1-alkenyl-2-acylglycerol choline phosphotransferase

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1-alkenyl-2-acylglycerol choline phosphotransferase
Identifiers
EC number 2.7.8.22
CAS number 113066-36-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 1-alkenyl-2-acylglycerol choline phosphotransferase (EC 2.7.8.22) is an enzyme that catalyzes the chemical reaction

CDP-choline + 1-alkenyl-2-acylglycerol CMP + plasmenylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1-alkenyl-2-acylglycerol, whereas its two products are CMP and plasmenylcholine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase. This enzyme is also called CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase. This enzyme participates in ether lipid metabolism.

References[edit]

  • Wientzek M, Man RY, Choy PC (1987). "Choline glycerophospholipid biosynthesis in the guinea pig heart". Biochem. Cell Biol. 65 (10): 860–8. doi:10.1139/o87-112. PMID 3447597.