1999 in art
- 28 May – After 22 years of restoration work, Leonardo da Vinci's The Last Supper is placed back on display in Milan, Italy.
- July – After 158 years of an empty plinth, Mark Wallinger's Ecce Homo becomes the first work displayed on the Fourth plinth, Trafalgar Square, London.
- 11 December – After 19 years of work, restoration of the Sistine Chapel frescoes is completed in the Vatican City.
- The Stuckism movement is founded by Billy Childish and Charles Thomson.
- Discovery of Venus of Tan-Tan (300,000–500,000 BP) in Morocco, the earliest known artefact to show evidence of human artistic input.
- Louise Bourgeois – Maman
- Maurizio Cattelan – La Nona Ora (sculpture)
- Mike Chapman – Christ Child (sculpture, London)
- Tracey Emin – My Bed (exhibited at Tate Gallery, London)
- Antony Gormley – Quantum Cloud (sculpture, London)
- Andreas Gursky – color photographs
- Anish Kapoor – Taratantara (Baltic Flour Mill, Gateshead)
- Cornelia Parker – Hanging Fire (Suspected Arson) (installation)
- Beverly Pepper – Persephone Unbound (bronze, Seattle)
- Neo Rauch – Tal
- Archibald Prize – Euan MacLeod, Self portrait/head like a hole
- Schock Prize in Visual Arts – Jacques Herzog and Pierre de Meuron
- Turner Prize – Steve McQueen
-The Venice Biennial-
- The Lion d'or (Golden Lion) for Lifetime Achievement: Louise Bourgeois (USA), Bruce Nauman (USA)
- The Lion d'or for Best Pavilion: Monica Bonvicini, Bruna Esposito, Luisa Lambri, Paola Pivi, Grazia Toderi (Italy)
January to June
- 28 January – Markey Robinson, Irish painter (born 1918)
- 5 February – Nicholas Krushenick, American pop art painter (born 1929)
- 9 February – Richard Allen, American Minimalist, Abstract, Systems, Fundamental and Geometric painter (born 1933)
- 18 February – Andreas Feininger, French-born American photographer (born 1906)
- 10 March – Oswaldo Guayasamín, Ecuadorian painter and sculptor (born 1919)
- 15 March – Harry Callahan, American photographer (born 1912)
- 20 March – Patrick Heron, English painter, writer and designer (born 1920)
- 29 March – Lucien Aigner, Hungarian photographer (born 1901)
- 24 April – Arthur Boyd, Australian painter and sculptor (born 1920)
- 2 May – Tibor Kalman, Hungarian-American graphic designer (born 1949)
- 12 May – Saul Steinberg, Romanian-born American cartoonist and illustrator (born 1914)
- 15 June – John Glashan, Scottish cartoonist, illustrator and playwright (born 1927)
- 19 June – Oton Gliha, Croatian painter (born 1914)
- 30 June – Edouard Boubat, French photographer (born 1923)
July to December
- 14 July – Władysław Hasior, Polish sculptor, painter and set designer (born 1928)
- 15 August – Hugh Casson, British architect, interior designer, artist, writer and broadcaster (born 1910)
- 21 August – Leo Castelli, Italian-American art dealer and gallerist (born 1907)
- 22 August – Yann Goulet, French sculptor, Breton nationalist and war-time collaborationist with Nazi Germany (born 1914)
- 30 August – Raymond Poïvet, French cartoonist (born 1910)
- 13 September – Miriam Davenport, American painter and sculptor (born 1915)
- 4 October – Bernard Buffet, French painter (born 1928)
- 23 October - Albert Tucker, Australian Expressionist painter (born 1914)
- 27 October – Charlotte Perriand, French architect and designer (born 1903)
- 4 November – Richard Clements, Australian painter (born 1951)
- 18 November
- 12 December – Paul Cadmus, American painter (born 1904)
- 28 December – Louis Féraud, French fashion designer and artist (born 1921)
- Alberge, Dayla (2012-03-14). "Have art restorers ruined Leonardo's masterpiece?". The Independent. London. Retrieved 2012-12-21.
- Kennedy, Maev (2000-05-13), "Modern art wins battle of Trafalgar Square: Vacant plinth will be showcase for contemporary sculpture", The Guardian, London
- Arguimbau, Peter Layne (2006-10-05). "Michelangelo's Cleaned off Sistine Chapel". Arguimbau. Archived from the original on 28 September 2007. Retrieved 2007-09-28.
- Morris, Desmond (2013). The Artistic Ape: three million years of art. London: Red Lemon Press. p. 64. ISBN 978-1-78342-002-5.