Although they played most of the game in a heavy rainstorm, Alabama opened the 1933 season with a 34–0 victory over Oglethorpe at Denny Stadium. The Crimson Tide took a 14–0 first quarter lead on a 12-yard Frank Moseley touchdown pass to Dixie Howell and a two-yard James McDanal touchdown run. With the lead, Alabama pulled their starters and played their second string for the second quarter. In the second, they took a 21–0 lead on a 21-yard Howard Chappell touchdown run. In the second half, the Crimson Tide closed the game with a touchdown in each of the final two quarters. McDanal scored first on a short run followed by a 12-yard Chappell run for the 34–0 win. The victory improved Alabama's all-time record against Oglethorpe to 2–0.
In what was the first SEC game ever played by the Crimson Tide, Alabama and the rivalOle MissRebels battled to a 0–0 tie at Legion Field. Although Alabama outgained the Rebels in total offense 179 to 33 yards, seven fumbles kept the Crimson Tide out of the end zone. The tie brought Alabama's all-time record against Ole Miss 16–2–2.
Against their long-time rival, the Mississippi StateMaroons, Alabama won their first all-time SEC game 18–0 at Denny Stadium. In the game, Frank Moseley scored on a pair of touchdown runs with Dixie Howell scoring the other in the third quarter on a seven-yard run in the victory. The victory improved Alabama's all-time record against Mississippi State 16–4–2.
Against rivalTennessee, Alabama defeated the Volunteers, 12–6 at Shields-Watkins Field. After a scoreless first quarter, the Volunteers took a 6–0 lead in the second when Beattie Feathers scored on a touchdown run. Down six at the half, a pair of second half touchdowns gave the Crimson Tide the 12–6 victory. Erskine Walker scored in the third on a 34-yard run and Dixie Howell scored the game-winning touchdown in the fourth on a four-yard run. The loss was the first at home for Tennessee in the Robert Neyland era. The victory improved Alabama's all-time record against Tennessee 10–5–1.
Before 60,000 fans at the Polo Grounds in New York City, Alabama was defeated the FordhamRams, 2–0. The only points scored in the game came in the first quarter when Amerino Sarno blocked a Dixie Howellpunt that Howell recovered in the endzone for a Fordham safety. The loss was Alabama's first intersectional loss since their 15–0 defeat against Wisconsin in 1928, and brought Alabama's all-time record against Fordham 0–1.
A week after their first loss of the season, Alabama defeated the KentuckyWildcats 20–0 at Legion Field. After a scoreless first quarter, the Crimson Tide took a 6–0 in the second after Dixie Howell scored on a 55-yard touchdown run. Alabama then closed the game with a five-yard Howell touchdown run in the third and a short Joe Demyanovich touchdown run in the fourth for the 20–0 win. In the first quarter, Howell punted the football 89-yards, which still stands as the Alabama record for longest punt. The victory improved Alabama's all-time record against Kentucky 12–1.
Against the Fighting Gobblers of VPI (now known as the Virginia TechHokies), Alabama won 27–0 on homecoming at Denny Field. The Crimson Tide took a 6–0 first quarter lead after Riley Smith scored on a five-yard touchdown run. They extended their lead to 18–0 at halftime on touchdown runs of one-yard by Joe Demyanovich and ten-yards by James Angelich in the second quarter. Alabama then closed the game with a 16-yard Dixie Howell touchdown run and a tackle of the Gobblers' Ray Mills for a safety in the third for the 27–0 win. The victory improved Alabama's all-time record against VPI 2–0.
Against the Georgia TechGolden Tornado, Alabama won 12–9 at Grant Field. The Crimson Tide took a 6–0 lead in the first quarter on a Dixie Howell touchdown run. After a Howell fumble resulted in a safety in the second, Tech took a 9–6 lead in the third quarter when W. A. Davis scored on a one-yard touchdown run. Howell then scored the game-winning touchdown in the fourth quarter on a short run. The victory improved Alabama's all-time record against Georgia Tech to 7–10–2.
In the season finale at Vanderbilt,Alabama defeated the Commodores 7–0 to capture the first SEC championship. The only points of the game came on a short Dixie Howell touchdown run in the second quarter. The victory improved Alabama's all-time record against Vanderbilt to 6–8.