Ammonia kinase

In enzymology, an ammonia kinase (EC 2.7.3.8) is an enzyme that catalyzes the chemical reaction

ATP + NH₃ $\rightleftharpoons$ ADP + phosphoramide

Thus, the two substrates of this enzyme are ATP and NH₃, whereas its two products are ADP and phosphoramide.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:ammonia phosphotransferase. Other names in common use include phosphoramidate-adenosine diphosphate phosphotransferase, and phosphoramidate-ADP-phosphotransferase.

References

• Dowler MJ, Nakada HI (1968). "Yeast phosphoramidate-adenosine diphosphate phosphotransferase". J. Biol. Chem. 243: 1434–40. PMID 5647264. 

External links

The CAS registry number for this enzyme class is Template:CAS registry.

• IUBMB entry for 2.7.3.8
• KEGG entry for 2.7.3.8
• BRENDA entry for 2.7.3.8
• NiceZyme view of 2.7.3.8
• EC2PDB: PDB structures for 2.7.3.8
• PRIAM entry for 2.7.3.8
• PUMA2 entry for 2.7.3.8
• IntEnz: Integrated Enzyme entry for 2.7.3.8
• MetaCyc entry for 2.7.3.8
• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047666: ammonia kinase
• AMIGO entry for GO code 0047666: ammonia kinase