The proposed sale of the Chicago White Sox presented opportunities for the Oakland Athletics. A group from Seattle was ready to purchase the White Sox and move them to Seattle. As Charlie Finley had business interests in Chicago, he was prepared to move the Athletics to Chicago. Due to his 20-year lease with the city of Oakland (to expire in 1987), Finley was blocked. In the end, White Sox owner Arthur Allyn sold to Bill Veeck, who kept the White Sox in Chicago.
May 1 – Hank Aaron goes 4-for-4, driving in two runs in the Milwaukee Brewers' 17–3 win over the Detroit Tigers. This brings his career RBI total to 2,211, breaking Babe Ruth's published record of 2,209. On February 3, 1976, the Records Committee will revise Ruth's total to 2,204, meaning that in actuality, Aaron set the record on April 18.
At 5:00 AM, the New York Mets' Cleon Jones is arrested for indecent exposure in St. Petersburg, Florida after police find him naked in a van with a white, teenage girl who is holding a stash of narcotics. The charges are later dropped, however, chairman of the New York Mets M. Donald Grant fines Jones $2,000, four times as much as a Met has ever been assessed before, and forces Jones to publicly apologize during a press conference held in New York, with his wife, Angela, by his side.
May 5 – The Oakland Athletics release pinch runner Herb Washington. Washington, who played in 104 major league games without batting, pitching, or fielding, compiled 31 stolen bases and scored 33 runs. His 1975 trading card (no. 407) is the only Topps card ever issued showing the player's position as 'pinch runner'.
July 17 – For the second consecutive Chicago White Sox game, Wilbur Wood is the starter, and he tosses his second straight shutout, beating the Detroit Tigers 5–0. The two starts were separated by the All-Star game.
July 21 – Félix Millán of the New York Mets has four straight singles but is wiped out each time when Joe Torre grounds into four straight double plays, tying a major league record. New York loses 6–2 to the Houston Astros. Torre is the first National Leaguer to do so.
July 24 – Tom Seaver fans Dan Driessen of the Reds in the second inning for his 2,000th career strikeout. The Reds win, 2-1.
August 9 – Davey Lopes steals his 32nd consecutive base for the Dodgers without being caught, in a 2–0 win over the Mets. This breaks the major league record set by Max Carey in 1922. Lou Brock gets his 2500th hit versus the San Diego Padres, a single in the 6th off of Dave Freisleben at Busch Stadium.
August 21 – Pitching brothers Rick Reuschel and Paul Reuschel combine to hurl the Cubs to a 7–0 victory over the Dodgers — the first time brothers have collaborated on a shutout. Paul takes over when Rick is forced to leave in the 7th inning because of a blister on his finger.
September 1 – Mets ace Tom Seaver shuts out the Pittsburgh Pirates 3-0, and reaches 200 strikeouts for a major league record eighth straight season.
September 2 – The San Francisco Giants' Johnny LeMaster sets a major league record by hitting an inside-the-park home run in his first at bat, during a 7-3 win over the Dodgers. Brian Downing, two years earlier, was the first major league player to hit his first homer inside-the-park, but not in his first at bat.
September 16 – Rennie Stennett ties Wilbert Robinson's major league record, set June 10, 1892, by going 7-for-7 in a nine-inning game. He collects two hits each in the first and fifth innings, and scores five of his club's runs in a 22-0 massacre of the Cubs, a major league record for the biggest score in a shutout game in the 20th century. John Candelaria pockets the easy win, while Rick Reuschel is the loser.
October 21 – Delayed a day by rain, Game Six of the World Series will be among the most memorable. Bernie Carbo of the Red Sox hits a three-run home run in the bottom of the eighth to tie the game. Boston loads the bases with no outs in the ninth but cannot score until Carlton Fisk leads off the twelfth with his memorable walk-off home run, which deflects off the left field foul pole.
November 12 – Tom Seaver of the New York Mets wins his third Cy Young Award, after led the National League pitchers with 22 victories and 243 strikeouts while posting a 2.38 ERA. Seaver had previously won the award in 1969 and 1973.
November 26 – Boston Red Sox center fielder Fred Lynn becomes the first rookie ever to be named American League MVP. Lynn, who hit .331 with 21 home runs and 105 RBI, also posted league-leading figures in runs (103), doubles (47), and slugging (.566), helping Boston to the American League East title. He also won Rookie of the Year honors.
December 10 – A deal to move the Chicago White Sox to Seattle, and the Oakland Athletics to Chicago's South Side, is nixed when Bill Veeck repurchases the White Sox and keeps them in Chicago. Seattle would eventually be awarded with an expansion franchise, called the Mariners.
January 5 – Don Wilson, 29, All-Star pitcher who won 104 games for the Houston Astros, including two no-hitters
January 9 – Curt Fullerton, 76, pitcher for the Boston Red Sox between 1921 and 1933
February 21 – Steve Filipowicz, 55, outfielder for the MLB New York Giants and Cincinnati Reds between 1944 and 1948, previously a running back with the NFL New York Giants in 1943
March 10 – Clint Evans, 85, coach at the University of California from 1930 to 1954 who led team to the first College World Series title in 1947
March 15 – Johnny Gooch, 77, catcher for the 1925 World Series champion Pittsburgh Pirates, who also played for the Brooklyn Dodgers, Cincinnati Reds and Boston Red Sox, and later became a successful minor league manager
March 21 – Joe Medwick, 63, Hall of Fame left fielder and 10-time All-Star who was the last NL player to win the triple crown, also winning the MVP in 1937; lifetime .324 hitter had six 100-RBI seasons for the Cardinals
March 25 – Tommy Holmes, 71, sportswriter who covered the Brooklyn Dodgers from 1924 until the team's move to Los Angeles in 1958
March 26 - Harley Young, 91, pitcher for the Pittsburgh Pirates and Boston Doves in 1908
March 27 – Oscar Fuhr, 81, pitched for the Chicago Cubs and Boston Red Sox between 1921 and 1925
March 28 – Hy Gunning, 86, first baseman for the 1911 Boston Red Sox
April 25 – Bruce Edwards, 51, All-Star catcher for the Brooklyn Dodgers and Chicago Cubs
May 6 – Les Burke, 72, second baseman for the Detroit Tigers from 1923 to 1926
May 10 – Harold Kaese, 66, sportswriter for the Boston Transcript and The Boston Globe from 1933 to 1973
May 22 – Lefty Grove, 75, Hall of Fame pitcher for the Philadelphia Athletics and Boston Red Sox who became the second left-hander to win 300 games, leading AL in ERA nine times and in winning percentage five times, both records; won the pitching triple crown twice, also winning MVP in 1931 after 31-4 campaign; also led AL in strikeouts seven straight years
June 9 – Ownie Carroll, 72, pitcher for the Detroit Tigers, New York Yankees, Cincinnati Reds and Brooklyn Dodgers between 1925 and 1934, who later coached at Seton Hall University for 25 years
June 16 – Clint Courtney, 48, catcher for five AL teams who became the first major leaguer at his position to wear eyeglasses
June 17 – Sid Gordon, 57, All-Star left fielder and third baseman, primarily for the Giants and Braves, who had five 20-HR seasons
July 5 – Joe Kiefer, 75, pitcher for the Chicago White Sox and Boston Red Sox in the 1920s
July 18 – Ted Wingfield, 75, pitcher who played from 1923 to 1927 for the Washington Senators and Boston Red Sox
July 31 – Max Flack, 85, right fielder for the Cubs and Cardinals who batted .300 three times
August 12 – Lew Riggs, 65, All-Star third baseman, mainly for the Cincinnati Reds
August 20 – Daniel Canónico, 59, pitcher who led the Venezuelan team to the 1941 Amateur World Series title, winning five of the team's games including the series-tying and deciding games against Cuba, while placing Venezuela for the very first time among the world baseball elite
September 10 – Lance Richbourg, 77, right fielder for the Boston Braves who batted .308 lifetime
September 28 – Moose Solters, 69, left fielder with four AL teams who batted .300 three times, before his eyesight gradually failed after being hit with a ball during a 1941 warmup
September 29 – Casey Stengel, 85, Hall of Fame manager who won a record ten pennants in twelve seasons leading the Yankees (1949–1960), capturing a record seven titles; also managed Dodgers, Braves and Mets, applying his trademark humor to the Mets in their woeful first season
October 1 – Larry MacPhail, 85, executive who introduced night games, plane travel and pensions to the major leagues while running the Cincinnati Reds, Brooklyn Dodgers and New York Yankees, winning pennants with the latter two teams
October 13 – Swede Risberg, 81, shortstop for the 1917-20 White Sox, and the last survivor among the eight players barred from baseball for their involvement in the Black Sox Scandal
December 1 – Nellie Fox, 47, Hall of Fame second baseman, 12-time All-Star for the Chicago White Sox who formed half of a spectacular middle infield with Luis Aparicio; batted .300 six times, led AL in hits four times, and was 1959 MVP
December 1 – Dave Koslo, 55, pitcher who won over 90 games for the New York Giants
December 9 – Jeff Heath, 60, All-Star left fielder, mainly with the Cleveland Indians, who led the AL in triples twice and batted .300 three times; later a broadcaster
December 12 – Julie Wera, 75, a member of the 1927 World Champions NY Yankees
December 23 – Jim McGlothlin, 32, All-Star pitcher for the California Angels and Cincinnati Reds