"(When You Gonna) Give It Up to Me" (known as "Give It Up to Me" in its solo version) is a reggae–dancehall song written by Sean Paul for his third album The Trinity (2005). The single meant to be released after "Temperature" was "Breakout", but was switched to "Give It Up To Me" to promote the film Step Up (2006). It is the fourth U.S. single taken from the album and the fifth UK single. It was a split single with "Never Gonna Be the Same", which was released outside the North America in June 2006 but it was finally released worldwide in October 2006. The version released as a single (the one called "(When You Gonna) Give It Up to Me", in order to differ from the album version) was a collaboration with Keyshia Cole and the song was a single from the Step Up film soundtrack. Despite The Trinity being re-released just before the single release, the version with Keyshia Cole did not make the album, despite a "radio version" being added.
The single climbed as high as number two on the Billboard Hot 100 chart upon its release in the U.S. in the summer of 2006. This became Sean Paul's 6th Top 10 hit and 1st Top 10 hit for Keyshia Cole.
On 30 October 2006, the song was officially released as a single in the UK.