The 1899 Arkansas Cardinals football team represented the University of Arkansas during the 1899 college football season. The Cardinals played four intercollegiate football games and one game against a high school team from Joplin, Missouri. They compiled a 3–1–1 record and outscored their opponents by a combined total of 37 to 21. The team's one loss came against Oklahoma by an 11–5 score.
The team's roster in 1899 included the following players: Oscar Briggs; Wm. A. Freeman; H. H. Ham; Charles D. Harrison; DeMatt Henderson; Wilburn D. Hobbs; Frank D. James; J. K. McCall; Percy B. Meyer; Chester C. Sloan; Carl C. Smith; James Vanderventer; and Ashton Vincenheller.