The NLCS against the Dodgers featured two game-winning home runs by shortstop Ozzie Smith in Game 5 and first baseman Jack Clark in Game 6, both off Dodgers reliever Tom Niedenfuer. In a rare display of power-hitting, Smith hit his in walk-off fashion in the bottom of the ninth inning, prompting the famous call of "Go crazy, folks! Go crazy!" by Jack Buck. This play is considered one of the key highlights in all of Cardinals' history.
The 1985 World Series was christened the "I-70 Series" and the "Show-Me Series" because it featured the in-state rival Kansas City Royals, the first time the two teams met in a non-exhibition setting. It also featured some of the most controversial series of events in Cardinals history. Coleman was unable to play in this Series due to an injury sustained in the NLCS after being rolled up in the mechanical tarpaulin at Busch Stadium. Scribes remarked about the "killer tarp", but it proved metaphorical.
After St. Louis gained a 3–2 series advantage, Game 6 tipped off the controversy with "The Call". With the Cardinals leading 1-0 in the bottom of the ninth inning, umpireDon Denkinger called Royals batter Jorge Orta safe at first base — a call refuted by broadcast television's instant replay. Several batters later, they lost Game 6 by the score of 2–1. After "The Call", St. Louis proceeded to lose Game 7 by a score of 11-0, and thus, the Series, due to an error and passed ball. Despite both of their pitching aces participating in this game, they failed to come through — starter John Tudor, who had won his two prior starts in the Series, punched a mechanical fan when removed from the game. His severely cut pitching hand required stitching at a Kansas City hospital while the game was ongoing. Joaquín Andújar, the other ace pressed into relief, was ejected by home plate umpire Denkinger for arguing balls and strikes.