The 1968 NCAA University Division Basketball Tournament involved 23 schools playing in single-elimination play to determine the national champion of men's NCAADivision Icollege basketball. It began on March 8, 1968, and ended with the championship game on March 23 in Los Angeles, California. A total of 27 games were played, including a third place game in each region and a national third place game.
The NCAA semi-final match between the Houston Cougars and UCLA Bruins was a re-match of the college basketball Game of the Century held in January at the Astrodome, in the Cougars' home city. The match was historic, the first nationally syndicated college basketball game and the first to play in a domed stadium before more than 52,000 fans. It was UCLA's only loss in two years, a two-pointer, to the then-#2 Houston, but with UCLA's dominating center Alcindor playing with an eye injury that limited his effectiveness after being hospitalized the week before. The loss broke a 47-game winning streak for UCLA. In the March NCAA Tournament Final 4, the Bruins at full strength avenged that loss with a 101–69 drubbing of that same Houston team, now ranked #1, in UCLA's home city at the Memorial Sports Arena. UCLA limited Houston's Elvin Hayes, who was averaging 37.7 points per game but was held to only 10. Bruins coach John Wooden credited his assistant, Jerry Norman, for devising the diamond-and-one defense that contained Hayes.