1,2-Naphthoquinone

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1,2-Naphthoquinone
1,2-Naphthoquinone
Names
Other names
o-Naphthoquinone,
β-naphthoquinone
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.007.602
KEGG
Properties
C10H6O2
-67.9·10−6 cm3/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

1,2-Naphthoquinone or ortho-naphthoquinone is a polycyclic aromatic organic compound with formula C
10
H
6
O
2
.

This double ketone (quinone) is a reactive metabolite of naphthalene and is found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.[1]

See also[edit]

References[edit]

  1. ^ Qian, W.; Shichi, H. (2001). "Naphthoquinone-Induced Cataract in Mice: Possible Involvement of Ca2+ Release and Calpain Activation". Journal of Ocular Pharmacology and Therapeutics. 17 (4): 383–392. doi:10.1089/108076801753162799. PMID 11572469. 

External links[edit]