B59	Other	Sample
allele	%	%	size (N)
5901	45	41	123

B*5901 allele frequencies

**HLA B*5901 frequencies**
		freq
ref.	Population	(%)
^[4]	Okinawan (USA Hawaii)	6.3
^[4]	Japan (2)	2.7
^[4]	Tarialan Khoton (Mongolia)	2.4
^[4]	South Korea (3)	2.1
^[4]	Gipuscoa Basque (Spain)	2.0
^[4]	Japan Central	1.8
^[4]	Casablanca (Morocco)	1.8
^[4]	Hyogo (Japan)	1.6
^[4]	N. Korean (Harbin,China)	1.0
^[4]	Manchu (Harbin, China)	0.6
^[4]	Naxi (Yunnan, China)	0.6
^[4]	Girona (Catalonia,Spain)	0.6
^[4]	Algeria (1)	0.5
^[4]	Inner Mongolia (China)	0.5
^[4]	Khalkha (Mongolia)	0.5
^[4]	Shanghai (China)	0.3
^[4]	Essen (German )	0.3
^[4]	Southern Han (China)	0.2
^[4]	Shij. Tian. (Beijing, China)	0.1
^[4]	Hakka (Taiwan)	0.1

**Regions of higher B*5901 frequency**
Japan
Korea
Mongolia
Heilongjiang prov., China (Harbin city)

References

^ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMC 2848993. PMID 15787720.
^ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.
^ derived from IMGT/HLA
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. {{cite journal}}: External link in |title= (help)

[pmid15787720-1] Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMC 2848993. PMID 15787720.

[pmid8362411-2] Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens. 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411.

[3] rived from IMGT/HLA

[pmid12753660-4] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l ^m ⁿ ^o ^p ^q ^r ^s ^t Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. {{cite journal}}: External link in |title= (help)

[1]

[2]

[3]

[4]

@@ Line 25: / Line 25: @@
 |}
-'''HLA-B59''' (B59) is an [[Human leukocyte antigen|HLA]]-[[HLA-B|B]] [[serotype]]. The serotype identifies the more common HLA-B*## gene products.<ref name="pmid15787720">{{cite journal  |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x }}</ref> B59 is a hybrid between [[HLA-B55|B*55]] and [[HLA-B51|B*51]].<ref name="pmid8362411">{{cite journal |vauthors=Hildebrand WH, Domena JD, Parham P | title = Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8 | journal = Tissue Antigens | volume = 41 | issue = 4 | pages = 190–5 | year = 1993 | pmid = 8362411 | doi =10.1111/j.1399-0039.1993.tb02001.x }}</ref> B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: [[HLA-A#Historical Guide to Understanding Nomenclature|HLA-serotype tutorial]])
+'''HLA-B59''' (B59) is an [[Human leukocyte antigen|HLA]]-[[HLA-B|B]] [[serotype]]. The serotype identifies the more common HLA-B*## gene products.<ref name="pmid15787720">{{cite journal  |vauthors=Marsh SG, Albert ED, Bodmer WF, etal | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue Antigens | volume = 65 | issue = 4 | pages = 301–69 | year = 2005 | pmid = 15787720 | doi = 10.1111/j.1399-0039.2005.00379.x | pmc = 2848993 }}</ref> B59 is a hybrid between [[HLA-B55|B*55]] and [[HLA-B51|B*51]].<ref name="pmid8362411">{{cite journal |vauthors=Hildebrand WH, Domena JD, Parham P | title = Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8 | journal = Tissue Antigens | volume = 41 | issue = 4 | pages = 190–5 | year = 1993 | pmid = 8362411 | doi =10.1111/j.1399-0039.1993.tb02001.x }}</ref> B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: [[HLA-A#Historical Guide to Understanding Nomenclature|HLA-serotype tutorial]])
 ==Serotype==