February 15 – A thirty-two-day lockout begins as Major League Baseball owners refuse to open spring training camp without reaching a new Basic Agreement with the players. The regular season is delayed one week due to the lock-out.
July 17 – The Minnesota Twins turn two triple plays in a single game – the first time that's been accomplished in the major leagues – against the Boston Red Sox, yet still lose the game 1–0 on an unearned run. The following night, the two clubs tie a major league record by turning a combined ten double plays in their game, another Boston victory. Boston ties an American League record by grounding into six double plays in the nine-inning game.
August 27 – At Cleveland Stadium, Boston Red Sox outfielder Ellis Burks hit two home runs in an eight-run 4th inning of a 12–4 victory over the Indians. It is only the second time a Red Sox hitter homers twice in an inning. Bill Regan is the first, on June 16, 1928.
September 19 – At Wrigley Field, Barry Bonds of the Pittsburgh Pirates becomes a first-time member of the 30–30 club. Batting in the fifth inning of the Pirates' 8-7 victory over the Chicago Cubs, Bonds, who had stolen his 49th base earlier in the game, hits his 30th home run off Cub pitcher Bill Long. Bonds will go on to tie his father Bobby for most 30 home run/30 stolen base seasons with five.
October 20: The talk of an Oakland Athletics dynasty is proven premature, as the Cincinnati Reds beat Oakland 2–1 to complete one of the most stunning sweeps in World Series history. Series MVP José Rijo (2–0, 0.59 ERA) retires the last 20 batters he faces to give the Reds their first World Championship since 1976. Not joining the celebration at the end is Eric Davis, who ruptures his kidney diving for a ball during the game and is taken to the hospital. It takes Davis several years to fully recover.
December 6: At Herman Darvick Autograph Auctions in New York City, Shoeless Joe Jackson's signature is sold for $23,100, the most money ever paid for a 19th- or 20th-century signature. Jackson, who did not read or write, copied the signature from one written out by his wife. The signature, which is resold within hours, is cut from a legal document.
January 1 – Carmen Hill, 94, pitcher for three National League teams from 1915 through 1930, who won 22 games in 1927 for the league champions Pittsburgh Pirates
January 2 – Bill Beckmann, 82, pitcher who posted a 21-25 record with a 4.79 ERA in 90 games for the Philadelphia Athletics and St. Louis Cardinals from 1939 through 1942
January 4 – Bobby Balcena, 74, outfielder for the Cincinnati Reds, who during the 1956 season became the first player of Filipino ancestry to appear in a major league game.
January 4 – Bonnie Hollingsworth, 94, pitcher who posted a 4-9 record with a 4.91 ERA in 36 games for the Pittsburgh Pirates, Washington Senators, Brooklyn Robins and Boston Braves from 1922 to 1928
January 6 – Walter Anderson, 92, relief pitcher for the Philadelphia Athletics during the 1917 and 1919 seasons
January 7 – Horace Stoneham, 86, owner of the Giants from 1936 to 1976 who moved the team from New York City to San Francisco for the 1958 season; the team won five NL pennants and the 1954 World Series during his tenure.
January 7 – Shag Thompson, 92, backup outfielder who hit .203 in 48 games for the Philadelphia Athletics from 1914 to 1916
January 9 – Spud Chandler, 82, All-Star pitcher for the New York Yankees who was the AL's MVP in a 20-4 season in 1943; owned career .717 winning percentage.
January 13 – Roy Jarvis, 63, catcher who played for the Brooklyn Dodgers and Pittsburgh Pirates between 1944 and 1947
January 16 – Earl Naylor, 70, backup outfielder for the Philadelphia Phillies (1942–43) and Brooklyn Dodgers (1946)
February 3 – Erv Kantlehner, 97, pitcher who posted a 13-29 record with a 2.84 in 87 games for the Pittsburgh Pirates and Philadelphia Phillies from 1914 to 1916
February 10 – Tony Solaita, 43, first baseman regarded as the only native Samoan ever to play in the majors, who hit .255 with 50 home runs and 203 RBI in 525 games for the Yankees, Royals, Angels and Expos between 1968 and 1979
February 17 – Larry Cox, 42, backup catcher who hit .221 in 382 games with the Phillies, Mariners, Cubs and Rangers (1973–81); later a minor league manager (1983–87) and bullpen coach for the Cubs (1988–89)
February 20 – Cecil Garriott, 73, pinch-hitter for the 1946 Chicago Cubs
February 24 – Tony Conigliaro, 45, All-Star right fielder for the Boston Red Sox who at age 20 became the youngest player ever to win a home run title, but never fully recovered from being hit in the face by a pitch two years later.
February 27 – Vern Freiburger, 66, first baseman for the 1941 Cleveland Indians
March 1 – Creepy Crespi, 72, second baseman for the St. Louis Cardinals during four seasons, including the 1942 World Champion team.
March 6 – Joe Sewell, 91, Hall of Fame shortstop for the Cleveland Indians and New York Yankees who batted .312 lifetime and struck out only 114 times in more than 8,300 plate appearances; led AL in doubles in 1924, and in putouts and assists four times each.
March 9 – Lou Vedder, 92, relief pitcher who appeared in one game for the 1920 Detroit Tigers.
March 11 – Roy Schalk, 81, second baseman for the Chicago White Sox from 1944 to 1945.
March 23 – Margaret Holgerson, 63, All-American Girls Professional Baseball League pitcher who posted a 76-69 record and a 1.94 ERA in seven seasons and hurled a postseason no-hitter.
March 26 – Chet Brewer, 83, All-Star pitcher of the Negro Leagues, later a scout for the Pirates.
March 28 – Johnny Neun, 89, first baseman for the Detroit Tigers and Boston Braves from 1925 to 1931, who in 1927 completed the seventh unassisted triple play in major league history.
March 29 – Phil Masi, 74, a four-time All-Star catcher who played for the Boston Braves, Pittsburgh Pirates and Chicago White Sox between 1939 and 1952.
April 8 – Bill Kelly, 91, first baseman who led the International League in RBI three times (1924–26) and in home runs twice (1924, 1926); played briefly for the Philadelphia Athletics and Philadelphia Phillies in the 1920s, and later managed and umpired in the minors
April 12 – Johnny Reder, 80, Polish sportsman who was a goalkeeper for several American Soccer League teams; played at first base for the 1932 Boston Red Sox, and also was named the New York–Penn League MVP in 1935 while playing with the Williamsport Grays
April 18 – John Antonelli, 74, who spent 70 years in baseball, debuting in 1935 as player/manager in minor leagues at age of 16, appearing at third base in 133 games with the Cardinals and Phillies from 1944 to 1945, and later playing, managing, coaching and instructing in the minors through 1985
April 21 – Johnny Beazley, 71, who went 21–6 with a 2.13 ERA in his 1942 rookie season for the Cardinals and pitched two complete-game wins in the team's World Series over the Yankees.
April 29 – Ray Poat, 72, pitcher who posted a 22-30 record with a 4.55 ERA in 116 games for the Cleveland Indians, New York Giants and Pittsburgh Pirates from 1942 through 1949
August 3 – Bob Brown, 79, pitcher who posted a 16-21 record with a 4.48 ERA in 79 appearances with the Boston Braves/Bees from 1930 to 1936
August 10 – Cookie Lavagetto, 77, All-Star third baseman who, with the Brooklyn Dodgers, spoiled a Yankee no-hitter with two out in the ninth inning of Game Four in the 1947 World Series, hitting a game-winning double; later managed the Senators and Twins.
September 1 – Buster Adams, 75, backup outfielder who hit .266 with 50 home runs and 249 RBI in 576 games for the Cardinals and Phillies from 1939 through 1947
September 2 – Mark Mauldin, 75, backup third baseman who hit .263 with one home run and three RBI in 10 games for the 1934 Chicago White Sox
September 3 – Marshall Bridges, 59, relief pitcher who posted a 23-15 record with a 3.75 ERA and 25 saves in 206 games with the Cardinals, Reds, Yankees and Senators from 1959 to 1965, who during the 1962 World Series became the first American League pitcher to cough up a grand slam in Series history
September 6 – Al Veach, 81, pitcher who posted a 0-2 record for the 1935 Philadelphia Athletics
September 8 – Joe Gleason, 81, pitcher who posted a 2-2 record in 11 games for the Washington Senators in 1920 and 1922
September 9 – Doc Cramer, 85, five-time All-Star center fielder for four AL teams who collected 2,705 hits and was a defensive standout; the only AL player to twice go 6-for-6 in a nine-inning game.
September 12 – Jim Romano, 63, pitcher who appeared in three games for the 1950 Brooklyn Dodgers
September 20 – Dick Gyselman, 82, backup infielder who hit .225 in 82 games for the Boston Braves from 1933 to 1934
October 2 – Heinie Schuble, 83, backup infielder who hit .251 with 11 home runs and 116 RBI in 332 games for the Cardinals and Tigers between 1927 and 1936
October 4 – Vance Dinges, 75, backup first baseman/outfielder who hit .291 with two home runs and 46 RBI in 159 games for the Philadelphia Phillies from 1945 to 1946
October 5 – Dixie Howell, 70, utility catcher for the Pittsburgh Pirates, Cincinnati Reds and Brooklyn Dodgers between 1947 and 1956
October 7 – Walt Ripley, 73, relief pitcher who played briefly for the 1935 Boston Red Sox
October 10 – George Barnicle, 73, pitcher who posted a 3-3 record with a 6.55 ERA in 20 games with the Boston Bees/Braves from 1939 to 1941
October 10 – Wally Moses, 80, All-Star right fielder for the Athletics, White Sox and Red Sox who hit .300 in his first seven seasons, led AL in doubles and triples once each.
October 13 – Lino Donoso, 78, Cuban pitcher who posted a 4-6 record with a 5.21 ERA in 28 games for the Pittsburgh Pirates from 1955 to 1956
October 18 – Nick Etten, 77, All-Star first baseman who hit .277 with 89 home runs and 526 RBI in 937 games with three teams from 1938 to 1946; led American League in home runs (1944) and RBI (1945), and also was a member of the 1943 World Champion New York Yankees
October 21 – Frank Waddey, 85, outfielder who hit .273 in 14 games with the 1931 St. Louis Browns
October 24 – Jim Clark, 63, backup infielder who hit .250 in nine games for the 1948 Washington Senators
November 3 – Jack Russell, 85, All-Star relief pitcher who won 85 games for six teams from 1926 to 1940; twice led American League in saves (1933–34), and later became instrumental in raising money to build a baseball stadium, Jack Russell Memorial Stadium, which became the spring training home of the Phillies in 1955
November 8 – Earl Torgeson, 66, first baseman who hit .389 in 1948 World Series with Boston Braves, led NL in runs in 1950.
November 10 – Aurelio Monteagudo, 46, Cuban pitcher with five teams who also gained renown for pitching in the Venezuelan and Mexican leagues.
November 12 – Junior Walsh, 71, middle-relief pitcher who posted a 4-10 record with a 5.88 ERA and two saves for the Pittsburgh Pirates between the 1946 and 1951 seasons
November 22 – Joe Bowman, 80, pitcher for the Athletics, Giants, Phillies, Pirates, Red Sox, and Reds between 1932 and 1945.
November 23 – Baudilio "Bo" Díaz, 37, All-Star catcher, most notably with the Phillies and Reds, who batted .333 in the 1983 World Series.
November 28 – Tommy Hughes, 71, pitcher who posted a 31-56 record with a .392 ERA in 144 games with the Phillies and Reds between 1941 and 1948