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1619 (MDCXIX) was a common year starting on Tuesday of the Gregorian calendar and a common year starting on Friday of the Julian calendar, the 1619th year of the Common Era (CE) and Anno Domini (AD) designations, the 619th year of the 2nd millennium, the 19th year of the 17th century, and the 10th and last year of the 1610s decade. As of the start of 1619, the Gregorian calendar was 10 days ahead of the Julian calendar, which remained in localized use until 1923.
- January – James I of England's Banqueting House, Whitehall in London is destroyed by fire. Inigo Jones is commissioned to design a replacement.
- March – Battle of Sarhu: Manchu leader Nurhaci is victorious over the Ming forces.
- March 20 – Matthias, Holy Roman Emperor dies, leaving the Holy Roman Empire without an official leader, to deal with the Bohemian Revolt.
- May 8 – The Synod of Dort has its final meeting.
- May 13 – Dutch statesman Johan van Oldenbarnevelt is executed in The Hague, after having been convicted of treason.
- May 30 – Jan Pieterszoon Coen, Governor General of the Dutch East Indies, conquers Jayakarta, and renames it Batavia.
- June 10 – Thirty Years' War – Battle of Sablat: Protestant forces are defeated.
- June 21 – Dulwich College founded by Edward Alleyn, in Dulwich, London.
- July 30 – In Jamestown, Virginia, the first representative assembly in the Americas, the House of Burgesses, convenes for the first time.
- August – The first African slaves are brought to North America, on a Dutch trading ship, in the British colony of Jamestown, Virginia.
- August 5 – Thirty Years' War – Battle of Věstonice: Bohemian forces defeat the Austrians.
- August 10 – The Treaty of Angoulême ends the civil war in France.
- August 26 – Frederick V, Elector Palatine is elected the King of Bohemia.
- August 28 – Ferdinand II is elected emperor of the Holy Roman Empire.
- October 8 – Thirty Years' War – The Treaty of Munich is signed by Ferdinand II and Maximilian I, Elector of Bavaria.
- November 16 – William Parker School, Hastings is founded by the will of Reverend William Parker.
- November 23 – Thirty Years' War – Battle of Humenné: Polish troops assist the Holy Roman Emperor by defeating a Transylvanian force, forcing Gabor Bethlen to raise his siege of Vienna.
- December 4 – Thirty-eight colonists from Berkeley Parish, England disembark in Virginia, and give thanks to God (considered by some to be the first Thanksgiving in the Americas).
- January 10 – Philip Sidney, 3rd Earl of Leicester, English politician (d. 1698)
- January 14
- January 17 – Johanna Elisabeth of Nassau-Hadamar, by marriage Princess of Anhalt-Harzgerode (d. 1647)
- January 21
- January 24 – Yamazaki Ansai, Japanese philosopher (d. 1682)
- January 30 – Michelangelo Ricci, Roman Catholic cardinal, mathematician (d. 1682)
- February 1 – Robert Phelips, English politician (d. 1707)
- February 2 – Walter Charleton, English natural philosopher (d. 1707)
- February 9 – Queen Inseon, Korean royal consort (d. 1674)
- February 15 – Tsugaru Nobuyoshi, Japanese daimyo (d. 1655)
- February 24
- February 26 – Francesco Morosini, Doge of Venice from 1688 to 1694 (d. 1694)
- February 28 – Giuseppe Felice Tosi, Italian composer (d. 1693)
- March 2 – Marcantonio Giustinian, 107th Doge of Venice (d. 1688)
- March 5 – Joseph Ames, English naval commander (d. 1695)
- March 6 – Cyrano de Bergerac, French soldier and poet (d. 1655)
- March 13 – Tobias Lohner, Austrian Jesuit theologian (d. 1697)
- March 15 – Jean Le Vacher, French Lazarist missionary and French consul (d. 1683)
- March 20 – Georg Albrecht, Margrave of Brandenburg-Bayreuth-Kulmbach (d. 1666)
- March 25 – Peter Mews, English Royalist theologian and bishop (d. 1706)
- March 28 – Maurice, Duke of Saxe-Zeitz (1657–1681) (d. 1681)
- July 3 – Hyojong of Joseon, 17th king of the Joseon Dynasty of Korea (1649-1659) (d. 1659)
- July 27 – Sir Henry Felton, 2nd Baronet, English Member of Parliament (d. 1690)
- August 5 – Thomas Hall, English politician (d. 1667)
- August 6 – Barbara Strozzi, Italian singer and composer (d. 1677)
- August 7 – Anna Catherine Constance Vasa, Polish princess, daughter of King Sigismund III Vasa (d. 1651)
- August 15
- August 21 – Sir John Borlase, 1st Baronet, English politician (d. 1672)
- August 28
- August 29 – Jean-Baptiste Colbert, French minister of finance (d. 1683)
- September 20 – Sophie Elisabeth Pentz, daughter of Christian IV of Denmark (d. 1657)
- September 21 – Sir John Wray, 3rd Baronet, English politician (d. 1664)
- October 8 – Philipp von Zesen, German poet (d. 1689)
- October 10
- October 14 – Sir John Bright, 1st Baronet, English politician (d. 1688)
- October 16 – Johann Friedrich König, German Lutheran theologian (d. 1664)
- October 18 – Jean Armand de Maillé-Brézé, French admiral (d. 1646)
- October 27 – Frederick Louis, Count Palatine of Zweibrücken (d. 1681)
- November 5 – Philip de Koninck, Dutch painter (d. 1688)
- November 7 – Gédéon Tallemant des Réaux, French writer known for his Historiettes (d. 1692)
- November 14 – Thomas Howard, 3rd Earl of Berkshire, English politician, earl (d. 1706)
- November 25 – Henry Mildmay, English politician (d. 1692)
- December 10 – Thomas Dyke, English politician (d. 1669)
- December 13 – Andrij Savka, Lemko bandit (d. 1661)
- December 17 – Prince Rupert of the Rhine, Bohemian-born Royalist commander in the English Civil War (d. 1682)
- December 28 – Antoine Furetière, French writer (d. 1688)
- December 31
- Donald Cargill, Scottish Covenanter (d. 1681)
- Gu Mei, politically influential Chinese courtesan, poet and painter (d. 1664)
- Samuel Collins, English doctor and author (d. 1670)
- Francisco Fernández de la Cueva, 8th Duke of Alburquerque, Spanish military officer and viceroy (d. 1676)
- Willem Kalf, Dutch painter (d. 1693)
- Kumazawa Banzan, Japanese philosopher (d. 1691)
- Shalom Shabazi, Jewish Yemeni rabbi and poet (d. c. 1720)
- Wang Fuzhi, Chinese philosopher (d. 1692)
- January 7 – Nicholas Hilliard, English miniature painter (b. c. 1547)
- January 11 – Diane de France, Duchess of Angoulême (b. 1538)
- January 15 – Thomas Clinton, 3rd Earl of Lincoln, English politician (b. 1568)
- January 20 – Éléonore de Bourbon, Dutch princess (b. 1587)
- February 3 – Henry Brooke, 11th Baron Cobham, English conspirator (b. 1564)
- February 9 – Lucilio Vanini, Italian philosopher (b. 1585)
- February 12 – Pierre de Larivey, Italian-born French dramatist (b. 1549)
- February 16 – William Couper, Scottish bishop of Galloway (b. 1568)
- March 2
- March 5 – Demeter Naprágyi, Hungarian Catholic archbishop (b. 1564)
- March 13 – Richard Burbage, English actor (b. c. 1567)
- March 15
- March 18 – Chō Tsuratatsu, Japanese samurai (b. 1546)
- March 20
- April 5 – Alexander Home, 1st Earl of Home, Scottish nobleman (b. 1566)
- April 10 – Thomas Jones, Anglican Archbishop of Dublin (b. c. 1550)
- April 16 – Denis Calvaert, Flemish painter (b. 1540)
- April 18 – Taj Bibi Bilqis Makani, Mughal empress (b. 1573)
- April/May – William Larkin, English court portrait painter (b. early 1580s)
- May – John Overall, English bishop (b. 1559)
- May 13 – Johan van Oldenbarnevelt, Dutch statesman (b. 1547)
- May 21 – Hieronymus Fabricius, Italian anatomist (b. 1537)
- May 23 – Stephen Soame, Lord Mayor of London (b. 1540)
- June 18 – Martin Fréminet, French painter (b. 1567)