Rocky Colavito's one-out solo home run in the bottom off the first off of National League starter Bob Purkey gave the American League a 1–0 lead, but Purkey only allowed two walks in the second before Art Mahaffey pitched a scoreless third and fourth, allowing only a leadoff walk to Mickey Mantle in the fourth. The Americans only got three more hits versus Sandy Koufax and Stu Miller.
American starter Jim Bunning pitched three perfect innings, but Don Schwall allowed a bases-loaded single to Bill White that tied the game in the sixth. All five hits the Nationals got were charged to Schwall. Camilo Pascual pitched three shutout innings before the game was called due to rain after nine innings with the score 1–1.