List of omics topics in biology
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Inspired by the terms genome and genomics, other words to describe complete datasets of biological data, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome).
List of topics
| -ome | Field of study (-omics) |
Collection of | Parent subject | Notes | |
|---|---|---|---|---|---|
| Bibliome | Bibliomics | Scientific bibliographic data | |||
| Connectome | Connectomics | Structural and functional brain connectivity at different spatiotemporal scales | Neuroscience | ||
| Cytome | Cytomics | Cellular systems of an organism | Cytology | ||
| Exposome (2005) | Exposomics | An individual's environmental exposures, including in the prenatal environment | Molecular genetics | A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture").[1] | |
| Exposome (2009) | Composite occupational exposures and occupational health problems | Occupational safety and health | The proposers of this term were aware of the previous term as used above but proposed to apply the term to a new field.[2][3] | ||
| Exome | Exomics | Exons in a genome | Molecular Genetics | ||
| Genome | Genomics (Classical genetics) |
Genes (DNA sequences/Chromosomes) |
Genetics | "Genome" refers to the set of all genes in an organism. However, "genome" was coined decades before it was discovered that most DNA is "non-coding" and not part of a gene; thus, "genome" originally referred to the entire collection of DNA within an organism. Today, both definitions are used, depending on the context.[4] | |
| Glycome | Glycomics | Glycans | Glycobiology | ||
| Interferome | Interferomics | Interferons | Immunology | Also a database of the same name.[3] | |
| Interactome | Interactomics | All interactions | The term "interactomics" is generally not used. Instead, interactomes are considered the study of systems biology.[5][6] | ||
| Ionome | Ionomics | Inorganic biomolecules | Molecular Biology | ||
| Kinome | Kinomics | Kinases | Molecular Biology | Proteins that add a phosphate group | |
| Lipidome | Lipidomics | Lipids | Biochemistry | ||
| Mechanome | Mechanomics | The mechanical systems within an organism | |||
| Metabolome | Metabolomics | Metabolites | All products of a biological reaction (including intermediates) | ||
| Metagenome | Metagenomics | Genetic material found in an environmental sample | Molecular Biology | The genetic material is assumed to contain DNA from multiple organisms and therefore multiple genomes, hence the inclusion of the prefix meta-. | |
| Metallome | Metallomics | Metals and metalloids | |||
| ORFeome | ORFeomics | Open reading frames (ORFs) | Molecular Genetics | ||
| Organome | Organomics | Organ interactions | Cell Signaling and Tissue Engineering | The study of crosstalk between organs using physiologically relevant in-vitro models | |
| Pharmacogenome | Pharmacogenomics | SNPs and their effect on pharmacokinetics and pharmacodynamics | Pharmacogenetics Genomics |
||
| Phenome | Phenomics | Phenotypes | Genetics | ||
| Physiome | Physiomics | Physiology of an organism | |||
| Proteome | Proteomics | Proteins | Molecular Biology | ||
| Regulome | Regulomics | Transcription factors and other molecules involved in the regulation of gene expression | Molecular Biology | ||
| Secretome | Secretomics | Secreted proteins | Proteomics | Subset of the proteome consisting of proteins actively exported from cells[7]. | |
| Speechome | Speecheomics | Influences on language acquisition | Coined by the Human Speechome Project[8] | ||
| Transcriptome | Transcriptomics | mRNA transcripts | Molecular Biology | ||
| This-has-really-gone-too-far-OME | TooFarOmics | I'm super cereal | Stop! |
Hierarchy of topics
For the sake of clarity, some topics are listed more than once.
References
- ^ Wild CP (2005). "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology". Cancer Epidemiol. Biomarkers Prev. 14 (8): 1847–50. doi:10.1158/1055-9965.EPI-05-0456. PMID 16103423.
- ^ Faisandier, Laurie; De Gaudemaris, Régis; Bicout, Dominique J. (submitted 20 June 2009). "Occupational Health Problem Network : the Exposome". Check date values in:
|date=(help); arXiv:0907.3410 - ^ Faisandier, Laurie; Bonneterre, Vincent; De Gaudemaris, Régis; Bicout, Dominique J. (submitted 20 June 2009). "A network-based approach for surveillance of occupational health exposures". Check date values in:
|date=(help); arXiv:0907.3355 - ^ "genome, n". Oxford English Dictionary. March 2008.
- ^ [1]
- ^ [2]
- ^ Dov Greenbaum, Nicholas M. Luscombe, Ronald Jansen; et al. (2001). "Interrelating Different Types of Genomic Data, from Proteome to Secretome: 'Oming in on Function" (PDF). Genome Research. 11 (9): 1463–1468. doi:10.1101/gr.207401. PMID 11544189.
- ^ BBC article on the Speechome Project
