Jack Coombs pitched erratically, allowing eight hits and walking nine, but still picked up the win. The Cubs left 14 men on base, a Series record at that time. The A's combed Mordecai Brown for 13 hits, including four doubles in a six-run seventh that put the game away.
All nine players in the lineup for Philadelphia got a hit in Game 2, the first time in World Series history.
Jimmy Archer became the first player in World Series history to appear in a World Series for both the National and American leagues when he took the field in Game 3 for Chicago. Archer played for the Tigers in the 1907 World Series.
Philadelphia entered the series with ten days off compared to only one day off for Chicago – the largest disparity of rest days in World series history.
During the 1910 World Series, a corked baseball was secretly introduced into professional baseball for the first time.