|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||330.468 g·mol−1|
|3D model (JSmol)|
|(what is this?)|
11-Hydroxy-Δ9-tetrahydrocannabinol (11-OH-THC), usually referred to as 11-hydroxy-THC, is the main active metabolite of tetrahydrocannabinol (THC), which is formed in the body after decarboxylated cannabis is consumed.
Fresh cannabis contains tetrahydrocannabinolic acid (THCA), which is converted into THC after heating and then metabolized by the body into 11-hydroxy-THC and then into 11-nor-9-carboxy-THC; both compounds can be glucuronidated and mainly excreted into urine. Both compounds, along with THC, are assayed in blood tests.
11-hydroxy-THC has a similar psychoactive effect as THC but with a much faster onset of effect. According to animal studies, 11-hydroxy-THC may also have a stronger intensity of "high" experience.
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