Rams rolled to a 17–6 halftime lead behind 2 Pat Haden TD passes, but Ken Stabler led the Oilers back in the second half with 2 TD's of his own. Jeff Rutledge replaced Haden in the 4th and led the Rams to a late game-tying FG. The game appeared headed for OT until Willie Tullis returned the ensuing kickoff for a TD to win it for Houston. Earl Campbell ran for 122 yards.
In a wild contest in Atlanta, the Rams got off to an early 13–0 lead on a punt return TD by Irvin and 2 FG's by Frank Corral. The Falcons' offense kicked into gear and scored three second quarter TDs, two on passes by Steve Bartkowski and a running TD by William Andrews, who had 118 yards. Rutledge replaced an ineffective Haden and kept pace with Bartkowski, throwing 2 TD passes. Falcons led 35–27 late when Irvin returned another punt for a TD, and then Rutledge led the Rams to a last second FG for the win.
Haden was back as the starter, but Rams couldn't hold off a dominating performance by the Cowboys. Tony Dorsett ran for 159 yards and a 44-yard TD and Danny White passed for 277 yards and a 63-yard TD to Tony Hill as the Cowboys rolled to a 26–10 halftime lead and held on and stopped the Rams' 4-game win streak.
Against a surprising 49ers team, the Rams fell behind 14–0 early as Joe Montana tossed two early TD's. Rams nearly came back as Haden passed for a career-high 310 yards and a TD, but the 49ers held on in a battle for NFC West supremacy. It was the Rams' first loss in San Francisco since 1966 and their first-ever loss in Candlestick Park.
Prior to this game, in an apparent "no-confidence" vote for Haden, the Rams signed former Oilers and Raiders QB Dan Pastorini for the remainder of the season. Haden did start this game, but was ineffective as the Rams fell behind 13–7 at the half. Rutledge took over and led the Rams to a 20–13 win, but broke the thumb on his passing hand and would be lost for the season. Tyler scored 2 TD's for the Rams.
Dan Pastorini started his first NFL game in a year and threw a TD pass and led the Rams to an early 13–0 lead. Pastorini also threw four interceptions, and George Rogers led a comeback, rushing for 162 yards and 3 TD's.
Rams hoped to keep their faint playoff hopes alive at home against the surging 49ers. Pastorini started and led the Rams to a 17–10 halftime lead, throwing for a TD. The 49ers scored 17 unanswered points after intermission as Amos Lawrence returned the second half kickoff for a TD, Ray Wersching kicked a FG, and Ronnie Lott returned an interception for a TD. Haden returned and led the Rams to two touchdowns and a 31–30 lead, but the 49ers won on a late FG by Wersching, his fourth of the game.
Rams went back to Haden in this defensive struggle. The defense held the Giants to only 5 pass completions and 148 total yards. The winning FG was set up by a long punt return by Leon Bright. This would be Haden's final NFL start.
The Redskins served notice that they would be a contender in the years to come as they closed out a strong finish after a 0–5 start under new coach Joe Gibbs. Joe Theismann threw for a pair of TD's and John Riggins ran for 2 more.