3D model (JSmol)
|Molar mass||167.848 g/mol|
|Appearance||Colorless to pale yellow liquid|
|Melting point||−44 °C (−47 °F; 229 K)|
|Boiling point||146.5 °C (295.7 °F; 419.6 K)|
|1 g/350 mL|
|Vapor pressure||5 mmHg (20°C)|
|Lethal dose or concentration (LD, LC):|
LC50 (median concentration)
|1000 ppm (rat, 4 hr)|
LCLo (lowest published)
|1000 ppm (rat, 4 hr)
643 ppm (mouse, 2 hr)
2714 ppm (cat, 45 min)
|US health exposure limits (NIOSH):|
|TWA 5 ppm (35 mg/m3) [skin]|
|Ca TWA 1 ppm (7 mg/m3) [skin]|
IDLH (Immediate danger)
|Ca [100 ppm]|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
It was once widely used as a solvent and as an intermediate in the industrial production of trichloroethylene, tetrachloroethylene, and 1,2-dichloroethylene. However, 1,1,2,2-tetrachloroethane is no longer used much in the United States due to concerns about its toxicity.
Chronic inhalation exposure in humans results in jaundice and an enlarged liver, headaches, tremors, dizziness, numbness, and drowsiness. The U.S. Environmental Protection Agency has classified it as a Group C possible human carcinogen.
For occupational exposure limits, the Occupational Safety and Health Administration has set a permissible exposure limit for dermal exposures at 5 ppm over an eight-hour time-weighted average. The National Institute for Occupational Safety and Health has a more protective recommended exposure limit for dermal exposures at 1 ppm over an eight-hour time-weighted average.
- Merck Index, 11th Edition, 9125.
- "NIOSH Pocket Guide to Chemical Hazards #0598". National Institute for Occupational Safety and Health (NIOSH).
- "1,1,2,2-Tetrachloroethane". Immediately Dangerous to Life and Health. National Institute for Occupational Safety and Health (NIOSH).
- Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for 1,1,2,2-Tetrachloroethane (Update). U.S. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1996.
- Tetrachloroethane at U.S. EPA
- CDC - NIOSH Pocket Guide to Chemical Hazards