The first tornado touched down near Bernice, Louisiana, and moved northeast to the Mount Union area, injuring 16 people. The second tornado featured the longest continuous track of the event, traveling 58.3 miles (93.8 km) across northeastern Louisiana and southeastern Arkansas. Both tornadoes caused damage equivalent to F2 intensity. The third tornado became the deadliest event during the outbreak. It touched down over the Mississippi River and moved northeast across the city of Vicksburg, dissipating south of Villanova, Mississippi. The tornado was preceded by heavy rains as it moved through the city. Twelve blocks of the city's business district were affected by the tornado, and fires also burned cotton. The tornado broke the city's gas line, and it remained out of service after repairs. Residents were forced to go without cooked food even as temperatures dropped to 31 °F overnight on December 6. In total, 270 people received injuries. The tornado is officially estimated to have been a F5 tornado on the Fujita scale; however, the rating is questionable, since the tornado demolished frail structures. The final tornado of the day produced F2 damage and caused 11 injuries near the Mississippi River in Coahoma County, Mississippi. In addition, severe thunderstorm winds injured seven people near Clarksdale, Mississippi.
Heavy damages to homes were reported near Spencer and Rocky Branch. 11 injuries were confirmed. 21 or more homes destroyed in Louisiana and nine west and northwest of Montrose, Arkansas. Possibly F3 in intensity as one source indicates.
38 deaths - The tornado destroyed electrical services to the city, and it also initiated several fires. Buildings were "shambles" along four city blocks, and the downtown business district was adversely affected. Many automobiles were submerged by debris. 937 buildings were demolished or received damage, while nearly 1,300 people lost their homes. Damages approached $25 million (1953 USD). F5 rating is disputed due to the frail nature of the structures destroyed.